-
1
-
-
33846230449
-
Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: Are we ready for a prognostically prioritized molecular classification?
-
Mrózek K, Marcucci G, Paschka P, Whitman SP, Bloomfield CD. Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification? Blood. 2007;109:431-448.
-
(2007)
Blood
, vol.109
, pp. 431-448
-
-
Mrózek, K.1
Marcucci, G.2
Paschka, P.3
Whitman, S.P.4
Bloomfield, C.D.5
-
2
-
-
33744455709
-
Biology, clinical relevance, and molecularly targeted therapy in acute leukemia with FLT3 mutation
-
Kiyoi H, Naoe T. Biology, clinical relevance, and molecularly targeted therapy in acute leukemia with FLT3 mutation. Int J Hematol. 2006;83:301-308.
-
(2006)
Int J Hematol
, vol.83
, pp. 301-308
-
-
Kiyoi, H.1
Naoe, T.2
-
3
-
-
19944427850
-
Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype
-
for the GIMEMA Acute Leukemia Working Party
-
Falini B, Mecucci C, Tiacci E, et al, for the GIMEMA Acute Leukemia Working Party. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. N Engl J Med. 2005;352:254-266.
-
(2005)
N Engl J Med
, vol.352
, pp. 254-266
-
-
Falini, B.1
Mecucci, C.2
Tiacci, E.3
-
4
-
-
0031686409
-
Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product
-
Kiyoi H, Towatari M, Yokota S, et al. Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product. Leukemia. 1998;12:1333-1337.
-
(1998)
Leukemia
, vol.12
, pp. 1333-1337
-
-
Kiyoi, H.1
Towatari, M.2
Yokota, S.3
-
5
-
-
23744444913
-
Prognostic significance of FLT3 internal tandem duplication and tyrosine kinase domain mutations for acute myeloid leukemia: A meta-analysis
-
Yanada M, Matsuo K, Suzuki T, Kiyoi H, Naoe T. Prognostic significance of FLT3 internal tandem duplication and tyrosine kinase domain mutations for acute myeloid leukemia: a meta-analysis. Leukemia. 2005;19:1345-1349.
-
(2005)
Leukemia
, vol.19
, pp. 1345-1349
-
-
Yanada, M.1
Matsuo, K.2
Suzuki, T.3
Kiyoi, H.4
Naoe, T.5
-
6
-
-
0035885955
-
The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials
-
Kottaridis PD, Gale RE, Frew ME, et al. The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials. Blood. 2001;98:1752-1759.
-
(2001)
Blood
, vol.98
, pp. 1752-1759
-
-
Kottaridis, P.D.1
Gale, R.E.2
Frew, M.E.3
-
7
-
-
0037097716
-
Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
-
Thiede C, Steudel C, Mohr B, et al. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis. Blood. 2002;99:4326-4335.
-
(2002)
Blood
, vol.99
, pp. 4326-4335
-
-
Thiede, C.1
Steudel, C.2
Mohr, B.3
-
8
-
-
0024966024
-
Major nucleolar proteins shuttle between nucleus and cytoplasm
-
Borer RA, Lehner CF, Eppenberger HM, Nigg EA. Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell. 1989;56:379-390.
-
(1989)
Cell
, vol.56
, pp. 379-390
-
-
Borer, R.A.1
Lehner, C.F.2
Eppenberger, H.M.3
Nigg, E.A.4
-
9
-
-
0024305925
-
Interaction of nucleolar phosphoprotein B23 with nucleic acids
-
Dumbar TS, Gentry GA, Olson MO. Interaction of nucleolar phosphoprotein B23 with nucleic acids. Biochemistry. 1989;28:9495-9501.
-
(1989)
Biochemistry
, vol.28
, pp. 9495-9501
-
-
Dumbar, T.S.1
Gentry, G.A.2
Olson, M.O.3
-
10
-
-
0036052920
-
A mammalian in vitro centriole duplication system: Evidence for involvement of CDK2/cyclin E and nucleophosmin/B23 in centrosome duplication
-
Tarapore P, Okuda M, Fukasawa K. A mammalian in vitro centriole duplication system: evidence for involvement of CDK2/cyclin E and nucleophosmin/B23 in centrosome duplication. Cell Cycle. 2002;1:75-81.
-
(2002)
Cell Cycle
, vol.1
, pp. 75-81
-
-
Tarapore, P.1
Okuda, M.2
Fukasawa, K.3
-
11
-
-
0025880226
-
Nucleolin promotes secondary structure in ribosomal RNA
-
Sipos K, Olson MO. Nucleolin promotes secondary structure in ribosomal RNA. Biochem Biophys Res Commun. 1991;177:673-678.
-
(1991)
Biochem Biophys Res Commun
, vol.177
, pp. 673-678
-
-
Sipos, K.1
Olson, M.O.2
-
12
-
-
24144494881
-
Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia
-
Suzuki T, Kiyoi H, Ozeki K, et al. Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia. Blood. 2005;106:2854-2861.
-
(2005)
Blood
, vol.106
, pp. 2854-2861
-
-
Suzuki, T.1
Kiyoi, H.2
Ozeki, K.3
-
13
-
-
27744502042
-
Prevalence, clinical profile, and prognosis of NPM mutations in AML with normal karyotype
-
for the Acute Leukemia French Association ALFA
-
Boissel N, Renneville A, Biggio V, et al, for the Acute Leukemia French Association (ALFA). Prevalence, clinical profile, and prognosis of NPM mutations in AML with normal karyotype. Blood. 2005;106:3618-3620.
-
(2005)
Blood
, vol.106
, pp. 3618-3620
-
-
Boissel, N.1
Renneville, A.2
Biggio, V.3
-
14
-
-
28444449081
-
Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype
-
Schnittger S, Schoch C, Kern W, et al. Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype. Blood. 2005;106:3733-3739.
-
(2005)
Blood
, vol.106
, pp. 3733-3739
-
-
Schnittger, S.1
Schoch, C.2
Kern, W.3
-
15
-
-
28444473100
-
Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: Interaction with other gene mutations
-
for the AML Study Group AMLSG
-
Döhner K, Schlenk RF, Habdank M, et al, for the AML Study Group (AMLSG). Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations. Blood. 2005;106:3740-3746.
-
(2005)
Blood
, vol.106
, pp. 3740-3746
-
-
Döhner, K.1
Schlenk, R.F.2
Habdank, M.3
-
16
-
-
28444446313
-
Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): Association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance
-
Verhaak RG, Goudswaard CS, van Putten W, et al. Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance. Blood. 2005;106:3747-3754.
-
(2005)
Blood
, vol.106
, pp. 3747-3754
-
-
Verhaak, R.G.1
Goudswaard, C.S.2
van Putten, W.3
-
17
-
-
33646557337
-
-
Thiede C, Koch S, Creutzig E, et al, for the Deutsche Studieninitiative Leukämie (DSIL). Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML). Blood. 2006;107:4011-4020.
-
Thiede C, Koch S, Creutzig E, et al, for the Deutsche Studieninitiative Leukämie (DSIL). Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML). Blood. 2006;107:4011-4020.
-
-
-
-
18
-
-
29144468876
-
A randomized, postremission comparison of four courses of standard-dose consolidation therapy without maintenance therapy versus three courses of standard-dose consolidation with maintenance therapy in adults with acute myeloid leukemia: The Japan Adult Leukemia Study Group AML 97 Study
-
and the Japan Adult Leukemia Study Group
-
Miyawaki S, Sakamaki H, Ohtake S, et al, and the Japan Adult Leukemia Study Group. A randomized, postremission comparison of four courses of standard-dose consolidation therapy without maintenance therapy versus three courses of standard-dose consolidation with maintenance therapy in adults with acute myeloid leukemia: the Japan Adult Leukemia Study Group AML 97 Study. Cancer. 2005;104:2726-2734.
-
(2005)
Cancer
, vol.104
, pp. 2726-2734
-
-
Miyawaki, S.1
Sakamaki, H.2
Ohtake, S.3
-
19
-
-
34347386848
-
A randomized study with or without intensified maintenance chemotherapy in patients with acute promyelocytic leukemia who have become negative for PML-RARα transcript after consolidation therapy: The Japan Adult Leukemia Study Group (JALSG) APL97 study
-
for the Japan Adult Leukemia Study Group
-
Asou N, Kishimoto Y, Kiyoi H, et al, for the Japan Adult Leukemia Study Group. A randomized study with or without intensified maintenance chemotherapy in patients with acute promyelocytic leukemia who have become negative for PML-RARα transcript after consolidation therapy: the Japan Adult Leukemia Study Group (JALSG) APL97 study. Blood. 2007;110:59-66.
-
(2007)
Blood
, vol.110
, pp. 59-66
-
-
Asou, N.1
Kishimoto, Y.2
Kiyoi, H.3
-
20
-
-
0032188805
-
on behalf of the Medical Research Council Adult and Children's Leukaemia Working Parties. The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial
-
Grimwade D, Walker H, Oliver F, et al, on behalf of the Medical Research Council Adult and Children's Leukaemia Working Parties. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. Blood. 1998;92:2322-2333.
-
(1998)
Blood
, vol.92
, pp. 2322-2333
-
-
Grimwade, D.1
Walker, H.2
Oliver, F.3
-
21
-
-
0033134792
-
Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia
-
Kiyoi H, Naoe T, Nakano Y, et al. Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia. Blood. 1999;93:3074-3080.
-
(1999)
Blood
, vol.93
, pp. 3074-3080
-
-
Kiyoi, H.1
Naoe, T.2
Nakano, Y.3
-
22
-
-
27744451026
-
No evidence that FLT3 status should be considered as an indicator for transplantation in acute myeloid leukemia (AML): An analysis of 1135 patients, excluding acute promyelocytic leukemia, from the UK MRC AML10 and 12 trials
-
Gale RE, Hills R, Kottaridis PD, et al. No evidence that FLT3 status should be considered as an indicator for transplantation in acute myeloid leukemia (AML): an analysis of 1135 patients, excluding acute promyelocytic leukemia, from the UK MRC AML10 and 12 trials. Blood. 2005;106:3658-3665.
-
(2005)
Blood
, vol.106
, pp. 3658-3665
-
-
Gale, R.E.1
Hills, R.2
Kottaridis, P.D.3
-
23
-
-
33847417644
-
Improved outcome after stem-cell transplantation in FLT3/ITD-positive AML
-
and the AML SHG 96 Study Group
-
Bornhäuser M, Illmer T, Schaich M, Soucek S, Ehninger G, Thiede C, and the AML SHG 96 Study Group. Improved outcome after stem-cell transplantation in FLT3/ITD-positive AML. Blood. 2007;109:2264-2265.
-
(2007)
Blood
, vol.109
, pp. 2264-2265
-
-
Bornhäuser, M.1
Illmer, T.2
Schaich, M.3
Soucek, S.4
Ehninger, G.5
Thiede, C.6
-
24
-
-
33645501151
-
Nucleophosmin mutations in de novo acute myeloid leukemia: The age-dependent incidences and the stability during disease evolution
-
Chou WC, Tang JL, Lin LI, et al. Nucleophosmin mutations in de novo acute myeloid leukemia: the age-dependent incidences and the stability during disease evolution. Cancer Res. 2006;66:3310-3316.
-
(2006)
Cancer Res
, vol.66
, pp. 3310-3316
-
-
Chou, W.C.1
Tang, J.L.2
Lin, L.I.3
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