p-Nonylphenol induces endoplasmic reticulum stress-mediated apoptosis in neuronally differentiated PC12 cells

Neuroscience Letters

Volumn 431, Issue 3, 2008, Pages 256-261

  Kusunoki, Takashi ^a   Shimoke, Koji ^a   Komatsubara, Satoko ^a   Kishi, Soichiro ^a   Ikeuchi, Toshihiko ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Endocrine disrupting chemical; ER stress; Estrogen; PC12 cell

Indexed keywords

4 NONYLPHENOL; CALCIUM; CASPASE 12; GLUCOSE REGULATED PROTEIN 78; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL SURVIVAL; CHELATING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EGTAZIC ACID; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 3; MOLECULAR CHAPERONES; NERVE GROWTH FACTOR; NEURONS; PC12 CELLS; PHENOLS; RATS;

EID: 38349042185     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.11.058     Document Type: Article

References (27)

1. Allan L.A., Morrice N., Brady S., Magee G., Pathak S., and Clarke P.R. Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK. Nat. Cell. Biol. 5 (2003) 647-654
2. Barbacid M. Neurotrophic factors and their receptors. Curr. Opin. Cell. Biol. 7 (1995) 148-155
3. Bechi N., Ietta F., Romagnoli R., Focardi S., Corsi I., Buffi C., and Paulesu L. Estrogen-like response to p-nonylphenol in human first trimester placenta and BeWo choriocarcinoma cells. Toxicol. Sci. 93 (2006) 75-81
4. Bhatnagar V., Patel J., Variya M., Venkaiah K., Shan M., and Kashyap S. Levels of organochkorine insecticides in human blood from Ahmedabad (rural), India. Bull. Environ. Contam. Toxicol. 48 (1992) 302-307
5. Brunet A., Datta S.R., and Greenberg M.E. Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr. Opin. Neurobiol. 11 (2001) 297-305
6. Crowder R.J., and Freeman R.S. Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons. J. Neurosci. 18 (1998) 2933-2943
7. Hitomi J., Katayama T., Taniguchi M., Honda A., Imaizumi K., and Tohyama M. Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12. Neurosci. Lett. 357 (2004) 127-130
8. Ho S., and Yu M. Selective increase in type II estorogen-binding sites in the dysplastic dorsolateral prostates of noble rats. Cancer Res. 53 (1993) 528-532
9. Hughes P.J., McLellan H., Lowes D.A., Kahn S.Z., Bilmen J.G., Tovey S.C., Godfrey R.E., Michell R.H., Kirk C.J., and Michelangeli F. Estrogenic alkylphenols induce cell death by inhibiting testis endoplasmic reticulum Ca(2+) pumps. Biochem. Biophys. Res. Commun. 277 (2000) 568-574
10. Kaplan D.R., and Miller F.D. Neurotrophin signal transduction in the nervous system. Curr. Opin. Neurobiol. 10 (2000) 381-391
11. Kaufman R.J. Orchestrating the unfolded protein response in health and disease. J. Clin. Invest. 110 (2002) 1389-1398
12. Koji T., and Hishikawa Y. Germ cell apoptosis and its molecular trigger in mouse testes. Arch. Histol. Cytol. 66 (2003) 1-16
13. McClusky L.M., de Jager C., and Bornman M.S. Stage-related increase in the proportion of apoptotic germ cells and altered frequencies of stages in the spermatogenic cycle following gestational, lactational, and direct exposure of male rats to p-nonylphenol. Toxicol. Sci. 95 (2007) 249-256
14. Morishima N., Nakanishi K., Takenouchi H., Shibata T., and Yasuhiko Y. An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J. Biol. Chem. 277 (2002) 34287-34294
15. Nakagawa T., and Yuan J. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J. Cell. Biol. 150 (2000) 887-894
16. Newbold R.R., Hanson R.B., Jefferson W.N., Bullock B.C., Haseman J., and McLachlan J.A. Proliferative lesions and reproductive tract tumors in male descendants of mice exposed developmentally to diethylstilbestrol. Carcinogenesis 21 (2000) 1355-1363
17. Pujol P., Hilsenbeck S., Chamness G., and Elledge R. Rising levels of estrogen receptor in breast cancer over 2 decades. Cancer 74 (1994) 1601-1606
18. Rao R.V., and Bredesen D.E. Misfolded proteins, endoplasmic reticulum stress and neurodegeneration. Curr. Opin. Cell. Biol. 16 (2004) 653-662
19. Sharpe R., and Skakkebaek N. Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract?. Lancet 341 (1993) 1392-1395
20. Shimoke K., Amano H., Kishi S., Uchida H., Kudo M., and Ikeuchi T. Nerve growth factor attenuates endoplasmic reticulum stress-mediated apoptosis via suppression of caspase-12 activity. J. Biochem. 135 (2004) 439-446
21. Shimoke K., Kishi S., Utsumi T., Shimamura Y., Sasaya H., Oikawa T., Uesato S., and Ikeuchi T. NGF-induced phosphatidylinositol 3-kinase signaling pathway prevents thapsigargin-triggered ER stress-mediated apoptosis in PC12 cells. Neurosci. Lett. 389 (2005) 124-128
22. Shimoke K., Utsumi T., Kishi S., Nishimura M., Sasaya H., Kudo M., and Ikeuchi T. Prevention of endoplasmic reticulum stress-induced cell death by brain-derived neurotrophic factor in cultured cerebral cortical neurons. Brain Res. 1028 (2004) 105-111
23. Shimoke K., Yamagishi S., Yamada M., Ikeuchi T., and Hatanaka H. Inhibition of phosphatidylinositol 3-kinase activity elevates c-Jun N-terminal kinase activity in apoptosis of cultured cerebellar granule neurons. Dev. Brain Res. 112 (1999) 245-253
24. Thoenen H. Neurotrophins and neuronal plasticity. Science 270 (1995) 593-598
25. Vaudry D., Stork P.J., Lazarovici P., and Eiden L.E. Signaling pathways for PC12 cell differentiation: making the right connections. Science 296 (2002) 1648-1649
26. Xia Z., Dickens M., Raingeaud J., Davis R.J., and Greenberg M.E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270 (1995) 1326-1331
27. Yamagishi S., Matsumoto T., Numakawa T., Yokomaku D., Adachi N., Hatanaka H., Yamada M., Shimoke K., and Ikeuchi T. ERK1/2 are involved in low potassium-induced apoptotic signaling downstream of ASK1-p38 MAPK pathway in cultured cerebellar granule neurons. Brain Res. 1038 (2005) 223-230