메뉴 건너뛰기




Volumn 294, Issue 1, 2008, Pages

Oxyntomodulin ameliorates glucose intolerance in mice fed a high-fat diet

Author keywords

Animal model; Glucose tolerance; Gut hormone; Hyperinsulinemic euglycemic clamp; Insulin

Indexed keywords

INSULIN; OXYNTOMODULIN;

EID: 38349016311     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00576.2007     Document Type: Article
Times cited : (41)

References (45)
  • 1
    • 9244224088 scopus 로고    scopus 로고
    • Effects of peptide YY[3-36] on short-term food intake in mice are not affected by prevailing plasma ghrelin levels
    • Adams SH, Won WB, Schonhoff SE, Leiter AB, Paterniti JR Jr. Effects of peptide YY[3-36] on short-term food intake in mice are not affected by prevailing plasma ghrelin levels. Endocrinology 145: 4967-4975, 2004.
    • (2004) Endocrinology , vol.145 , pp. 4967-4975
    • Adams, S.H.1    Won, W.B.2    Schonhoff, S.E.3    Leiter, A.B.4    Paterniti Jr., J.R.5
  • 2
    • 26244438849 scopus 로고    scopus 로고
    • Reduced insulin clearance contributes to the increased insulin levels after administration of glucagon-like peptide 1 in mice
    • Ahren B, Thomaseth K, Pacini G. Reduced insulin clearance contributes to the increased insulin levels after administration of glucagon-like peptide 1 in mice. Diabetologia 48: 2140-2146, 2005.
    • (2005) Diabetologia , vol.48 , pp. 2140-2146
    • Ahren, B.1    Thomaseth, K.2    Pacini, G.3
  • 3
    • 4143116741 scopus 로고    scopus 로고
    • Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure
    • Baggio LL, Huang Q, Brown TJ, Drucker DJ. Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure. Gastroenterology 127: 546-558, 2004.
    • (2004) Gastroenterology , vol.127 , pp. 546-558
    • Baggio, L.L.1    Huang, Q.2    Brown, T.J.3    Drucker, D.J.4
  • 4
    • 0023910424 scopus 로고
    • Oxyntomodulin [glicentin-(33- 69)]: Pharmacokinetics, binding to liver cell membranes, effects on isolated perfused pig pancreas, and secretion from isolated perfused lower small intestine of pigs
    • Baldissera FG, Holst JJ, Knuhtsen S, Hilsted L, Nielsen OV. Oxyntomodulin [glicentin-(33- 69)]: pharmacokinetics, binding to liver cell membranes, effects on isolated perfused pig pancreas, and secretion from isolated perfused lower small intestine of pigs. Regul Pept 21: 151-166, 1988.
    • (1988) Regul Pept , vol.21 , pp. 151-166
    • Baldissera, F.G.1    Holst, J.J.2    Knuhtsen, S.3    Hilsted, L.4    Nielsen, O.V.5
  • 5
    • 0033436355 scopus 로고    scopus 로고
    • Insulin and leptin: Dual adiposity signals to the brain for the regulation of food intake and body weight
    • Baskin DG, Figlewicz LD, Seeley RJ, Woods SC, Porte D Jr, Schwartz MW. Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight. Brain Res 848: 114-123, 1999.
    • (1999) Brain Res , vol.848 , pp. 114-123
    • Baskin, D.G.1    Figlewicz, L.D.2    Seeley, R.J.3    Woods, S.C.4    Porte Jr, D.5    Schwartz, M.W.6
  • 6
    • 0020377971 scopus 로고
    • Isolation of glucagon-37 (bioactive enteroglucagon/oxyntomodulin) from porcine jejuno-ileum. Characterization of the peptide
    • Bataille D, Tatemoto K, Gespach C, Jornvall H, Rosselin G, Mutt V. Isolation of glucagon-37 (bioactive enteroglucagon/oxyntomodulin) from porcine jejuno-ileum. Characterization of the peptide. FEBS Lett 146: 79-86, 1982.
    • (1982) FEBS Lett , vol.146 , pp. 79-86
    • Bataille, D.1    Tatemoto, K.2    Gespach, C.3    Jornvall, H.4    Rosselin, G.5    Mutt, V.6
  • 8
    • 0024236086 scopus 로고
    • Oxyntomodulin and glicentin: Braingut peptides in the rat
    • Blache P, Kervran A, Bataille D. Oxyntomodulin and glicentin: braingut peptides in the rat. Endocrinology 123: 2782-2787, 1988.
    • (1988) Endocrinology , vol.123 , pp. 2782-2787
    • Blache, P.1    Kervran, A.2    Bataille, D.3
  • 10
    • 38349058997 scopus 로고    scopus 로고
    • Exenatide (Byetta) as a novel treatment option for type 2 diabetes mellitus
    • Bond A. Exenatide (Byetta) as a novel treatment option for type 2 diabetes mellitus. Proc (Bayl Univ Med Cent) 19: 281-284, 2006.
    • (2006) Proc (Bayl Univ Med Cent) , vol.19 , pp. 281-284
    • Bond, A.1
  • 17
    • 2442555002 scopus 로고    scopus 로고
    • Glucagon promotes cAMP-response element-binding protein phosphorylation via activation of ERK1/2 in MIN6 cell line and isolated islets of Langerhans
    • Dalle S, Longuet C, Costes S, Broca C, Faruque O, Fontes G, Hani EH, Bataille D. Glucagon promotes cAMP-response element-binding protein phosphorylation via activation of ERK1/2 in MIN6 cell line and isolated islets of Langerhans. J Biol Chem 279: 20345-20355, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 20345-20355
    • Dalle, S.1    Longuet, C.2    Costes, S.3    Broca, C.4    Faruque, O.5    Fontes, G.6    Hani, E.H.7    Bataille, D.8
  • 18
    • 0030012124 scopus 로고    scopus 로고
    • Role of prohormone convertases in the tissue-specific processing of proglucagon
    • Dhanvantari S, Seidah NG, Brubaker PL. Role of prohormone convertases in the tissue-specific processing of proglucagon. Mol Endocrinol 10: 342-355, 1996.
    • (1996) Mol Endocrinol , vol.10 , pp. 342-355
    • Dhanvantari, S.1    Seidah, N.G.2    Brubaker, P.L.3
  • 19
    • 0019983555 scopus 로고
    • Oxyntomodulin (glucagon-37 or bioactive enteroglucagon): A potent inhibitor of pentagastrin-stimulated acid secretion in rats
    • Dubrasquet M, Bataille D, Gespach C. Oxyntomodulin (glucagon-37 or bioactive enteroglucagon): a potent inhibitor of pentagastrin-stimulated acid secretion in rats. Biosci Rep 2: 391-395, 1982.
    • (1982) Biosci Rep , vol.2 , pp. 391-395
    • Dubrasquet, M.1    Bataille, D.2    Gespach, C.3
  • 20
    • 0020509994 scopus 로고
    • Molecular forms of human enteroglucagon in tissue and plasma: Plasma responses to nutrient stimuli in health and in disorders of the upper gastrointestinal tract
    • Ghatei MA, Uttenthal LO, Christofides ND, Bryant MG, Bloom SR. Molecular forms of human enteroglucagon in tissue and plasma: plasma responses to nutrient stimuli in health and in disorders of the upper gastrointestinal tract. J Clin Endocrinol Metab 57: 488-495, 1983.
    • (1983) J Clin Endocrinol Metab , vol.57 , pp. 488-495
    • Ghatei, M.A.1    Uttenthal, L.O.2    Christofides, N.D.3    Bryant, M.G.4    Bloom, S.R.5
  • 22
    • 0027220436 scopus 로고
    • Glucagon-like peptide-1-(7-36) amide, oxyntomodulin, and glucagon interact with a common receptor in a somatostatin-secreting cell line
    • Gros L, Thorens B, Bataille D, Kervran A. Glucagon-like peptide-1-(7-36) amide, oxyntomodulin, and glucagon interact with a common receptor in a somatostatin-secreting cell line. Endocrinology 133: 631-638, 1993.
    • (1993) Endocrinology , vol.133 , pp. 631-638
    • Gros, L.1    Thorens, B.2    Bataille, D.3    Kervran, A.4
  • 24
    • 0023104829 scopus 로고
    • Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut
    • Holst JJ, Orskov C, Nielsen OV, Schwartz TW. Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut. FEBS Lett 211: 169-174, 1987.
    • (1987) FEBS Lett , vol.211 , pp. 169-174
    • Holst, J.J.1    Orskov, C.2    Nielsen, O.V.3    Schwartz, T.W.4
  • 25
    • 0033847126 scopus 로고    scopus 로고
    • Glucagon receptors on human islet cells contribute to glucose competence of insulin release
    • Huypens P, Ling Z, Pipeleers D, Schuit F. Glucagon receptors on human islet cells contribute to glucose competence of insulin release. Diabetologia 43: 1012-1019, 2000.
    • (2000) Diabetologia , vol.43 , pp. 1012-1019
    • Huypens, P.1    Ling, Z.2    Pipeleers, D.3    Schuit, F.4
  • 26
    • 0021259313 scopus 로고
    • A pure enteroglucagon, oxyntomodulin (glucagon 37), stimulates insulin release in perfused rat pancreas
    • Jarrousse C, Bataille D, Jeanrenaud B. A pure enteroglucagon, oxyntomodulin (glucagon 37), stimulates insulin release in perfused rat pancreas. Endocrinology 115: 102-105, 1984.
    • (1984) Endocrinology , vol.115 , pp. 102-105
    • Jarrousse, C.1    Bataille, D.2    Jeanrenaud, B.3
  • 28
    • 0028893424 scopus 로고
    • Evidence that glucagon stimulates insulin secretion through its own receptor in rats
    • Kawai K, Yokota C, Ohashi S, Watanabe Y, Yamashita K. Evidence that glucagon stimulates insulin secretion through its own receptor in rats. Diabetologia 38: 274-276, 1995.
    • (1995) Diabetologia , vol.38 , pp. 274-276
    • Kawai, K.1    Yokota, C.2    Ohashi, S.3    Watanabe, Y.4    Yamashita, K.5
  • 29
    • 0023160918 scopus 로고
    • Distribution of oxyntomodulin and glucagon in the gastrointestinal tract and the plasma of the rat
    • Kervran A, Blache P, Bataille D. Distribution of oxyntomodulin and glucagon in the gastrointestinal tract and the plasma of the rat. Endocrinology 121: 704-713, 1987.
    • (1987) Endocrinology , vol.121 , pp. 704-713
    • Kervran, A.1    Blache, P.2    Bataille, D.3
  • 31
    • 34249741098 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 gene therapy in obese diabetic mice results in long-term cure of diabetes by improving insulin sensitivity and reducing hepatic gluconeogenesis
    • Lee YS, Shin S, Shigihara T, Hahm E, Liu MJ, Han J, Yoon JW, Jun HS. Glucagon-like peptide-1 gene therapy in obese diabetic mice results in long-term cure of diabetes by improving insulin sensitivity and reducing hepatic gluconeogenesis. Diabetes 56: 1671-1679, 2007.
    • (2007) Diabetes , vol.56 , pp. 1671-1679
    • Lee, Y.S.1    Shin, S.2    Shigihara, T.3    Hahm, E.4    Liu, M.J.5    Han, J.6    Yoon, J.W.7    Jun, H.S.8
  • 32
    • 0025100958 scopus 로고
    • Glucagon and related peptides in fetal rat hypothalamus in vivo and in vitro
    • Lui EY, Asa SL, Drucker DJ, Lee YC, Brubaker PL. Glucagon and related peptides in fetal rat hypothalamus in vivo and in vitro. Endocrinology 126: 110-117, 1990.
    • (1990) Endocrinology , vol.126 , pp. 110-117
    • Lui, E.Y.1    Asa, S.L.2    Drucker, D.J.3    Lee, Y.C.4    Brubaker, P.L.5
  • 33
    • 0031965605 scopus 로고    scopus 로고
    • Dual glucagon recognition by pancreatic beta-cells via glucagon and glucagon-like peptide 1 receptors
    • Moens K, Flamez D, Van Schravendijk C, Ling Z, Pipeleers D, Schuit F. Dual glucagon recognition by pancreatic beta-cells via glucagon and glucagon-like peptide 1 receptors. Diabetes 47: 66-72, 1998.
    • (1998) Diabetes , vol.47 , pp. 66-72
    • Moens, K.1    Flamez, D.2    Van Schravendijk, C.3    Ling, Z.4    Pipeleers, D.5    Schuit, F.6
  • 34
    • 13344293675 scopus 로고    scopus 로고
    • Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells
    • Moens K, Heimberg H, Flamez D, Huypens P, Quartier E, Ling Z, Pipeleers D, Gremlich S, Thorens B, Schuit F. Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells. Diabetes 45: 257-261, 1996.
    • (1996) Diabetes , vol.45 , pp. 257-261
    • Moens, K.1    Heimberg, H.2    Flamez, D.3    Huypens, P.4    Quartier, E.5    Ling, Z.6    Pipeleers, D.7    Gremlich, S.8    Thorens, B.9    Schuit, F.10
  • 35
    • 0023008693 scopus 로고
    • Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing
    • Mojsov S, Heinrich G, Wilson IB, Ravazzola M, Orci L, Habener JF. Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing. J Biol Chem 261: 11880-11889, 1986.
    • (1986) J Biol Chem , vol.261 , pp. 11880-11889
    • Mojsov, S.1    Heinrich, G.2    Wilson, I.B.3    Ravazzola, M.4    Orci, L.5    Habener, J.F.6
  • 36
    • 0027419106 scopus 로고
    • Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at nearphysiological insulinotropic hormone and glucose concentrations
    • Nauck MA, Bartels E, Orskov C, Ebert R, Creutzfeldt W. Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at nearphysiological insulinotropic hormone and glucose concentrations. J Clin Endocrinol Metab 76: 912-917, 1993.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 912-917
    • Nauck, M.A.1    Bartels, E.2    Orskov, C.3    Ebert, R.4    Creutzfeldt, W.5
  • 37
    • 4544306391 scopus 로고    scopus 로고
    • Insulin and its evolving partnership with leptin in the hypothalamic control of energy homeostasis
    • Niswender KD, Baskin DG, Schwartz MW. Insulin and its evolving partnership with leptin in the hypothalamic control of energy homeostasis. Trends Endocrinol Metab 15: 362-369, 2004.
    • (2004) Trends Endocrinol Metab , vol.15 , pp. 362-369
    • Niswender, K.D.1    Baskin, D.G.2    Schwartz, M.W.3
  • 39
    • 0025376250 scopus 로고
    • Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats
    • Rossetti L, Giaccari A. Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats. J Clin Invest 85: 1785-1792, 1990.
    • (1990) J Clin Invest , vol.85 , pp. 1785-1792
    • Rossetti, L.1    Giaccari, A.2
  • 43
    • 0035514162 scopus 로고    scopus 로고
    • In muscle-specific lipoprotein lipase-overexpressing mice, muscle triglyceride content is increased without inhibition of insulin-stimulated whole-body and muscle-specific glucose uptake
    • Voshol PJ, Jong MC, Dahlmans VE, Kratky D, Levak-Frank S, Zechner R, Romijn JA, Havekes LM. In muscle-specific lipoprotein lipase-overexpressing mice, muscle triglyceride content is increased without inhibition of insulin-stimulated whole-body and muscle-specific glucose uptake. Diabetes 50: 2585-2590, 2001.
    • (2001) Diabetes , vol.50 , pp. 2585-2590
    • Voshol, P.J.1    Jong, M.C.2    Dahlmans, V.E.3    Kratky, D.4    Levak-Frank, S.5    Zechner, R.6    Romijn, J.A.7    Havekes, L.M.8
  • 44
    • 0037204861 scopus 로고    scopus 로고
    • Peripheral ghrelin selectively increases Fos expression in neuropeptide Y-synthesizing neurons in mouse hypothalamic arcuate nucleus
    • Wang L, Saint-Pierre DH, Taché Y. Peripheral ghrelin selectively increases Fos expression in neuropeptide Y-synthesizing neurons in mouse hypothalamic arcuate nucleus. Neurosci Lett 325: 47-51, 2002.
    • (2002) Neurosci Lett , vol.325 , pp. 47-51
    • Wang, L.1    Saint-Pierre, D.H.2    Taché, Y.3
  • 45
    • 33644840217 scopus 로고    scopus 로고
    • Rethinking leptin and insulin action: Therapeutic opportunities for diabetes
    • Yildiz BO, Haznedaroglu IC. Rethinking leptin and insulin action: therapeutic opportunities for diabetes. Int J Biochem Cell Biol 38: 820-830, 2006.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 820-830
    • Yildiz, B.O.1    Haznedaroglu, I.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.