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Volumn 48, Issue 10, 2005, Pages 2140-2146

Reduced insulin clearance contributes to the increased insulin levels after administration of glucagon-like peptide 1 in mice

Author keywords

C peptide kinetics; GLP 1; Glucagon like peptide 1; Insulin clearance; Insulin secretion; IVGTT; Mathematical modelling; Population modelling

Indexed keywords

C PEPTIDE; GLUCAGON LIKE PEPTIDE 1;

EID: 26244438849     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-005-1915-z     Document Type: Article
Times cited : (46)

References (21)
  • 1
    • 0021247256 scopus 로고
    • C-peptide as a measure of the secretion and hepatic extraction of insulin. Pitfalls and limitations
    • Polonsky KS, Rubenstein H (1984) C-peptide as a measure of the secretion and hepatic extraction of insulin. Pitfalls and limitations. Diabetes 33:486-494
    • (1984) Diabetes , vol.33 , pp. 486-494
    • Polonsky, K.S.1    Rubenstein, H.2
  • 3
    • 0015864034 scopus 로고
    • A comparative study on the metabolism of human insulin and porcine proinsulin in man
    • Sonksen PH, Tompkins CV, Srivastava MC, Nabarro JD (1973) A comparative study on the metabolism of human insulin and porcine proinsulin in man. Clin Sci Mol Med 45:633-654
    • (1973) Clin Sci Mol Med , vol.45 , pp. 633-654
    • Sonksen, P.H.1    Tompkins, C.V.2    Srivastava, M.C.3    Nabarro, J.D.4
  • 4
    • 0021864130 scopus 로고
    • New developments in the incretin concept
    • Creutzfeldt W, Ebert R (1985) New developments in the incretin concept. Diabetologia 28:565-573
    • (1985) Diabetologia , vol.28 , pp. 565-573
    • Creutzfeldt, W.1    Ebert, R.2
  • 5
    • 0020549057 scopus 로고
    • Discrepancy between plasma C-peptide and insulin response to oral and intravenous glucose
    • Madsbad S, Kehlet H, Hilsted J, Tronier B (1983) Discrepancy between plasma C-peptide and insulin response to oral and intravenous glucose. Diabetes 32:436-438
    • (1983) Diabetes , vol.32 , pp. 436-438
    • Madsbad, S.1    Kehlet, H.2    Hilsted, J.3    Tronier, B.4
  • 6
    • 0022518180 scopus 로고
    • Insulin and C-peptide levels after oral and intravenous glucose. Contribution of enteroinsular axis to insulin secretion
    • Hampton SM, Morgan LM, Tredger JA, Cramb R, Marks V (1986) Insulin and C-peptide levels after oral and intravenous glucose. Contribution of enteroinsular axis to insulin secretion. Diabetes 35:612-616
    • (1986) Diabetes , vol.35 , pp. 612-616
    • Hampton, S.M.1    Morgan, L.M.2    Tredger, J.A.3    Cramb, R.4    Marks, V.5
  • 7
    • 0023836241 scopus 로고
    • Incretin effect due to increased secretion and decreased clearance of insulin in normal humans
    • Shuster LT, Go VLW, Rizza RA, O'Brien PC, Service FJ (1988) Incretin effect due to increased secretion and decreased clearance of insulin in normal humans. Diabetes 37:200-203
    • (1988) Diabetes , vol.37 , pp. 200-203
    • Shuster, L.T.1    Go, V.L.W.2    Rizza, R.A.3    O'Brien, P.C.4    Service, F.J.5
  • 8
    • 0023610818 scopus 로고
    • Effect of intestinal factors on extraction of insulin in perfused rat livers
    • Ikeda T, Yoshida T, Honda M et al (1987) Effect of intestinal factors on extraction of insulin in perfused rat livers. Am J Physiol 253:E603-E607
    • (1987) Am J Physiol , vol.253
    • Ikeda, T.1    Yoshida, T.2    Honda, M.3
  • 9
    • 3242730474 scopus 로고    scopus 로고
    • Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans
    • Holst JJ, Gromada J (2004) Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans. Am J Physiol 287:E199-E206
    • (2004) Am J Physiol , vol.287
    • Holst, J.J.1    Gromada, J.2
  • 10
    • 4344675057 scopus 로고    scopus 로고
    • Therapeutic strategies based on glucagon-like peptide-1
    • Deacon CF (2004) Therapeutic strategies based on glucagon-like peptide-1. Diabetes 53:2181-2189
    • (2004) Diabetes , vol.53 , pp. 2181-2189
    • Deacon, C.F.1
  • 11
    • 12244275009 scopus 로고    scopus 로고
    • GLP-1 receptor agonists and DPP-4 inhibitors in the treatment of type 2 diabetes
    • Ahrén B, Schmitz O (2004) GLP-1 receptor agonists and DPP-4 inhibitors in the treatment of type 2 diabetes. Horm Metab Res 36:867-876
    • (2004) Horm Metab Res , vol.36 , pp. 867-876
    • Ahrén, B.1    Schmitz, O.2
  • 12
    • 0033864392 scopus 로고    scopus 로고
    • PACAP contributes to insulin secretion after gastric glucose gavage in mice
    • Filipsson K, Holst JJ, Ahrén B (2000) PACAP contributes to insulin secretion after gastric glucose gavage in mice. Am J Physiol 279:R424-R432
    • (2000) Am J Physiol , vol.279
    • Filipsson, K.1    Holst, J.J.2    Ahrén, B.3
  • 13
    • 0033381349 scopus 로고    scopus 로고
    • Dose-related effects of GLP-1 on insulin secretion, insulin sensitivity, and glucose effectiveness in mice
    • Ahrén B, Pacini G (1999) Dose-related effects of GLP-1 on insulin secretion, insulin sensitivity, and glucose effectiveness in mice. Am J Physiol 277:E996-E1004
    • (1999) Am J Physiol , vol.277
    • Ahrén, B.1    Pacini, G.2
  • 14
    • 0034796238 scopus 로고    scopus 로고
    • Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice
    • Pacini G, Thomaseth K, Ahrén B (2001) Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice. Am J Physiol 281:E693-E703
    • (2001) Am J Physiol , vol.281
    • Pacini, G.1    Thomaseth, K.2    Ahrén, B.3
  • 18
    • 0026504160 scopus 로고
    • Estimation of insulin secretion rates from C-peptide levels. Comparisons of individual and standard kinetic parameters for C-peptide clearance
    • Van Cauter E, Mestrez F, Sturis J, Polonsky KS (1992) Estimation of insulin secretion rates from C-peptide levels. Comparisons of individual and standard kinetic parameters for C-peptide clearance. Diabetes 41:368-377
    • (1992) Diabetes , vol.41 , pp. 368-377
    • Van Cauter, E.1    Mestrez, F.2    Sturis, J.3    Polonsky, K.S.4
  • 19
    • 0029963198 scopus 로고    scopus 로고
    • Integrated mathematical model to assess beta-cell activity during the oral glucose test
    • Thomaseth K, Kautzky-Willer A, Ludvik B, Prager R, Pacini G (1996) Integrated mathematical model to assess beta-cell activity during the oral glucose test. Am J Physiol 270:E522-E531
    • (1996) Am J Physiol , vol.270
    • Thomaseth, K.1    Kautzky-Willer, A.2    Ludvik, B.3    Prager, R.4    Pacini, G.5
  • 20
    • 0022572232 scopus 로고
    • Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type 1 diabetic patients
    • Polonsky KS, Linicio-Paixao J, Given BD et al (1986) Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type 1 diabetic patients. J Clin Invest 77:98-105
    • (1986) J Clin Invest , vol.77 , pp. 98-105
    • Polonsky, K.S.1    Linicio-Paixao, J.2    Given, B.D.3
  • 21
    • 0034088142 scopus 로고    scopus 로고
    • Accurate measurement of endogenous insulin secretion does not require separate assessment of C-peptide kinetics
    • Watanabe RM, Bergman RN (2000) Accurate measurement of endogenous insulin secretion does not require separate assessment of C-peptide kinetics. Diabetes 49:332-373
    • (2000) Diabetes , vol.49 , pp. 332-373
    • Watanabe, R.M.1    Bergman, R.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.