Poly (ADP-ribose) polymerase as a potential target for the treatment of acute renal injury caused by lipopolysaccharide

Renal Failure

Volumn 30, Issue 1, 2008, Pages 115-120

  Tasatargil, Arda ^a   Aksoy, Nazif Hikmet ^b   Dalaklioglu, Selvinaz ^c   Sadan, Gulay ^a  

^a AKDENIZ UNIVERSITY   (Turkey)

^b Anadolu Hastanesi Antalya   (Turkey)

^c Memorial Antalya Hospital   (Turkey)

Author keywords

Acute renal injury; Lipopolysaccharide; Poly(ADP ribose) polymerase; Rat

Indexed keywords

CREATININE; LIPOPOLYSACCHARIDE; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; N ACETYL BETA GLUCOSAMINIDASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; UREA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOTOXEMIA; HISTOPATHOLOGY; KIDNEY INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; URINARY EXCRETION; URINE LEVEL;

ACETYLGLUCOSAMINIDASE; ANIMALS; BLOOD UREA NITROGEN; CREATININE; ENDOTOXEMIA; ESCHERICHIA COLI; KIDNEY; KIDNEY FAILURE, ACUTE; LIPOPOLYSACCHARIDES; MALE; PHENANTHRENES; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, WISTAR;

EID: 38149101022     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.1080/08860220701742195     Document Type: Article

References (44)

1. Andreoli SP. Acute renal failure. Curr. Opin. Pediatr. 2002;14:183-188.
2. Anlatici R, Ozerdem OR, Dalay C, et al. A retrospective analysis of 1083 Turkish patients with serious burns, Part 2: Burn care, survival and mortality. Burns. 2002;28:239-243.
3. Berger NA. Poly(ADP-ribose) in the cellular response to DNA damage. Radic. Res. 1985;101:4-15.
4. Bone RC, Grodzin CJ, Balk RA. Sepsis: A new hypothesis for pathogenesis of the disease process. Chest. 1997;112:235-243.
5. Bonventre V. Mechanisms of ischemic acute renal failure. Kidney Int. 1993;43:1160-1178.
6. Chatterjee PK, Chatterjee BE, Pedersen H, et al. 5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/ reperfusion. Kidney Int. 2004;65:499-509.
7. Chiarugi A, Moskowitz MA. Cell biology PARP-1 - a perpetrator of apoptotic cell death? Science. 2002;297:200-201.
8. Chien CT, Lee PH, Chen CF, Ma MC, Lai MK, Hsu SM. De novo demonstration and co-localization of free-radical production and apoptosis formation in rat kidney subjected to ischemia/reperfusion. J Am Soc Nephrol. 2001;12:973-982.
9. Cohen J. The immunopathogenesis of sepsis. Nature. 2002;420:885-891.
10. Crow P, Beckman JS. Reactions between nitric oxide, superoxide, and peroxynitrite: Footprints of peroxynitrite in vivo. Adv. Pharmacol. 1995;34:17-43.
11. Devalaraja-Narashimha K, Singaravelu K, Padanilam BJ. Poly(ADP-ribose) polymerase-mediated cell injury in acute renal failure. Pharmacol. Res. 2005;52:44-59.
12. Eliasson MJ, Sampei K, Mandir AS, et al. Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nat. Med. 1997;3:1089-1095.
13. Garcia Soriano F, Virag L, Jagtap P, et al. Diabetic endothelial dysfunction: The role of poly (ADP-ribose) polymerase activation. Nat. Med. 2001;7:108-113.
14. Harlan JM. Neutrophil-mediated vascular injury. Acta Med. Scan. 1987; 715 (Suppl.): 123-129.
15. Hassa PO, Hottiger MO. The functional role of poly(ADPribose) polymerase 1 as novel coactivator of NF-kappaB in inflammatory disorders. Cell Mol. Life Sci. 2002;59:1534-1553.
16. Holm C, Horbrand F, von Donnersmarck GH, et al. Acute renal failure in severely burned patients. Burns. 1999;25:171-178.
17. Hotchkiss RS, Karl IE. The pathophysiology and treatment of sepsis. N Engl J Med. 2003;348:138-150.
18. Kadkhodaee M, Qasemi A. Inhibition of inducible nitric oxide synthase reduces lipopolysaccharide-induced renal injury in the rat. Clin Exp Pharmacol Physiol. 2004;31:842-846.
19. Kang HK, Kim DK, Lee BH et al. Urinary N-acetyl-β-D-glucosaminidase and malondialdehyde as markers of renal damage in burned patients. J Kor Med Sci. 2001;16:598-602.
20. Le Page C, Sanceau J, Drapier JC, Wietzerbin J. Inhibitors of ADP-ribosylation impair inducible nitric oxide synthase gene transcription through inhibition of NF kappa B activation. Biochem Biophys Res Commun. 1998;243:451-457.
21. Liaudet L, Soriano FG, Szabo E, et al. Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose) polymerase. Proc Natl Acad Sci USA. 2000;97:10203-10208.
22. Mabley JG, Jagtap P, Perretti M, et al. Anti-inflammatory effects of a novel, potent inhibitor of poly(ADP-ribose) polymerase. Inflamm Res. 2001;50:561-569.
23. Martin DR, Lewington AJ, Hammerman MR, Padanilam BJ. Inhibition of poly(ADP-ribose) polymerase attenuates ischemic renal injury in rats. Am J Physiol Regul Integr Comp Physiol. 2000;279:R1834-R1840.
24. Mayeux PR. Pathobiology of lipopolysaccharide. J Toxicol Environ Health. 1997;51:415-435.
25. McDonald MC, Mota-Filipe H, Wright JA, et al. Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase on the organ injury and dysfunction caused by hemorrhagic shock. Br J Pharmacol. 2000;130:843-850.
26. Millar CGM, Thiemermann C. Intrarenal hemodynamics and renal dysfunction in endotoxemia: Effects of nitric oxide synthase inhibition. Br J Pharmacol. 1997;121:1824-1830.
27. Mohaupt MG, Elzie JL, Ahn KY, Clapp WL, Wilcox CS, Kone BC. Differential expression and induction of mRNAs encoding two inducible nitric oxide synthases in rat kidney. Kidney Int. 1994;46:653-665.
28. Oliver FJ, Menissier-de Murcia J, Nacci C, et al. Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice. EMBO J. 1999;18:4446-4454.
29. O'Valle F, Benitez MC, Gomez-Morales M, et al. Role of poly-(ADP-ribose) polymerase in transplant acute tubular necrosis and its relationship with delayed renal function. Transplant Proc. 2005;37:1421-1423.
30. Jung K, Pergande M, Schimke E, Ratzmann KP, Luis A. Urinary enzymes and low molecular mass proteins as indicators of diabetic nephropathy. Clin. Chem. 1988;34:544-547.
31. Bosomworth MP, Aparicio SR, Hay AWM. Urine N-acetyl-beta- D-glucosaminidase: A marker of tubular damage? Nephrol Dial Transplant. 1999;14:620-626.
32. Salem MA, el-Habashy SA, Saeid OM, el-Tawil MM, Tawfik PH. Urinary excretion of N-acetyl-beta-D-glucosaminidase and retinol binding protein as alternative indicators of nephropathy in patients with type 1 diabetes mellitus. Pediatr Diabetes. 2002;3:37-41.
33. Pacher P, Liaudet L, Bai P, et al. Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure. J Pharmacol Exp Ther. 2002;300:862-867.
34. Piepot HA, Boer C, Groeneveld AB, Van Lambalgen AA, Sipkema P. Lipopolysaccharide impairs endothelial nitric oxide synthesis in rat renal arteries. Kidney Int. 2000;57:2502-2510.
35. Pryor WA, Squadrito GL. The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide. Am J Physiol. 1995;268:L699-L722.
36. Riedemann NC, Guo RF, Ward PA. Novel strategies for the treatment of sepsis. Nat Med. 2003;9:517-524.
37. Schraufstatter IU, Hinshaw DB, Hyslop PA, Spragg RG, Cochrane CG. DNA strand breaks activate poly adenosine diphosphate-ribose polymerase and leads to depletion of nicotinamide adenine dinucleotide. J Clin Invest. 1986;77:1312-1320.
38. Schwartz D, Brasowski E, Raskin Y, et al. The outcome of non-selective vs selective nitric oxide synthase inhibition in LPS treated rats. J Nephrol. 2001;14:110-114.
39. Schwartz D, Mendonca M, Schwartz I, et al. Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats. J Clin Invest. 1997;100:439-448.
40. Tasatargil A, Dalaklioglu S, Sadan G. Inhibition of poly(ADP-ribose) polymerase prevents vascular hyporesponsiveness induced by lipopolysaccharide in isolated rat aorta. Pharmacol Res. 2005;51:581-586.
41. Szabo C, Zingarelli B, O'Connor M, Salzman AL. DNA strand breakage, activation of poly(ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite. Proc Natl Acad Sci USA. 1996;93:1753-1758.
42. Szabo C, Dawson VL. Role of poly (ADP-ribose) synthetase in inflammation and ischemia-reperfusion. Trends Pharmacol Sci. 1998;19:287-298.
43. Zhang C, Walker LM, Mayeux PR. Role of nitric oxide in lipopolysaccharide-induced oxidant stress in the rat kidney. Biochem Pharmacol. 2000;59:203-209.
44. Zingarelli B, Salzman AL, Szabo C. Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intracellular adhesion molecule-1 in myocardial ischemia/reperfusion injury. Circ Res. 1998;83:85-94.