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Volumn 103, Issue 1, 2008, Pages 162-181

Essential role of PSM/SH2-B variants in insulin receptor catalytic activation and the resulting cellular responses

Author keywords

Cell permeant peptide; Dimerization; Insulin action; Internal ligand; Metabolism; PH; Pro rich; SH2 B

Indexed keywords

CBL PROTEIN; GLUCOSE; GLYCOGEN SYNTHASE; GLYCOGEN SYNTHASE KINASE 3; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; PLECKSTRIN; PROTEIN KINASE B; PROTEIN SH2; PROTEIN SH2B; S6 KINASE; UNCLASSIFIED DRUG;

EID: 38149062582     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21397     Document Type: Article
Times cited : (12)

References (70)
  • 1
    • 0034872381 scopus 로고    scopus 로고
    • Functional effects of APS and SH2-B on insulin receptor signaling
    • Ahmed Z, Pillay TS. 2001. Functional effects of APS and SH2-B on insulin receptor signaling. Biochem Soc Trans 29:529-534.
    • (2001) Biochem Soc Trans , vol.29 , pp. 529-534
    • Ahmed, Z.1    Pillay, T.S.2
  • 2
    • 0037627342 scopus 로고    scopus 로고
    • Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signaling
    • Ahmed Z, Pillay TS. 2003. Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signaling. Biochem J 371:405-412.
    • (2003) Biochem J , vol.371 , pp. 405-412
    • Ahmed, Z.1    Pillay, T.S.2
  • 3
    • 0034625744 scopus 로고    scopus 로고
    • The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor
    • Ahmed Z, Smith BJ, Pillay TS. 2000. The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor. FEBS Lett 475:31-34.
    • (2000) FEBS Lett , vol.475 , pp. 31-34
    • Ahmed, Z.1    Smith, B.J.2    Pillay, T.S.3
  • 4
    • 2442686849 scopus 로고    scopus 로고
    • Primary and essential role of the adaptor protein APS for recruitment of both c-Cbl and its associated protein CAP in insulin signaling
    • Ahn MY, Katsanakis KD, Bheda F, Pillay TS. 2004. Primary and essential role of the adaptor protein APS for recruitment of both c-Cbl and its associated protein CAP in insulin signaling. J Biol Chem 279:21526-21532.
    • (2004) J Biol Chem , vol.279 , pp. 21526-21532
    • Ahn, M.Y.1    Katsanakis, K.D.2    Bheda, F.3    Pillay, T.S.4
  • 5
    • 0025254381 scopus 로고
    • Kinetics of insulin binding and kinase activity of the partially purified insulin receptor from human skeletal muscle
    • Bak JF, Handberg A, Beck-Nielsen H, Pedersen O. 1990. Kinetics of insulin binding and kinase activity of the partially purified insulin receptor from human skeletal muscle. Biochim Biophys Acta 1052:306-312.
    • (1990) Biochim Biophys Acta , vol.1052 , pp. 306-312
    • Bak, J.F.1    Handberg, A.2    Beck-Nielsen, H.3    Pedersen, O.4
  • 6
    • 0034124975 scopus 로고    scopus 로고
    • Role of the tyrosine kinase JAK2 in signal transduction by growth hormone
    • Carter-Su C, Rui L, Herrington J. 2000a. Role of the tyrosine kinase JAK2 in signal transduction by growth hormone. Pediatr Nephrol 14:550-557.
    • (2000) Pediatr Nephrol , vol.14 , pp. 550-557
    • Carter-Su, C.1    Rui, L.2    Herrington, J.3
  • 7
    • 0034501137 scopus 로고    scopus 로고
    • SH2-B and SIRP: JAK2 binding proteins that modulate the actions of growth hormone
    • Carter-Su C, Rui L, Stofega MR. 2000b. SH2-B and SIRP: JAK2 binding proteins that modulate the actions of growth hormone. Recent Prog Horm Res 55:293-311.
    • (2000) Recent Prog Horm Res , vol.55 , pp. 293-311
    • Carter-Su, C.1    Rui, L.2    Stofega, M.R.3
  • 8
    • 1942454214 scopus 로고    scopus 로고
    • Adapter protein SH2-B beta undergoes nucleocytoplasmic shuttling: Implications for nerve growth factor induction of neuronal differentiation
    • Chen L, Carter-Su C. 2004. Adapter protein SH2-B beta undergoes nucleocytoplasmic shuttling: Implications for nerve growth factor induction of neuronal differentiation. Mol Cell Biol 24:3633-3647.
    • (2004) Mol Cell Biol , vol.24 , pp. 3633-3647
    • Chen, L.1    Carter-Su, C.2
  • 9
    • 0141960274 scopus 로고    scopus 로고
    • Growth factor receptor-binding protein 10 (Grb10) as a partner of phosphatidylinositol 3-kinase in metabolic insulin action
    • Deng Y, Bhattacharya S, Swamy OR, Tandon R, Wang Y, Janda R, Riedel H. 2003. Growth factor receptor-binding protein 10 (Grb10) as a partner of phosphatidylinositol 3-kinase in metabolic insulin action. J Biol Chem 278:39311-39322.
    • (2003) J Biol Chem , vol.278 , pp. 39311-39322
    • Deng, Y.1    Bhattacharya, S.2    Swamy, O.R.3    Tandon, R.4    Wang, Y.5    Janda, R.6    Riedel, H.7
  • 10
    • 33846615130 scopus 로고    scopus 로고
    • PSM/SH2-B distributes selected mitogenic receptor signals to distinct components in the PI3-kinase and MAP kinase signaling pathways
    • Deng Y, Xu H, Riedel H. 2007. PSM/SH2-B distributes selected mitogenic receptor signals to distinct components in the PI3-kinase and MAP kinase signaling pathways. J Cell Biochem 100:557-573.
    • (2007) J Cell Biochem , vol.100 , pp. 557-573
    • Deng, Y.1    Xu, H.2    Riedel, H.3
  • 12
    • 0037155344 scopus 로고    scopus 로고
    • SH2-Bbeta is a Rac-binding protein that regulates cell motility
    • Diakonova M, Gunter DR, Herrington J, Carter-Su C. 2002. SH2-Bbeta is a Rac-binding protein that regulates cell motility. J Biol Chem 277:10669-10677.
    • (2002) J Biol Chem , vol.277 , pp. 10669-10677
    • Diakonova, M.1    Gunter, D.R.2    Herrington, J.3    Carter-Su, C.4
  • 13
    • 6344243617 scopus 로고    scopus 로고
    • SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin
    • Duan C, Li M, Rui L. 2004a. SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin. J Biol Chem 279:43684-43691.
    • (2004) J Biol Chem , vol.279 , pp. 43684-43691
    • Duan, C.1    Li, M.2    Rui, L.3
  • 14
    • 4344581405 scopus 로고    scopus 로고
    • Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance
    • Duan C, Yang H, White MF, Rui L. 2004b. Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance. Mol Cell Biol 24:7435-7443.
    • (2004) Mol Cell Biol , vol.24 , pp. 7435-7443
    • Duan, C.1    Yang, H.2    White, M.F.3    Rui, L.4
  • 15
    • 0034643439 scopus 로고    scopus 로고
    • Molecular dissection of TrkA signal transduction pathways mediating differentiation in human neuroblastoma cells
    • Eggert A, Ikegaki N, Liu X, Chou TT, Lee VM, Trojanowski JQ, Brodeur GM. 2000. Molecular dissection of TrkA signal transduction pathways mediating differentiation in human neuroblastoma cells. Oncogene 19:2043-2051.
    • (2000) Oncogene , vol.19 , pp. 2043-2051
    • Eggert, A.1    Ikegaki, N.2    Liu, X.3    Chou, T.T.4    Lee, V.M.5    Trojanowski, J.Q.6    Brodeur, G.M.7
  • 17
    • 33745890232 scopus 로고    scopus 로고
    • Structural basis for phosphotyrosine recognition by the Src homology-2 domains of the adapter proteins SH2-B and APS
    • Hu J, Hubbard SR. 2006. Structural basis for phosphotyrosine recognition by the Src homology-2 domains of the adapter proteins SH2-B and APS. J Mol Biol 361:69-79.
    • (2006) J Mol Biol , vol.361 , pp. 69-79
    • Hu, J.1    Hubbard, S.R.2
  • 18
    • 0029587597 scopus 로고
    • Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase
    • Huang X, Li Y, Tanaka K, Moore KG, Hayashi JI. 1995. Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA 92:11618-11622.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11618-11622
    • Huang, X.1    Li, Y.2    Tanaka, K.3    Moore, K.G.4    Hayashi, J.I.5
  • 19
    • 0034720476 scopus 로고    scopus 로고
    • Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins
    • Iseki M, Takaki S, Takatsu K. 2000. Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins. Biochem Biophys Res Commun 272:45-54.
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 45-54
    • Iseki, M.1    Takaki, S.2    Takatsu, K.3
  • 20
    • 33846853084 scopus 로고    scopus 로고
    • Jamshidi Y, Snieder H, Ge D, Spector TD, O'Dell SD. 2007. The SH2B gene is associated with serum leptin and body fat in normal female twins. Obesity (Silver Spring) 15:5-9.
    • Jamshidi Y, Snieder H, Ge D, Spector TD, O'Dell SD. 2007. The SH2B gene is associated with serum leptin and body fat in normal female twins. Obesity (Silver Spring) 15:5-9.
  • 21
    • 0842312945 scopus 로고    scopus 로고
    • Skeletal muscle cells and adipocytes differ in their reliance on TC10 and Rac for insulin-induced actin remodeling
    • JeBailey L, Rudich A, Huang X, Di Ciano-Oliveira C, Kapus A, Klip A. 2004. Skeletal muscle cells and adipocytes differ in their reliance on TC10 and Rac for insulin-induced actin remodeling. Mol Endocrinol 18:359-372.
    • (2004) Mol Endocrinol , vol.18 , pp. 359-372
    • JeBailey, L.1    Rudich, A.2    Huang, X.3    Di Ciano-Oliveira, C.4    Kapus, A.5    Klip, A.6
  • 22
    • 27844503543 scopus 로고    scopus 로고
    • Cross-talk between the two divergent insulin signaling pathways is revealed by the protein kinase B (Akt)-mediated phosphorylation of adapter protein APS on serine 588
    • Katsanakis KD, Pillay TS. 2005. Cross-talk between the two divergent insulin signaling pathways is revealed by the protein kinase B (Akt)-mediated phosphorylation of adapter protein APS on serine 588. J Biol Chem 280:37827-37832.
    • (2005) J Biol Chem , vol.280 , pp. 37827-37832
    • Katsanakis, K.D.1    Pillay, T.S.2
  • 23
    • 0034598995 scopus 로고    scopus 로고
    • Direct interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loop
    • Koch A, Mancini A, Stefan M, Niedenthal R, Niemann H, Tamura T. 2000. Direct interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loop. FEBS Lett 469:72-76.
    • (2000) FEBS Lett , vol.469 , pp. 72-76
    • Koch, A.1    Mancini, A.2    Stefan, M.3    Niedenthal, R.4    Niemann, H.5    Tamura, T.6
  • 24
    • 0037013284 scopus 로고    scopus 로고
    • Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation
    • Kong M, Wang CS, Donoghue DJ. 2002. Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation. J Biol Chem 277:15962-15970.
    • (2002) J Biol Chem , vol.277 , pp. 15962-15970
    • Kong, M.1    Wang, C.S.2    Donoghue, D.J.3
  • 25
    • 0032189383 scopus 로고    scopus 로고
    • SH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinase
    • Kotani K, Wilden P, Pillay TS. 1998. SH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinase. Biochem J 335(Pt 1):103-109.
    • (1998) Biochem J , vol.335 , Issue.PART 1 , pp. 103-109
    • Kotani, K.1    Wilden, P.2    Pillay, T.S.3
  • 26
    • 0842267299 scopus 로고    scopus 로고
    • Roles of a conserved family of adaptor proteins, Lnk, SH2-B, and APS, for mast cell development, growth, and functions: APS-deficiency causes augmented degranulation and reduced actin assembly
    • Kubo-Akashi C, Iseki M, Kwon SM, Takizawa H, Takatsu K, Takaki S. 2004. Roles of a conserved family of adaptor proteins, Lnk, SH2-B, and APS, for mast cell development, growth, and functions: APS-deficiency causes augmented degranulation and reduced actin assembly. Biochem Biophys Res Commun 315:356-362.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 356-362
    • Kubo-Akashi, C.1    Iseki, M.2    Kwon, S.M.3    Takizawa, H.4    Takatsu, K.5    Takaki, S.6
  • 28
    • 33747748126 scopus 로고    scopus 로고
    • Binding of SH2-B family members within a potential negative regulatory region maintains JAK2 in an active state
    • Kurzer JH, Saharinen P, Silvennoinen O, Carter-Su C. 2006. Binding of SH2-B family members within a potential negative regulatory region maintains JAK2 in an active state. Mol Cell Biol 26:6381-6394.
    • (2006) Mol Cell Biol , vol.26 , pp. 6381-6394
    • Kurzer, J.H.1    Saharinen, P.2    Silvennoinen, O.3    Carter-Su, C.4
  • 29
    • 0025738349 scopus 로고
    • Insulin receptors prepared with iodoacetamide show enhanced autophosphorylation and receptor kinase activity
    • Li CH, Moule ML, Yip CC. 1991. Insulin receptors prepared with iodoacetamide show enhanced autophosphorylation and receptor kinase activity. J Biol Chem 266:7051-7057.
    • (1991) J Biol Chem , vol.266 , pp. 7051-7057
    • Li, C.H.1    Moule, M.L.2    Yip, C.C.3
  • 30
    • 33645891474 scopus 로고    scopus 로고
    • Differential role of SH2-B and APS in regulating energy and glucose homeostasis
    • Li M, Ren D, Iseki M, Takaki S, Rui L. 2006. Differential role of SH2-B and APS in regulating energy and glucose homeostasis. Endocrinology 147:2163-2170.
    • (2006) Endocrinology , vol.147 , pp. 2163-2170
    • Li, M.1    Ren, D.2    Iseki, M.3    Takaki, S.4    Rui, L.5
  • 31
    • 33947369866 scopus 로고    scopus 로고
    • Identification of SH2B2{beta} as an Inhibitor for SH2B1- and SH2B2{alpha}-promoted JAK2 Activation and Insulin Signaling
    • Li M, Li Z, Morris DL, Rui L. 2007. Identification of SH2B2{beta} as an Inhibitor for SH2B1- and SH2B2{alpha}-promoted JAK2 Activation and Insulin Signaling. Endocrinology 148:1615-1621.
    • (2007) Endocrinology , vol.148 , pp. 1615-1621
    • Li, M.1    Li, Z.2    Morris, D.L.3    Rui, L.4
  • 32
    • 33845663497 scopus 로고    scopus 로고
    • SH2B1 (SH2-B) and JAK2: A multifunctional adaptor protein and kinase made for each other
    • Maures TJ, Kurzer JH, Carter-Su C. 2006. SH2B1 (SH2-B) and JAK2: A multifunctional adaptor protein and kinase made for each other. Trends Endocrinol Metab 18:38-45.
    • (2006) Trends Endocrinol Metab , vol.18 , pp. 38-45
    • Maures, T.J.1    Kurzer, J.H.2    Carter-Su, C.3
  • 33
    • 0032409588 scopus 로고    scopus 로고
    • Regulation of System A amino acid transport in L6 rat skeletal muscle cells by insulin, chemical, and hyperthermic stress
    • McDowell HE, Eyers PA, Hundal HS. 1998. Regulation of System A amino acid transport in L6 rat skeletal muscle cells by insulin, chemical, and hyperthermic stress. FEBS Lett 441:15-19.
    • (1998) FEBS Lett , vol.441 , pp. 15-19
    • McDowell, H.E.1    Eyers, P.A.2    Hundal, H.S.3
  • 35
    • 18844365063 scopus 로고    scopus 로고
    • Increased SH2-Bbeta content and membrane association in transgenic mice overexpressing GH
    • Miquet JG, Sotelo AI, Bartke A, Turyn D. 2005. Increased SH2-Bbeta content and membrane association in transgenic mice overexpressing GH. J Endocrinol 185:301-306.
    • (2005) J Endocrinol , vol.185 , pp. 301-306
    • Miquet, J.G.1    Sotelo, A.I.2    Bartke, A.3    Turyn, D.4
  • 36
    • 0033574585 scopus 로고    scopus 로고
    • Identification of the APS protein as a novel insulin receptor substrate
    • Moodie SA, Alleman-Sposeto J, Gustafson TA. 1999. Identification of the APS protein as a novel insulin receptor substrate. J Biol Chem 274:11186-11193.
    • (1999) J Biol Chem , vol.274 , pp. 11186-11193
    • Moodie, S.A.1    Alleman-Sposeto, J.2    Gustafson, T.A.3
  • 37
    • 0032726331 scopus 로고    scopus 로고
    • Alternative splicing, gene localization, and binding of SH2-B to the insulin receptor kinase domain
    • Nelms K, O'Neill TJ, Li S, Hubbard SR, Gustafson TA, Paul WE. 1999. Alternative splicing, gene localization, and binding of SH2-B to the insulin receptor kinase domain. Mamm Genome 10:1160-1167.
    • (1999) Mamm Genome , vol.10 , pp. 1160-1167
    • Nelms, K.1    O'Neill, T.J.2    Li, S.3    Hubbard, S.R.4    Gustafson, T.A.5    Paul, W.E.6
  • 39
    • 0037040991 scopus 로고    scopus 로고
    • SH2-B family members differentially regulate JAK family tyrosine kinases
    • O'Brien KB, O'Shea JJ, Carter-Su C. 2002. SH2-B family members differentially regulate JAK family tyrosine kinases. J Biol Chem 277:8673-8681.
    • (2002) J Biol Chem , vol.277 , pp. 8673-8681
    • O'Brien, K.B.1    O'Shea, J.J.2    Carter-Su, C.3
  • 40
    • 0038146905 scopus 로고    scopus 로고
    • YXXL motifs in SH2-Bbeta are phosphorylated by JAK2. JAK1, and platelet-derived growth factor receptor and are required for membrane ruffling
    • O'Brien KB, Argetsinger LS, Diakonova M, Carter-Su C. 2003. YXXL motifs in SH2-Bbeta are phosphorylated by JAK2. JAK1, and platelet-derived growth factor receptor and are required for membrane ruffling. J Biol Chem 278:11970-11978.
    • (2003) J Biol Chem , vol.278 , pp. 11970-11978
    • O'Brien, K.B.1    Argetsinger, L.S.2    Diakonova, M.3    Carter-Su, C.4
  • 42
    • 0028802599 scopus 로고
    • The yeast tribrid system-genetic detection of trans-phosphorylated ITAM-SH2-interactions
    • Osborne MA, Dalton S, Kochan JP. 1995. The yeast tribrid system-genetic detection of trans-phosphorylated ITAM-SH2-interactions. Biotechnology (NY) 13:1474-1478.
    • (1995) Biotechnology (NY) , vol.13 , pp. 1474-1478
    • Osborne, M.A.1    Dalton, S.2    Kochan, J.P.3
  • 43
    • 0035131695 scopus 로고    scopus 로고
    • SH2-B and APS are multimeric adapters that augment TrkA signaling
    • Qian X, Ginty DD. 2001. SH2-B and APS are multimeric adapters that augment TrkA signaling. Mol Cell Biol 21:1613-1620.
    • (2001) Mol Cell Biol , vol.21 , pp. 1613-1620
    • Qian, X.1    Ginty, D.D.2
  • 44
    • 0032418850 scopus 로고    scopus 로고
    • Identification and characterization of novel substrates of Trk receptors in developing neurons
    • Qian X, Riccio A, Zhang Y, Ginty DD. 1998. Identification and characterization of novel substrates of Trk receptors in developing neurons. Neuron 21:1017-1029.
    • (1998) Neuron , vol.21 , pp. 1017-1029
    • Qian, X.1    Riccio, A.2    Zhang, Y.3    Ginty, D.D.4
  • 45
    • 33846822094 scopus 로고    scopus 로고
    • Neuronal SH2B1 is essential for controlling energy and glucose homeostasis
    • Ren D, Zhou Y, Morris D, Li M, Li Z, Rui L. 2007. Neuronal SH2B1 is essential for controlling energy and glucose homeostasis. J Clin Invest 117:397-406.
    • (2007) J Clin Invest , vol.117 , pp. 397-406
    • Ren, D.1    Zhou, Y.2    Morris, D.3    Li, M.4    Li, Z.5    Rui, L.6
  • 46
    • 0031474386 scopus 로고    scopus 로고
    • Riedel H, Wang J, Hansen H, Yousaf N. 1997. PSM, an insulin-dependent, pro-rich, PH, SH2 domain containing partner of the insulin receptor. J Biochem (Tokyo) 122:1105-1113.
    • Riedel H, Wang J, Hansen H, Yousaf N. 1997. PSM, an insulin-dependent, pro-rich, PH, SH2 domain containing partner of the insulin receptor. J Biochem (Tokyo) 122:1105-1113.
  • 47
    • 0034610745 scopus 로고    scopus 로고
    • PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis
    • Riedel H, Yousaf N, Zhao Y, Dai H, Deng Y, Wang J. 2000. PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis. Oncogene 19:39-50.
    • (2000) Oncogene , vol.19 , pp. 39-50
    • Riedel, H.1    Yousaf, N.2    Zhao, Y.3    Dai, H.4    Deng, Y.5    Wang, J.6
  • 48
    • 0035811366 scopus 로고    scopus 로고
    • Lnk adaptor: Novel negative regulator of B cell lymphopoiesis
    • Rudd CE. 2001. Lnk adaptor: Novel negative regulator of B cell lymphopoiesis. Sci STKE 2001: PE1.
    • (2001) Sci STKE 2001
    • Rudd, C.E.1
  • 49
    • 0032516879 scopus 로고    scopus 로고
    • Platelet-derived growth factor (PDGF) stimulates the association of SH2-Bbeta with PDGF receptor and phosphorylation of SH2-Bbeta
    • Rui L, Carter-Su C. 1998. Platelet-derived growth factor (PDGF) stimulates the association of SH2-Bbeta with PDGF receptor and phosphorylation of SH2-Bbeta. J Biol Chem 273:21239-21245.
    • (1998) J Biol Chem , vol.273 , pp. 21239-21245
    • Rui, L.1    Carter-Su, C.2
  • 50
    • 0033594812 scopus 로고    scopus 로고
    • Identification of SH2-bbeta as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2
    • Rui L, Carter-Su C. 1999. Identification of SH2-bbeta as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2. Proc Natl Acad Sci USA 96:7172-7177.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7172-7177
    • Rui, L.1    Carter-Su, C.2
  • 51
    • 0030613545 scopus 로고    scopus 로고
    • Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling
    • Rui L, Mathews LS, Hotta K, Gustafson TA, Carter-Su C. 1997. Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling. Mol Cell Biol 17:6633-6644.
    • (1997) Mol Cell Biol , vol.17 , pp. 6633-6644
    • Rui, L.1    Mathews, L.S.2    Hotta, K.3    Gustafson, T.A.4    Carter-Su, C.5
  • 52
    • 0033543546 scopus 로고    scopus 로고
    • SH2-B, a membrane-associated adapter, is phosphorylated on multiple serines/threonines in response to nerve growth factor by kinases within the MEK/ERK cascade
    • Rui L, Herrington J, Carter-Su C. 1999. SH2-B, a membrane-associated adapter, is phosphorylated on multiple serines/threonines in response to nerve growth factor by kinases within the MEK/ERK cascade. J Biol Chem 274:26485-26492.
    • (1999) J Biol Chem , vol.274 , pp. 26485-26492
    • Rui, L.1    Herrington, J.2    Carter-Su, C.3
  • 53
    • 0034004130 scopus 로고    scopus 로고
    • Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bbeta
    • Rui L, Gunter DR, Herrington J, Carter-Su C. 2000. Differential binding to and regulation of JAK2 by the SH2 domain and N-terminal region of SH2-bbeta. Mol Cell Biol 20:3168-3177.
    • (2000) Mol Cell Biol , vol.20 , pp. 3168-3177
    • Rui, L.1    Gunter, D.R.2    Herrington, J.3    Carter-Su, C.4
  • 54
    • 0036470213 scopus 로고    scopus 로고
    • Insulin signaling pathways in time and space
    • Saltiel AR, Pessin JE. 2002. Insulin signaling pathways in time and space. Trends Cell Biol 12:65-71.
    • (2002) Trends Cell Biol , vol.12 , pp. 65-71
    • Saltiel, A.R.1    Pessin, J.E.2
  • 55
    • 0032540944 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase activity by adenovirus-mediated gene transfer and its effect on insulin action
    • Sharma PM, Egawa K, Huang Y, Martin JL, Huvar I, Boss GR, Olefsky JM. 1998. Inhibition of phosphatidylinositol 3-kinase activity by adenovirus-mediated gene transfer and its effect on insulin action. J Biol Chem 273:18528-18537.
    • (1998) J Biol Chem , vol.273 , pp. 18528-18537
    • Sharma, P.M.1    Egawa, K.2    Huang, Y.3    Martin, J.L.4    Huvar, I.5    Boss, G.R.6    Olefsky, J.M.7
  • 56
    • 10644294729 scopus 로고    scopus 로고
    • Requirements for pYXXM motifs in Cbl for binding to the p85 subunit of phosphatidylinositol 3-kinase and Crk, and activation of atypical protein kinase C and glucose transport during insulin action in 3T3/L1 adipocytes
    • Standaert ML, Sajan MP, Miura A, Bandyopadhyay G, Farese RV. 2004. Requirements for pYXXM motifs in Cbl for binding to the p85 subunit of phosphatidylinositol 3-kinase and Crk, and activation of atypical protein kinase C and glucose transport during insulin action in 3T3/L1 adipocytes. Biochemistry 43:15494-15502.
    • (2004) Biochemistry , vol.43 , pp. 15494-15502
    • Standaert, M.L.1    Sajan, M.P.2    Miura, A.3    Bandyopadhyay, G.4    Farese, R.V.5
  • 58
    • 0034637506 scopus 로고    scopus 로고
    • Autophosphorylation of the two C-terminal tyrosine residues Tyr1316 and Tyr1322 modulates the activity of the insulin receptor kinase in vitro
    • Tennagels N, Bergschneider E, Al-Hasani H, Klein HW. 2000. Autophosphorylation of the two C-terminal tyrosine residues Tyr1316 and Tyr1322 modulates the activity of the insulin receptor kinase in vitro. FEBS Lett 479:67-71.
    • (2000) FEBS Lett , vol.479 , pp. 67-71
    • Tennagels, N.1    Bergschneider, E.2    Al-Hasani, H.3    Klein, H.W.4
  • 60
    • 0035135318 scopus 로고    scopus 로고
    • Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5′-phosphatase catalytic activity
    • Wada T, Sasaoka T, Funaki M, Hori H, Murakami S, Ishiki M, Haruta T, Asano T, Ogawa W, Ishihara H, Kobayashi M. 2001. Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5′-phosphatase catalytic activity. Mol Cell Biol 21:1633-1646.
    • (2001) Mol Cell Biol , vol.21 , pp. 1633-1646
    • Wada, T.1    Sasaoka, T.2    Funaki, M.3    Hori, H.4    Murakami, S.5    Ishiki, M.6    Haruta, T.7    Asano, T.8    Ogawa, W.9    Ishihara, H.10    Kobayashi, M.11
  • 61
    • 13844256697 scopus 로고    scopus 로고
    • Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer
    • Wadia JS, Dowdy SF. 2005. Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer. Adv Drug Deliv Rev 57:579-596.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 579-596
    • Wadia, J.S.1    Dowdy, S.F.2
  • 62
    • 0032488916 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor and insulin receptor association with a Src homology-2 domain-containing putative adapter
    • Wang J, Riedel H. 1998. Insulin-like growth factor-I receptor and insulin receptor association with a Src homology-2 domain-containing putative adapter. J Biol Chem 273:3136-3139.
    • (1998) J Biol Chem , vol.273 , pp. 3136-3139
    • Wang, J.1    Riedel, H.2
  • 63
    • 0032784061 scopus 로고    scopus 로고
    • Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis
    • Wang J, Dai H, Yousaf N, Moussaif M, Deng Y, Boufelliga A, Swamy OR, Leone ME, Riedel H. 1999. Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis. Mol Cell Biol 19: 6217-6228.
    • (1999) Mol Cell Biol , vol.19 , pp. 6217-6228
    • Wang, J.1    Dai, H.2    Yousaf, N.3    Moussaif, M.4    Deng, Y.5    Boufelliga, A.6    Swamy, O.R.7    Leone, M.E.8    Riedel, H.9
  • 64
    • 0347683481 scopus 로고    scopus 로고
    • SH2-B is a positive regulator of nerve growth factor-mediated activation of the Akt/Forkhead pathway in PC12 cells
    • Wang X, Chen L, Maures TJ, Herrington J, Carter-Su C. 2004. SH2-B is a positive regulator of nerve growth factor-mediated activation of the Akt/Forkhead pathway in PC12 cells. J Biol Chem 279:133-141.
    • (2004) J Biol Chem , vol.279 , pp. 133-141
    • Wang, X.1    Chen, L.2    Maures, T.J.3    Herrington, J.4    Carter-Su, C.5
  • 65
    • 0021339433 scopus 로고
    • Kinetic properties and sites of autophosphorylation of the partially purified insulin receptor from hepatoma cells
    • White MF, Haring HU, Kasuga M, Kahn CR. 1984. Kinetic properties and sites of autophosphorylation of the partially purified insulin receptor from hepatoma cells. J Biol Chem 259:255-264.
    • (1984) J Biol Chem , vol.259 , pp. 255-264
    • White, M.F.1    Haring, H.U.2    Kasuga, M.3    Kahn, C.R.4
  • 66
    • 0028813922 scopus 로고
    • Activation of mitogen-activated protein kinase and phosphatidylinositol 3′-kinase is not sufficient for the hormonal stimulation of glucose uptake, lipogenesis, or glycogen synthesis in 3T3-L1 adipocytes
    • Wiese RJ, Mastick CC, Lazar DF, Saltiel AR. 1995. Activation of mitogen-activated protein kinase and phosphatidylinositol 3′-kinase is not sufficient for the hormonal stimulation of glucose uptake, lipogenesis, or glycogen synthesis in 3T3-L1 adipocytes. J Biol Chem 270:3442-3446.
    • (1995) J Biol Chem , vol.270 , pp. 3442-3446
    • Wiese, R.J.1    Mastick, C.C.2    Lazar, D.F.3    Saltiel, A.R.4
  • 67
    • 0030812414 scopus 로고    scopus 로고
    • Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation
    • Yokouchi M, Suzuki R, Masuhara M, Komiya S, Inoue A, Yoshimura A. 1997. Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation. Oncogene 15:7-15.
    • (1997) Oncogene , vol.15 , pp. 7-15
    • Yokouchi, M.1    Suzuki, R.2    Masuhara, M.3    Komiya, S.4    Inoue, A.5    Yoshimura, A.6
  • 69
    • 0035798534 scopus 로고    scopus 로고
    • Four PSM/SH2-B alternative splice variants and their differential roles in mitogenesis
    • Yousaf N, Deng Y, Kang Y, Riedel H. 2001. Four PSM/SH2-B alternative splice variants and their differential roles in mitogenesis. J Biol Chem 276:40940-40948.
    • (2001) J Biol Chem , vol.276 , pp. 40940-40948
    • Yousaf, N.1    Deng, Y.2    Kang, Y.3    Riedel, H.4


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