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1
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34547326642
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The extracellular matrix of the lung and its role in edema formation
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Recent review discussing the importance of the pulmonary ECM in the physiology of the lung and its modifications during mechanical ventilation
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Pelosi P, Rocco PR, Negrini D, Passi A. The extracellular matrix of the lung and its role in edema formation. An Acad Bras Cienc 2007; 79:285-297. Recent review discussing the importance of the pulmonary ECM in the physiology of the lung and its modifications during mechanical ventilation.
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An Acad Bras Cienc
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Pelosi, P.1
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Mechanisms of ventilatory induced lung injury
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Vlahakis N, Hubmayr R. Cellular stress failure in ventilator-injured lungs. Am J Respir Crit Care Med 2005; 171:1328-1342.
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Schultz MJ, Haitsma JJ, Slutsky AS, Gajic O. What tidal should be used in patients without acute lung injury? Anesthesiology 2007; 106:1226-1231. In this review the authors discussed the role of mechanical ventilation to determine VILI in patients without acute lung injury. They propose a different ventilatory setting to be used in patients with healthy lungs during general anaesthesia and in patients at risk of acute respiratory failure.
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Schultz MJ, Haitsma JJ, Slutsky AS, Gajic O. What tidal volumes should be used in patients without acute lung injury? Anesthesiology 2007; 106:1226-1231. In this review the authors discussed the role of mechanical ventilation to determine VILI in patients without acute lung injury. They propose a different ventilatory setting to be used in patients with healthy lungs during general anaesthesia and in patients at risk of acute respiratory failure.
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5
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6344221796
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Changing pattern of ventilator settings in patients without acute lung injury: Changes over 11 years in a single institution
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Wongsurakiat P, Pierson DJ, Rubenfeld GD. Changing pattern of ventilator settings in patients without acute lung injury: changes over 11 years in a single institution. Chest 2004; 126:1281-1291.
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Wongsurakiat, P.1
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Rubenfeld, G.D.3
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6
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Feedback and education improve physician compliance in use of lung-protective mechanical ventilation
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Wolthuis EK, Korevaar JC, Spronk P, et al. Feedback and education improve physician compliance in use of lung-protective mechanical ventilation. Intensive Care Med 2005; 31:540-546.
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Wolthuis, E.K.1
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Iozzo RV. Matrix proteoglycans: from molecular design to cellular function. Annu Rev Biochem 1998; 67:609-652.
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Roberts C, Wight T, Hascall V. Protoglycans. In: Crystal RG, West JB, Weibel ER, editors. The lung: scientific foundation. Philadelphia: Lippincott-Raven; 1997. pp. 757-767.
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Roberts, C.1
Wight, T.2
Protoglycans, H.V.3
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10
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33750977810
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SLRP interaction can protect collagen fibrils from cleavage by collagenases
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Geng Y, McQuillan D, Roughley PJ. SLRP interaction can protect collagen fibrils from cleavage by collagenases. Matrix Biol 2006; 25:484-491.
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Matrix Biol
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11
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Ruoslahti E, Yamaguchi Y. Proteoglycans as modulators of growth factor activities. Cell 1991; 64:867-869.
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Ruoslahti, E.1
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12
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27144468308
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Interaction of chemokines and glycosaminoglycans: A new twist in the regulation of chemokine function with opportunities for therapeutic intervention
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Johnson Z, Proudfoot AE, Handel TM. Interaction of chemokines and glycosaminoglycans: a new twist in the regulation of chemokine function with opportunities for therapeutic intervention. Cytokine Growth Factor Rev 2005; 16:625-636.
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Johnson, Z.1
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13
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Schaefer L, Babelova A, Kiss E, et al. The matrix component biglycan is proinflammatory and signals through toll-like receptors 4 and 2 in macrophages. J Clin Invest 2005; 115:2223-2233.
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Schaefer L, Babelova A, Kiss E, et al. The matrix component biglycan is proinflammatory and signals through toll-like receptors 4 and 2 in macrophages. J Clin Invest 2005; 115:2223-2233.
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14
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Extracellular matrix signaling through growth factor receptors during wound healing
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Tran KT, Griffith L, Wells A. Extracellular matrix signaling through growth factor receptors during wound healing. Wound Repair Regen 2004; 12:262-268.
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Wound Repair Regen
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Tran, K.T.1
Griffith, L.2
Wells, A.3
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15
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Decorin activates the epidermal growth factor receptor and elevates cytosolic ca2+ in a431 carcinoma cells
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Patel S, Santra M, McQuillan DJ, et al. Decorin activates the epidermal growth factor receptor and elevates cytosolic ca2+ in a431 carcinoma cells. J Biol Chem 1998; 273:3121-3124.
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Patel, S.1
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16
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Greenlee KJ, Werb Z, Kheradmand F. Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted. Physiol Rev 2007; 87:69-98. Excellent review discussing the role of metalloproteasis in the lung both from a biological and clinical point of view.
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Greenlee KJ, Werb Z, Kheradmand F. Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted. Physiol Rev 2007; 87:69-98. Excellent review discussing the role of metalloproteasis in the lung both from a biological and clinical point of view.
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17
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Elkington PT, Friedland JS. Matrix metalloproteinases in destructive pulmonary pathology. Thorax 2006; 61:259-266. This paper discuss the role of metalloproteasis in the remodelling process of the pulmonary parenchyma.
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Elkington PT, Friedland JS. Matrix metalloproteinases in destructive pulmonary pathology. Thorax 2006; 61:259-266. This paper discuss the role of metalloproteasis in the remodelling process of the pulmonary parenchyma.
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18
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3042653504
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Dependence of lung injury on inflation rate during low-volume ventilation in normal open-chest rabbits
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D'Angelo E, Pecchiari M, Saetta M, et al. Dependence of lung injury on inflation rate during low-volume ventilation in normal open-chest rabbits. J Appl Physiol 2004; 97:260-268.
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J Appl Physiol
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D'Angelo, E.1
Pecchiari, M.2
Saetta, M.3
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19
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Atalectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs
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Duggan M, Mc Caul C, Mc Namara P, et al. Atalectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs. Am J Respir Crit Care Med 2003; 167:1633-1640.
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Am J Respir Crit Care Med
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Duggan, M.1
Mc Caul, C.2
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20
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Low-volume ventilation causes peripheral airway injury and increased airway resistance in normal rabbits
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D'Angelo E, Pecchiari M, Baraggia M, et al. Low-volume ventilation causes peripheral airway injury and increased airway resistance in normal rabbits. J Appl Physiol 2002; 92:949-956.
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D'Angelo, E.1
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21
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Effects of mechanical ventilation at low lung volume on respiratory mechanics and nitric oxide exhalation in normal rabbits
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D'Angelo E, Pecchiari M, Della Valle P, et al. Effects of mechanical ventilation at low lung volume on respiratory mechanics and nitric oxide exhalation in normal rabbits. J Appl Physiol 2005; 99:433-444.
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D'Angelo, E.1
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22
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High lung inflation increases mRNA levels of ECM components and growth factors in lung parenchyma
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Berg JT, Fu Z, Breen EC, et al. High lung inflation increases mRNA levels of ECM components and growth factors in lung parenchyma. J Appl Physiol 1997; 83:120-128.
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Berg, J.T.1
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23
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Mechanical strain increases type I collagen expression in pulmonary fibroblasts in vitro
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Breen EC. Mechanical strain increases type I collagen expression in pulmonary fibroblasts in vitro. J Appl Physiol 2000; 88:203-209.
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Breen, E.C.1
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Changes in proteoglycans and lung tissue mechanics during excessive mechanical ventilation in rats
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Al Jamal R, Ludwig M. Changes in proteoglycans and lung tissue mechanics during excessive mechanical ventilation in rats. Am J Physiol Lung Cell Mol Physiol 2001; 281:L1078-L1087.
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Al Jamal, R.1
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25
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34548400707
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Proteoglycan fragmentation and respiratory mechanics in mechanically ventilated healthy rats
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This paper outlines the effects of mechanical ventilation on glycosaminoglycan fragmentation, suggesting that even ventilation at low tidal may injure the lung structures without any inflammatory-associated response
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Moriondo A, Pelosi P, Passi A, et al. Proteoglycan fragmentation and respiratory mechanics in mechanically ventilated healthy rats. J Appl Physiol 2007; 103:747-756. This paper outlines the effects of mechanical ventilation on glycosaminoglycan fragmentation, suggesting that even ventilation at low tidal volumes may injure the lung structures without any inflammatory-associated response.
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J Appl Physiol
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Moriondo, A.1
Pelosi, P.2
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26
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Production of inflammatory cytokines in ventilator induced lung injury: A reappraisal
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Ricard J, Dreyfuss D, Saumon G. Production of inflammatory cytokines in ventilator induced lung injury: a reappraisal. Am J Respir Crit Care Med 2001; 163:1176-1180.
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Ricard, J.1
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Saumon, G.3
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27
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Conventional mechanical ventilation of healthy lungs induced pro-inflammatory cytokine gene transcription
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Bregeon F, Roch A, Delpierre S, et al. Conventional mechanical ventilation of healthy lungs induced pro-inflammatory cytokine gene transcription. Respir Physiol Neurobiol 2002; 132:191-203.
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Bregeon, F.1
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28
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Positive end-expiratory pressure prevents lung mechanical stress caused by recruitment/derecruitment
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Farias LL, Faffe DS, Xisto DG, et al. Positive end-expiratory pressure prevents lung mechanical stress caused by recruitment/derecruitment. J Appl Physiol 2005; 98:53-61.
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J Appl Physiol
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Farias, L.L.1
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29
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Ventilator-induced lung injury without biotrauma?
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Hubmayr RD. Ventilator-induced lung injury without biotrauma? J Appl Physiol 2005; 99:384-385.
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J Appl Physiol
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Hubmayr, R.D.1
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30
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33744779424
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Early emphysema in the tight skin and pallid mice: Roles of microfibril-associated glycoproteins, collagen, and mechanical forces
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Ito S, Bartolak-Suki E, Shipley JM, et al. Early emphysema in the tight skin and pallid mice: roles of microfibril-associated glycoproteins, collagen, and mechanical forces. Am J Respir Cell Mol Biol 2006; 34:688-694.
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Am J Respir Cell Mol Biol
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Ito, S.1
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Shipley, J.M.3
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31
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Mechanics, nonlinearity, and failure strength of lung tissue in a mouse model of emphysema: Possible role of collagen remodeling
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Ito S, Ingenito EP, Brewer KK, et al. Mechanics, nonlinearity, and failure strength of lung tissue in a mouse model of emphysema: Possible role of collagen remodeling. J Appl Physiol 2005; 98:503-511.
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Ito, S.1
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Brewer, K.K.3
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32
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33846262518
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Differences in proteoglycan deposition in the airways of moderate and severe asthmatics
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This paper discusses the role of proteoglycans in asthma
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Pini L, Hamid Q, Shannon J, et al. Differences in proteoglycan deposition in the airways of moderate and severe asthmatics. Eur Respir J 2007; 29:71-77. This paper discusses the role of proteoglycans in asthma.
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Pini, L.1
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Shannon, J.3
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34
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Moriondo A, Mukenge S, Negrini D. Transmural pressure in rat initial subpleural lymphatics during spontaneous or mechanical ventilation. Am J Physiol Heart Circ Physiol 2006; 289:H263-H269. In this paper the authors investigated the effect of mechanical ventilation as compared with spontaneous breathing. They found that mechanical ventilation markedly reduced the driving pressure gradient between the interstitial space of the thoracic tissues and the lymphatic lumen, likely impeding the fluid egress of the lung parenchyma
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Moriondo A, Mukenge S, Negrini D. Transmural pressure in rat initial subpleural lymphatics during spontaneous or mechanical ventilation. Am J Physiol Heart Circ Physiol 2006; 289:H263-H269. In this paper the authors investigated the effect of mechanical ventilation as compared with spontaneous breathing. They found that mechanical ventilation markedly reduced the driving pressure gradient between the interstitial space of the thoracic tissues and the lymphatic lumen, likely impeding the fluid egress of the lung parenchyma.
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35
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Pelosi P, Rocco PR. Airway closure: the silent killer of peripheral airways. Crit Care 2007; 11:114.
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Pelosi, P.1
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36
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33746882111
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Intraoperative tidal volume as a risk factor for respiratory failure after pneumonectomy
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This study emphasizes the importance of an intraoperative ventilatory setting to prevent postoperative pulmonary complications. The authors found that the intraoperative reduction in tidal and fluid administration was associated with a reduction of postoperative pulmonary complications
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Fernandez-Perez ER, Keegan MT, Brown DR, et al. Intraoperative tidal volume as a risk factor for respiratory failure after pneumonectomy. Anesthesiology 2006; 105:14-18. This study emphasizes the importance of an intraoperative ventilatory setting to prevent postoperative pulmonary complications. The authors found that the intraoperative reduction in tidal volume and fluid administration was associated with a reduction of postoperative pulmonary complications.
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Anesthesiology
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Fernandez-Perez, E.R.1
Keegan, M.T.2
Brown, D.R.3
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Ventilation with lower tidal as compared with traditional tidal for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000; 342:1301-1308
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Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000; 342:1301-1308.
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39
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Mechanical ventilation strategies and inflammatory responses to cardiac surgery: A prospective randomized clinical trial
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Wrigge H, Uhlig U, Baumgarten G, et al. Mechanical ventilation strategies and inflammatory responses to cardiac surgery: a prospective randomized clinical trial. Intensive Care Med 2005; 31:1379-1387.
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Wrigge, H.1
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Zupanchich E, Paparella D, Turani F, et al. Mechanical ventilation affects inflammatory mediators in patients undergoing cardiopulmonary bypass for cardiac surgery: a randomized trial. J Thorac Cardiovasc Surg 2005; 130:378-383.
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Reis Miranda D, Gommers D, Struijs A, et al. Ventilation according to the open lung concept attenuates pulmonary inflammatory response in cardiac surgery. Eur J Cardiothorac Surg 2005; 28:889-895.
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42
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33749186344
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Choi G, Wolthuis EK, Bresser P, et al. Mechanical ventilation with lower tidal and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injury. Anesthesiology 2006; 105:689-695. This paper investigated the effects of protective ventilation, with low tidal and PEEP on lung injury in patients without lung injury. The authors found that protective ventilation may be beneficial in reducing postoperative lung injury.
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Choi G, Wolthuis EK, Bresser P, et al. Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injury. Anesthesiology 2006; 105:689-695. This paper investigated the effects of protective ventilation, with low tidal volume and PEEP on lung injury in patients without lung injury. The authors found that protective ventilation may be beneficial in reducing postoperative lung injury.
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43
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33750450886
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Michelet P, D'Journo XB, Roch A, et al. Protective ventilation influences systemic inflammation after esophagectomy: a randomized controlled study. Anesthesiology 2006; 105:911-919. In this paper the authors clearly demonstrated that in patients with healthy lungs undergoing high risk surgery, protective ventilation can be helpful to minimize VILI
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Michelet P, D'Journo XB, Roch A, et al. Protective ventilation influences systemic inflammation after esophagectomy: a randomized controlled study. Anesthesiology 2006; 105:911-919. In this paper the authors clearly demonstrated that in patients with healthy lungs undergoing high risk surgery, protective ventilation can be helpful to minimize VILI.
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44
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1342288561
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The effects of different ventilatory settings on pulmonary and systemic inflammatory responses during major surgery
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Wrigge H, Uhlig U, Zinserling J, et al. The effects of different ventilatory settings on pulmonary and systemic inflammatory responses during major surgery. Anesth Analg 2004; 98:775-781.
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Wrigge, H.1
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Effect of mechanical ventilation on release of cytokines into systemic circulation in patients with normal pulmonary function
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Wrigge H, Zinserling J, Stuber F, et al. Effect of mechanical ventilation on release of cytokines into systemic circulation in patients with normal pulmonary function. Anesthesiology 2000; 93:1413-1417.
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Effects of protective and conventional mechanical ventilation on pulmonary function and systemic cytokine release after cardiopulmonary bypass
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Koner O, Celebi S, Balci H, et al. Effects of protective and conventional mechanical ventilation on pulmonary function and systemic cytokine release after cardiopulmonary bypass. Intensive Care Med 2004; 30:620-626.
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