Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor

FASEB Journal

Volumn 22, Issue 1, 2008, Pages 295-306

  Franceschini, Stefano ^a   Ilari, Andrea ^a   Verzili, Daniela ^a   Zamparelli, Carlotta ^a   Antaramian, Anaid ^b   Rueda, Angélica ^b   Valdivia, Hector H ^b   Chiancone, Emilia ^a   Colotti, Gianni ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Calcium induced channel release; Channels; EF hand; Excitation contraction coupling; Heart; PEF proteins

Indexed keywords

CALCIUM CHANNEL; PROTEIN F112L; RYANODINE RECEPTOR; SORCIN; SYNEXIN; UNCLASSIFIED DRUG; CALCIUM; CALCIUM BINDING PROTEIN; PRIMER DNA; SRI PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CALCIUM BINDING; CALCIUM TRANSPORT; HYDROGEN BOND; MOLECULE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; HAMSTER; HUMAN; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN BINDING; PROTEIN CONFORMATION; RAT; SPRAGUE DAWLEY RAT; SURFACE PLASMON RESONANCE; ULTRACENTRIFUGATION;

MUS;

ANIMALS; ANNEXIN A7; BASE SEQUENCE; CALCIUM; CALCIUM-BINDING PROTEINS; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN CONFORMATION; RATS; RATS, SPRAGUE-DAWLEY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SURFACE PLASMON RESONANCE; ULTRACENTRIFUGATION;

EID: 38049177758     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-8988com     Document Type: Article

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