The W105G and W99G sorcin mutants demonstrate the role of the D helix in the Ca2+-dependent interaction with annexin VII and the cardiac ryanodine receptor

Biochemistry

Volumn 45, Issue 41, 2006, Pages 12519-12529

  Colotti, Gianni ^a   Zamparelli, Carlotta ^a   Verzili, Daniela ^a   Mella, Manuela ^a   Loughrey, Christopher M ^b,c   Smith, Godfrey L ^b   Chiancone, Emilia ^a,b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CALCIUM COMPOUNDS; MUTAGENESIS; SUBSTITUTION REACTIONS;

CALCIUM AFFINITY; SORCIN; TARGET PROTEINS;

PROTEINS;

CALCIUM BINDING PROTEIN; CALCIUM ION; GLYCINE; MUTANT PROTEIN; RYANODINE RECEPTOR; SORCIN; SYNEXIN; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CALCIUM BINDING; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HEART MUSCLE CELL; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SURFACE PLASMON RESONANCE; WILD TYPE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANNEXIN A7; BASE SEQUENCE; BINDING SITES; CALCIUM; CALCIUM-BINDING PROTEINS; CLONING, MOLECULAR; CRICETINAE; CRICETULUS; DNA, COMPLEMENTARY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MYOCARDIUM; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SURFACE PLASMON RESONANCE;

EID: 33750045984     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi060416a     Document Type: Article

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