Study of tea polyphenol as a reversal agent for carcinoma cell lines’ multidrug resistance (study of TP as a MDR reversal agent)

Nuclear Medicine and Biology

Volumn 28, Issue 6, 2001, Pages 735-740

  Zhu, Aizhi ^a   Wang, Xiangyun ^a   Guo, Zhenquan ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

99mTc tetrofosmin; Immunocytochemistry; MTT; P glycoprotein; Tea polyphenol

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTINEOPLASTIC AGENT; DOXORUBICIN; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; GLYCOPROTEIN P; POLYPHENOL DERIVATIVE; QUINIDINE; TEA POLYPHENOL; TETROFOSMIN TC 99M; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; BREAST ADENOCARCINOMA; CELL STRAIN MCF 7; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG SENSITIVITY; DRUG UPTAKE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INHIBITION KINETICS; MULTIDRUG RESISTANCE; PROTEIN EXPRESSION;

BREAST NEOPLASMS; DRUG INTERACTIONS; DRUG RESISTANCE, MULTIPLE; FLAVONOIDS; ORGANOPHOSPHORUS COMPOUNDS; ORGANOTECHNETIUM COMPOUNDS; P-GLYCOPROTEIN; PHENOLS; PLANT EXTRACTS; POLYMERS; QUINIDINE; TEA; TUMOR CELLS, CULTURED;

EID: 0034892126     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(00)90202-6     Document Type: Article

References (9)

1. Technetium-99m-tetrofosmin as a substrate for P-glycoprotein: In vitro studies in multidrug resistant breast tumor cells
2. Inhibition of the tobacco-specific nitrosamine-induced lung tumorigenesis by compounds derived from cruciferous vegetables and green tea
3. Pharmacology of drugs that alter multidrug resistance in cancer
4. Inhibitory effect of topical application of a green tea polyphenol fraction on tumor initiation and promotion in mouse skin
5. Involvement of protein tyrosine phophorylation in the effect of green tea polyphenols on Ehrlich ascites tumor cells in vitro
6. Modulation of the multidrug resistance P-glycoprotein: Detection with technetium-99m-sestamibi in vivo
7. Apoptosis of colon cancer cell line, LoVo, induced by green tea aqueous extract in vitro
8. Multidrug resistance from the clinical point of view