Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking

PLoS Medicine

Volumn 4, Issue 12, 2007, Pages 1993-2000

  Hughes, Anne E ^a   Orr, Nick ^a   Patterson, Chris ^a   Esfandiary, Hossein ^a   Hogg, Ruth ^a   McConnell, Vivienne ^a   Silvestri, Giuliana ^a   Chakravarthy, Usha ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT FACTOR H; DNA; ARMS2 PROTEIN, HUMAN; COMPLEMENT FACTOR H, HUMAN; HTRA1 PROTEIN, HUMAN; PROTEIN; SERINE PROTEINASE;

AGED; ARTICLE; CASE CONTROL STUDY; CFH GENE; CIGARETTE SMOKING; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HAPLOTYPE; HTRA1 GENE; HUMAN; LOC387715 GENE; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; PROMOTER REGION; RETINA MACULA AGE RELATED DEGENERATION; RETINA MACULA DEGENERATION; RISK ASSESSMENT; SCORING SYSTEM; SUBRETINAL NEOVASCULARIZATION; BIOLOGICAL MODEL; BLINDNESS; GENETIC PREDISPOSITION; GENETICS; HOMOZYGOTE; METHODOLOGY; MIDDLE AGED; PHENOTYPE; RISK; RISK FACTOR; SMOKING; STATISTICAL MODEL;

AGED; AGED, 80 AND OVER; BLINDNESS; CASE-CONTROL STUDIES; CHOROIDAL NEOVASCULARIZATION; COMPLEMENT FACTOR H; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HOMOZYGOTE; HUMANS; LOGISTIC MODELS; MACULAR DEGENERATION; MALE; MIDDLE AGED; MODELS, GENETIC; ODDS RATIO; PHENOTYPE; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; PROTEINS; RESEARCH DESIGN; RISK ASSESSMENT; RISK FACTORS; SERINE ENDOPEPTIDASES; SMOKING;

EID: 38049086708     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.0040355     Document Type: Article

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