Epinephrine inhibits analgesic tolerance to intrathecal administrated morphine and increases the expression of calcium-calmodulin-dependent protein kinase IIα

Neuroscience Letters

Volumn 430, Issue 3, 2008, Pages 213-217

  Satarian, Leila ^a   Javan, Mohammad ^a   Fathollahi, Yaghoub ^a  

^a TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

Calcium calmodulin dependent protein kinase II ; Epinephrine; Morphine; Opioids; Rats; Tolerance

Indexed keywords

ADRENALIN; MORPHINE; PROTEIN KINASE (CALCIUM,CALMODULIN) II;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; GENE SEQUENCE; MALE; MORPHINE TOLERANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADRENERGIC AGONISTS; ANALGESICS, OPIOID; ANIMALS; BRAIN; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; DRUG INTERACTIONS; DRUG TOLERANCE; ENZYME ACTIVATION; EPINEPHRINE; GENE EXPRESSION REGULATION; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INJECTIONS, SPINAL; MALE; MORPHINE; MORPHINE DEPENDENCE; RATS; RATS, WISTAR; RNA, MESSENGER; UP-REGULATION;

EID: 38049059767     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.10.038     Document Type: Article

References (37)

1. Alonso E., Garrido E., Di{dotless}ez-Fernandez C., Perez-Garci{dotless}a C., Herradon G., Ezquerra L., Deuel T.F., and Alguacil L.F. Yohimbine prevents morphine-induced changes of glial fibrillary acidic protein in brainstem and α2-adrenoceptor gene expression in hippocampus. Neurosci. Lett. 412 (2007) 163-167
2. Ausubel F.M., Brent R., Kingston R.E., Moore D.D., Seidman J.G., Smith J.A., and Struhl K. Short Protocols in Molecular Biology (2002), John Wiley and Sons Press, New York
3. Berne R.M., Levy M.N., Koeppen B.M., and Stanton B.A. Physiology. fifth ed. (2004), Mosby, Missouri
4. Blitzer R.D., Connor J.H., Brown G.P., Wong T., Shenolikar S., Iyengar R., and Landau E.M. Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP. Science 280 (1998) 1940-1942
5. Braun A.P., and Schulman H. The multifunctional calcium/calmodulin dependent protein kinase: from form to function. Ann. Rev. Physiol. 57 (1995) 417-445
6. Burd A.L., EI-Kouhen R., Erickson H., Loh L.I., and Law P.Y. Identification of serine 356 and 363 as the amino acids involved in etorphine induced down-regulation of the mu-opioid receptor. J. Biol. Chem. 273 (1998) 34488-34495
7. Bruggemann I., Schulz S., Wiborny D., and Hollt V. Colocalization of the mu-opioid receptor and calcium/calmodulin-dependent kinase II in distinct pain-processing brain regions. Brain Res. Mol. Brain Res. 85 (2000) 239-250
8. Chakrabarti S., Wang L., Tang W.J., and Gintzler R.A. Chronic morphine augments adenylyl cyclase phosphorylation: relevance to altered signaling during tolerance/dependence. Mol. Pharmacol. 54 (1998) 949-953
9. Colpaert F.C., Nuenegeers C.R.E., Jansen P.A.J., and Maroli A.N. The effects of prior fentanyl administration and pain on fentanyl administration: tolerance to and enhancement of narcotic analgesia. J. Pharmacol. Exp. Ther. 213 (1980) 418-426
10. D'Amour F.E., and Smith D.L. A method for determining loss of pain sensation. J. Pharmacol. Exp. Ther. 72 (1941) 74-79
11. Fan G.H., Wang L.Z., Qiu H.C., Ma L., and Pei G. Inhibition of calcium/calmodulin-dependent protein kinase II in rat hippocampus attenuates morphine tolerance and dependence. Mol. Pharmacol. 56 (1999) 39-45
12. Hanson P.I., and Schulman H. Neuronal Ca2+/calmodulin-dependent protein kinases. Ann. Rev. Biochem 61 (1992) 559-601
13. Hendrie C.A. ACTH: a single pretreatment enhances the analgesic efficiency of and prevents the development of tolerance to morphine. Physiol. Behav. 42 (1988) 41-45
14. Javan M., Ahmadiani A., Motamedi F., and Kazemi B. Changes in G proteins genes expression in rat lumbar spinal cord support the inhibitory effect of chronic pain on the development of tolerance to morphine analgesia. Neurosci. Res. 53 (2005) 250-256
15. Javan M., Kazemi B., Ahmadiani A., and Motamedi F. Dexamethasone mimics the inhibitory effect of chronic pain on the development of tolerance to morphine analgesia and compensates for morphine induced changes in g proteins gene expression. Brain Res. 1104 (2006) 73-79
16. Kamisaki Y., Hamada T., Maeda K., Ishimura M., and Itoh T. Presynaptic alpha-2 adrenoreceptors inhibit glutamate release from rat spinal cord synaptosomes. J. Neurochem. 60 (1993) 522-529
17. Kennedy M.B. Signal-processing machines at the postsynaptic density. Science 290 (2000) 750-754
18. Liang D., Li X., and Clark J.D. Increased expression of ca2+/calmodulin-dependent protein kinase IIα during chronic morphine exposure. Neuroscience 13 (2004) 769-775
19. Limbird L.E. Receptors linked to inhibition of adenylate cyclase: additional signaling mechanisms. FASEB J. 2 (1988) 2686-2695
20. 2+/calmodulin-dependent Protein kinase II activity by acute and chronic morphine administration in rat hippocampus: differential regulation of α and β Isoforms. Mol. Pharmacol. 55 (1999) 557-563
21. Mao J., Price D.D., and Mayer D.J. Mechanisms of hyperalgesia and morphine tolerance: a current view of their possible interaction. Pain 62 (1995) 259-274
22. Mayer J., and Mao J. Mechanisms of opioid tolerance: current view of cellular mechanisms. Pain Forum 8 (1999) 14-18
23. Mayer D.J., Mao J., Holt J., and Price D. Cellular mechanisms of neuropathic pain, morphine tolerance, and their interactions. Proc. Nalt. Acad. Sci. USA 96 (1999) 7731-7736
24. Mayer J.M., Mao J., and Price D.D. The development of morphine tolerance and dependence is associated with translocation of protein kinase C. Pain 61 (1995) 365-374
25. Nestler E.J., and Aghajanian G.K. Molecular and cellular basis of addiction. Science 278 (1997) 58-63
26. Reddy S.V.R., and Yaksh T.L. Spinal noradrenergic terminal system mediates antinociception. Brain Res. 189 (1980) 391-401
27. Silva A.J., Paylor R., Wehner J.M., and Tonegawa S. Impaired spatial learning in a-calcium-calmodulin kinase II mutant mice. Science 257 (1992) 206-211
28. Trujillo K.A., and Akil H. Inhibition of opiate tolerance by non-competitive N-methyl-d-aspartate receptor antagonists. Brain Res. 633 (1994) 178-188
29. Vaccarino A.L., and Coutret J.r. Relationship between hypothalamic-pituitary-adrenal activity and blockade of tolerance to morphine analgesia by pain: a strain comparison. Pain 63 (1995) 385-389
30. Vaccarino A.L., Nores W.L., Soignier R.D., and Olson R.D. The role of corticosterone in the blockade to morphine analgesia by formalin- induced pain in the rat. Neurosci. Lett. 232 (1997) 139-142
31. Wang Z.J., Tang L., and Xin L. Reversal of morphine antinociceptive tolerance by acute spinal inhibition of Ca2+/calmodulin-dependent protein kinase II. Eur. J. Pharmacol. 465 (2003) 199-200
32. Williams J.T., Christie M.J., and Manzoni O. Cellular and synaptic adaptations mediating opioid dependence. Physiol. Rev. 81 (2001) 299-343
33. Xu T., Jiang W., Du D., Xu Y., Hu Q., and Shen Q. Role of spinal metabotropic glutamate receptor subtype 5 in the development of tolerance to morphine-induced antinociception in rat. Neurosci. Lett. 420 (2007) 155-159
34. Yaksh T.L., and Reddy S.V.R. Studies in the primate on the analgesic effects associated with intrathecal actions of opiates α-adrenergic agonists and baclofen. Anesthesiology 54 (1981) 451-467
35. Yaksh T.L., and Rudy T.A. Chronic catheterization of the spinal subarachnoid space. Physiol. Behav. 17 (1976) 1031-1036
36. Yamauchi T. Molecular constituents and phosphorylation-dependent regulation of the post-synaptic density. Mass Spectrom. Rev. 21 (2002) 266-286
37. Yamauchi T. Neuronal Ca2+/calmodulin-dependent protein kinase II discovery, progress in a quarter of a century, and perspective: implication for learning and memory. Biol. Pharm. Bull. 28 (2005) 1342-1354