Dexamethasone mimics the inhibitory effect of chronic pain on the development of tolerance to morphine analgesia and compensates for morphine induced changes in G proteins gene expression

Brain Research

Volumn 1104, Issue 1, 2006, Pages 73-79

  Javan, Mohammad ^a,b   Kazemi, Bahram ^b   Ahmadiani, Abolhassan ^b   Motamedi, Fereshteh ^b  

^a TARBIAT MODARES UNIVERSITY   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Dexamethasone; G proteins; Gene expression; Morphine tolerance; Rat

Indexed keywords

BETA ACTIN; DEXAMETHASONE; GLUCOCORTICOID; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; MORPHINE; PROTEIN SUBUNIT;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC PAIN; CONTROLLED STUDY; GENE EXPRESSION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LUMBAR SPINE; MALE; MORPHINE TOLERANCE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; TAIL FLICK TEST;

ANALGESICS, OPIOID; ANALYSIS OF VARIANCE; ANIMALS; ANTI-INFLAMMATORY AGENTS; BEHAVIOR, ANIMAL; DEXAMETHASONE; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; DRUG TOLERANCE; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; MALE; MORPHINE; PAIN; PAIN MEASUREMENT; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS;

RATTUS NORVEGICUS;

EID: 33746655714     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.05.088     Document Type: Article

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