Involvement of UDP-glucuronosyltransferase activity in irinotecan-induced delayed-onset diarrhea in rats

Cancer Chemotherapy and Pharmacology

Volumn 61, Issue 4, 2008, Pages 595-605

  Onoue, Masaharu ^a   Kurita, Akinobu ^a   Kado, Shoichi ^a   Matsumoto, Tsuneo ^a   Kaneda, Norimasa ^a   Uchida, Kazumi ^a   Kato, Ikuo ^a   Yokokura, Teruo ^a  

^a YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

Author keywords

CPT 11; Diarrhea; Gunn rat; Irinotecan hydrochloride; UDP glucuronosyltransferase

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; 7 ETHYL 10 HYDROXYCAMPTOTHECIN GLUCURONIDE; GLUCURONOSYLTRANSFERASE; IRINOTECAN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BILE SECRETION; CANCER CHEMOTHERAPY; CECUM; CONTROLLED STUDY; DELAYED ONSET DIARRHEA; DIARRHEA; DRUG HALF LIFE; DRUG TISSUE LEVEL; ENZYME ACTIVITY; GUNN RAT; INTESTINE EPITHELIUM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMALL INTESTINE;

ALGORITHMS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AREA UNDER CURVE; BILIRUBIN; CAMPTOTHECIN; CRIGLER-NAJJAR SYNDROME; DIARRHEA; GLUCURONOSYLTRANSFERASE; HYPERBILIRUBINEMIA; INTESTINES; RATS; RATS, GUNN; RATS, WISTAR;

EID: 38049042814     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-007-0512-x     Document Type: Article

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