-
1
-
-
0022485138
-
A phase II study of combined 5-fluorouracil, doxorubicin and cisplatin in the treatment of advanced upper gastrointestinal adenocarcinoma
-
Moertel CG, Rubin J, O'Connell MJ, et al: A phase II study of combined 5-fluorouracil, doxorubicin and cisplatin in the treatment of advanced upper gastrointestinal adenocarcinoma. J Clin Oncol 4:1053-1057, 1986
-
(1986)
J Clin Oncol
, vol.4
, pp. 1053-1057
-
-
Moertel, C.G.1
Rubin, J.2
O'Connell, M.J.3
-
2
-
-
0022624346
-
Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid
-
Machover D, Goldschmidt E, Chollet P, et al: Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid. J Clin Oncol 4:685-696, 1986
-
(1986)
J Clin Oncol
, vol.4
, pp. 685-696
-
-
Machover, D.1
Goldschmidt, E.2
Chollet, P.3
-
3
-
-
0024454042
-
Phase II with the combination of etoposide, doxorubicin, and cisplatin in advanced measurable gastric cancer
-
Preusser P, Wilke H, Achterrath W, et al: Phase II with the combination of etoposide, doxorubicin, and cisplatin in advanced measurable gastric cancer. J Clin Oncol 7:1310-1317, 1987
-
(1987)
J Clin Oncol
, vol.7
, pp. 1310-1317
-
-
Preusser, P.1
Wilke, H.2
Achterrath, W.3
-
4
-
-
0024447158
-
Preoperative chemotherapy in locally advanced and nonresectable gastric cancer: A phase II study with etoposide, doxorubicin and cisplatin
-
Wilke H, Preusser P, Fink U, et al: Preoperative chemotherapy in locally advanced and nonresectable gastric cancer: A phase II study with etoposide, doxorubicin and cisplatin. J Clin Oncol 7:1318-1326, 1989
-
(1989)
J Clin Oncol
, vol.7
, pp. 1318-1326
-
-
Wilke, H.1
Preusser, P.2
Fink, U.3
-
5
-
-
0026043230
-
New developments in the treatment of gastric carcinoma
-
Wilke H, Preusser P, Fink U, et al: New developments in the treatment of gastric carcinoma. Cancer Treat Res 55:363-373, 1991
-
(1991)
Cancer Treat Res
, vol.55
, pp. 363-373
-
-
Wilke, H.1
Preusser, P.2
Fink, U.3
-
6
-
-
0025762832
-
Sequential high-dose methotrexate and fluorouracil combined with doxorubicin: A step ahead in the treatment of gastric cancer: a trial of the EORTC
-
Wils JA, Klein HO, Wagener DJT, et al: Sequential high-dose methotrexate and fluorouracil combined with doxorubicin: A step ahead in the treatment of gastric cancer: A trial of the EORTC. J Clin Oncol 9:827-831, 1991
-
(1991)
J Clin Oncol
, vol.9
, pp. 827-831
-
-
Wils, J.A.1
Klein, H.O.2
Wagener, D.J.T.3
-
7
-
-
0026548710
-
FAMTX versus etoposide, doxorubicin, and cisplatin: A random assignment trial in gastric cancer
-
Kelsen D, Atiq OT, Saltz L, et al: FAMTX versus etoposide, doxorubicin, and cisplatin: A random assignment trial in gastric cancer. J Clin Oncol 10:541-548, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 541-548
-
-
Kelsen, D.1
Atiq, O.T.2
Saltz, L.3
-
8
-
-
0027198871
-
A phase III randomized study of 5-fluorouracil and cisplatin versus 5-fluorouracil, doxorubicin, and mitomycin C versus 5-fluorouracil alone in the treatment of advanced gastric cancer
-
Kim NK, Park YS, Heo DS, et al: A phase III randomized study of 5-fluorouracil and cisplatin versus 5-fluorouracil, doxorubicin, and mitomycin C versus 5-fluorouracil alone in the treatment of advanced gastric cancer. Cancer 71:3813-3918, 1993
-
(1993)
Cancer
, vol.71
, pp. 3813-3918
-
-
Kim, N.K.1
Park, Y.S.2
Heo, D.S.3
-
9
-
-
0028569654
-
Phase II study of protracted infusional 5-fluorouracil combined with cisplatinum for advanced gastric cancer: Report from the Japan Clinical Oncology Group (JCOG)
-
Ohtsu A, Shimada Y, Yoshida S, et al: Phase II study of protracted infusional 5-fluorouracil combined with cisplatinum for advanced gastric cancer: Report from the Japan Clinical Oncology Group (JCOG). Eur J Cancer 30A:2091-2093, 1994
-
(1994)
Eur J Cancer
, vol.30 A
, pp. 2091-2093
-
-
Ohtsu, A.1
Shimada, Y.2
Yoshida, S.3
-
10
-
-
0025792028
-
Combination chemotherapy with cisplatin and 5-fluorouracil 5-day infusion in the therapy of advanced gastric cancer: A phase II trial
-
Lacave AJ, Baron FJ, Anton LM, et al: Combination chemotherapy with cisplatin and 5-fluorouracil 5-day infusion in the therapy of advanced gastric cancer: A phase II trial. Ann Oncol 2:751-754, 1991
-
(1991)
Ann Oncol
, vol.2
, pp. 751-754
-
-
Lacave, A.J.1
Baron, F.J.2
Anton, L.M.3
-
11
-
-
7144248725
-
Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata
-
Wall ME, Wani MC, Cook CE, et al: Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata. J Am Chem Soc 88:3888-3890, 1966
-
(1966)
J Am Chem Soc
, vol.88
, pp. 3888-3890
-
-
Wall, M.E.1
Wani, M.C.2
Cook, C.E.3
-
12
-
-
0015291595
-
Phase II study of camptothecin (NSC-100880) in the treatment of advanced gastrointestinal cancer
-
Moertel CG, Schutt AJ, Reitemeier RJ, et al: Phase II study of camptothecin (NSC-100880) in the treatment of advanced gastrointestinal cancer. Cancer Chemother Rep 56:95-101, 1972
-
(1972)
Cancer Chemother Rep
, vol.56
, pp. 95-101
-
-
Moertel, C.G.1
Schutt, A.J.2
Reitemeier, R.J.3
-
13
-
-
0014895176
-
Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC-100880)
-
Gottlieb JA, Guarino AM, Call JB, et al: Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC-100880). Cancer Chemother Rep 54:461-470, 1970
-
(1970)
Cancer Chemother Rep
, vol.54
, pp. 461-470
-
-
Gottlieb, J.A.1
Guarino, A.M.2
Call, J.B.3
-
14
-
-
0023552964
-
Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin, a novel water-soluble derivative of camptothecin, against murine tumors
-
Kunimoto T, Nitta K, Tanaka T, et al: Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin, a novel water-soluble derivative of camptothecin, against murine tumors. Cancer Res 47:5944-5947, 1987
-
(1987)
Cancer Res
, vol.47
, pp. 5944-5947
-
-
Kunimoto, T.1
Nitta, K.2
Tanaka, T.3
-
15
-
-
0023395222
-
Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I
-
Andoh T, Ishii K, Suzuki Y, et al: Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I. Proc Natl Acad Sci USA 84:5565-5569, 1987
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 5565-5569
-
-
Andoh, T.1
Ishii, K.2
Suzuki, Y.3
-
16
-
-
0024356003
-
DNA topoisomerase I mediated DNA cleavage and cytotoxicity of camptothecin analogues
-
Hsiang YH, Liu LF, Wall ME, et al: DNA topoisomerase I mediated DNA cleavage and cytotoxicity of camptothecin analogues. Cancer Res 49:4835-4839, 1989
-
(1989)
Cancer Res
, vol.49
, pp. 4835-4839
-
-
Hsiang, Y.H.1
Liu, L.F.2
Wall, M.E.3
-
17
-
-
0023904035
-
Inhibition of spontaneous and experimental metastasis by a new derivative of camptothecin, CPT-11, in mice
-
Matsuzaki T, Yokokura T, Mutai M, et al: Inhibition of spontaneous and experimental metastasis by a new derivative of camptothecin, CPT-11, in mice. Cancer Chemother Pharmacol 21:308-312, 1988
-
(1988)
Cancer Chemother Pharmacol
, vol.21
, pp. 308-312
-
-
Matsuzaki, T.1
Yokokura, T.2
Mutai, M.3
-
18
-
-
0023864510
-
Antitumor effect of CPT-11, a new derivative of camptothecin, against pleiotropic drug-resistant tumor in vitro and vivo
-
Tsuruo T, Matsuzaki T, Matsushita M, et al: Antitumor effect of CPT-11, a new derivative of camptothecin, against pleiotropic drug-resistant tumor in vitro and vivo. Cancer Chemother Pharmacol 21:71-74, 1988
-
(1988)
Cancer Chemother Pharmacol
, vol.21
, pp. 71-74
-
-
Tsuruo, T.1
Matsuzaki, T.2
Matsushita, M.3
-
19
-
-
0026339352
-
Camptothecin overcomes MDR1-mediated resistance in human KB carcinoma cells
-
Chen AY, Yu C, Potmesil M, et al: Camptothecin overcomes MDR1-mediated resistance in human KB carcinoma cells. Cancer Res 51:6039-6044, 1991
-
(1991)
Cancer Res
, vol.51
, pp. 6039-6044
-
-
Chen, A.Y.1
Yu, C.2
Potmesil, M.3
-
20
-
-
0025129894
-
An early phase II study of CPT-11, a new derivative of camptothecin, for the treatment of leukemia and lymphoma
-
Ohno R, Okada K, Masaoka T, et al: An early phase II study of CPT-11, a new derivative of camptothecin, for the treatment of leukemia and lymphoma. J Clin Oncol 8:1907-1912, 1990
-
(1990)
J Clin Oncol
, vol.8
, pp. 1907-1912
-
-
Ohno, R.1
Okada, K.2
Masaoka, T.3
-
21
-
-
0026531753
-
A phase II study of CPT-11, a new derivative of camptothecin, for previously untreated non-small-cell lung cancer
-
Fukuoka M, Niitani H, Suzuki A, et al: A phase II study of CPT-11, a new derivative of camptothecin, for previously untreated non-small-cell lung cancer. J Clin Oncol 10:16-20, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 16-20
-
-
Fukuoka, M.1
Niitani, H.2
Suzuki, A.3
-
22
-
-
0026680292
-
CPT-11: A new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer
-
Masuda N, Fukuoka M, Kusunoki Y, et al: CPT-11: A new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer. J Clin Oncol 10:1225-1229, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 1225-1229
-
-
Masuda, N.1
Fukuoka, M.2
Kusunoki, Y.3
-
23
-
-
0011847828
-
Late phase II study of CPT-11, new camptothecin derivative, in cervical and ovarian carcinoma
-
abstr 0936
-
Noda K, Takeuchi S, Yakushiji M, et al: Late phase II study of CPT-11, new camptothecin derivative, in cervical and ovarian carcinoma. Proceedings of the 13th World Congress of Gynecology and Obstetrics (FIGO) 13:279, 1991 (abstr 0936)
-
(1991)
Proceedings of the 13th World Congress of Gynecology and Obstetrics (FIGO)
, vol.13
, pp. 279
-
-
Noda, K.1
Takeuchi, S.2
Yakushiji, M.3
-
24
-
-
0000177763
-
Late phase II study of CPT-11, topoisomerase I inhibitor, in advanced cervical carcinoma
-
abstr 708
-
Takeuchi S, Noda K, Yakushiji M, et al: Late phase II study of CPT-11, topoisomerase I inhibitor, in advanced cervical carcinoma. Proc Am Soc Clin Oncol 11:224, 1992 (abstr 708)
-
(1992)
Proc Am Soc Clin Oncol
, vol.11
, pp. 224
-
-
Takeuchi, S.1
Noda, K.2
Yakushiji, M.3
-
25
-
-
0027194943
-
Phase II study of CPT-11, new camptothecin derivative, in metastatic colorectal cancer
-
Shimada Y, Yoshino M, Wakui A, et al: Phase II study of CPT-11, new camptothecin derivative, in metastatic colorectal cancer. J Clin Oncol 11:909-913, 1993
-
(1993)
J Clin Oncol
, vol.11
, pp. 909-913
-
-
Shimada, Y.1
Yoshino, M.2
Wakui, A.3
-
26
-
-
0001657427
-
A late phase II study of irinotecan (CPT-11) in patients with advanced gastric cancers
-
abstr 584
-
Kambe M, Wakui A, Nakao I, et al: A late phase II study of irinotecan (CPT-11) in patients with advanced gastric cancers. Proc Am Soc Clin Oncol 12:198, 1993 (abstr 584)
-
(1993)
Proc Am Soc Clin Oncol
, vol.12
, pp. 198
-
-
Kambe, M.1
Wakui, A.2
Nakao, I.3
-
27
-
-
0000198398
-
Synergistic effects of CPT-11 and cisplatin or etoposide on human lung cancer cell lines demonstrated by computer analysis
-
abstr 459
-
Itoh K, Takada M, Kudo S, et al: Synergistic effects of CPT-11 and cisplatin or etoposide on human lung cancer cell lines demonstrated by computer analysis. Lung Cancer 7:124, 1991 (abstr 459)
-
(1991)
Lung Cancer
, vol.7
, pp. 124
-
-
Itoh, K.1
Takada, M.2
Kudo, S.3
-
28
-
-
0027479925
-
Enhanced antitumor efficacy of a combination of CPT-11, a new derivative of camptothecin, and cisplatin against human lung tumor xenografts
-
Kudoh S, Takada M, Masuda N, et al: Enhanced antitumor efficacy of a combination of CPT-11, a new derivative of camptothecin, and cisplatin against human lung tumor xenografts. Jpn J Cancer Res 84:203-207, 1993
-
(1993)
Jpn J Cancer Res
, vol.84
, pp. 203-207
-
-
Kudoh, S.1
Takada, M.2
Masuda, N.3
-
29
-
-
0027965156
-
Synergistic enhancement of cisplatin cytotoxicity by SN-38, an active metabolite of CPT-11, for cisplatin-resistant HeLa cells
-
Minagawa Y, Kigawa J, Ishikawa H, et al: Synergistic enhancement of cisplatin cytotoxicity by SN-38, an active metabolite of CPT-11, for cisplatin-resistant HeLa cells. Jpn J Cancer Res 85:966-971, 1994
-
(1994)
Jpn J Cancer Res
, vol.85
, pp. 966-971
-
-
Minagawa, Y.1
Kigawa, J.2
Ishikawa, H.3
-
30
-
-
0343854892
-
Combination effects of CPT-11 and CDDP against human cell line: In vitro and in vivo examinations
-
abstr 2241
-
Kondo H, Shimada Y, Shirao K, et al: Combination effects of CPT-11 and CDDP against human cell line: In vitro and in vivo examinations. Jpn J Cancer Res 85:616, 1994 (abstr 2241)
-
(1994)
Jpn J Cancer Res
, vol.85
, pp. 616
-
-
Kondo, H.1
Shimada, Y.2
Shirao, K.3
-
31
-
-
0029047211
-
Inhibition of cisdiamminedichloroplatinum (II)-induced DNA interstrand cross-link removal by 7-ethyl-10-hydroxy-camptothecin in HST-1 human squamous-carcinoma cells
-
Masumoto N, Nakano S, Esaki T, et al: Inhibition of cisdiamminedichloroplatinum (II)-induced DNA interstrand cross-link removal by 7-ethyl-10-hydroxy-camptothecin in HST-1 human squamous-carcinoma cells. Int J Cancer 62:70-75, 1995
-
(1995)
Int J Cancer
, vol.62
, pp. 70-75
-
-
Masumoto, N.1
Nakano, S.2
Esaki, T.3
-
32
-
-
0027082880
-
CPT-11 in combination with cisplatin for advanced non-small-cell lung cancer
-
Masuda N, Fukuoka M, Takada M, et al: CPT-11 in combination with cisplatin for advanced non-small-cell lung cancer. J Clin Oncol 10:1775-1780, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 1775-1780
-
-
Masuda, N.1
Fukuoka, M.2
Takada, M.3
-
33
-
-
0027372606
-
Phase I and pharmacologic study of irinotecan in combination with cisplatin for advanced lung cancer
-
Masuda N, Fukuoka M, Kudoh S, et al: Phase I and pharmacologic study of irinotecan in combination with cisplatin for advanced lung cancer. Br J Cancer 68:777-782, 1993
-
(1993)
Br J Cancer
, vol.68
, pp. 777-782
-
-
Masuda, N.1
Fukuoka, M.2
Kudoh, S.3
-
34
-
-
0001547261
-
A late phase II study of irinotecan (CPT-11) in advanced pancreas cancer
-
abstr 633
-
Sakata Y, Wakui A, Nakao I, et al: A late phase II study of irinotecan (CPT-11) in advanced pancreas cancer. Proc Am Soc Clin Oncol 12:211, 1993 (abstr 633)
-
(1993)
Proc Am Soc Clin Oncol
, vol.12
, pp. 211
-
-
Sakata, Y.1
Wakui, A.2
Nakao, I.3
-
35
-
-
0003486931
-
-
WHO Offset Publication No. 48. Geneva, Switzerland, World Health Organization
-
World Health Organization: WHO Handbook for Reporting Results of Cancer Treatment. WHO Offset Publication No. 48. Geneva, Switzerland, World Health Organization, 1979
-
(1979)
WHO Handbook for Reporting Results of Cancer Treatment
-
-
-
37
-
-
0020396015
-
Toxicity and response criteria of the Eastern Cooperative Oncology Group
-
Oken MM, Creech RH, Tormey DC, et al: Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 5:649-655, 1982
-
(1982)
Am J Clin Oncol
, vol.5
, pp. 649-655
-
-
Oken, M.M.1
Creech, R.H.2
Tormey, D.C.3
-
38
-
-
0025851286
-
Phase I study of weekly intravenous infusions of CPT-11, a new derivative of camptothecin, in the treatment of advanced non-small-cell lung cancer
-
Negoro S, Fukuoka M, Masuda N, et al: Phase I study of weekly intravenous infusions of CPT-11, a new derivative of camptothecin, in the treatment of advanced non-small-cell lung cancer. J Natl Cancer Inst 83:1164-1168, 1991
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 1164-1168
-
-
Negoro, S.1
Fukuoka, M.2
Masuda, N.3
-
39
-
-
0027140524
-
Phase I and pharmacokinetic trial of weekly CPT-11
-
Rothenberg ML, Kuhn JB, Bums HA III, et al: Phase I and pharmacokinetic trial of weekly CPT-11. J Clin Oncol 11:2194-2204, 1993
-
(1993)
J Clin Oncol
, vol.11
, pp. 2194-2204
-
-
Rothenberg, M.L.1
Kuhn, J.B.2
Bums H.A. III3
-
40
-
-
0027933519
-
Phase I and pharmacokinetic study of the camptothecin derivative irinotecan administered on a weekly schedule in cancer patients
-
de Forni M, Bugat R, Chabot GG, et al: Phase I and pharmacokinetic study of the camptothecin derivative irinotecan administered on a weekly schedule in cancer patients. Cancer Res 54:4347-4354, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 4347-4354
-
-
De Forni, M.1
Bugat, R.2
Chabot, G.G.3
-
41
-
-
0028158012
-
Phase I and pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks
-
Rowinsky EK, Grochow LB, Ettinger DS, et al: Phase I and pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks. Cancer Res 54:427-436, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 427-436
-
-
Rowinsky, E.K.1
Grochow, L.B.2
Ettinger, D.S.3
-
42
-
-
0028854897
-
Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients
-
Abigerges D, Chabot G, Armand J, et al: Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients. J Clin Oncol 13:210-221, 1995
-
(1995)
J Clin Oncol
, vol.13
, pp. 210-221
-
-
Abigerges, D.1
Chabot, G.2
Armand, J.3
-
43
-
-
0028840093
-
Phase I and pharmacologic study of irinotecan (CPT-11) administered daily for three consecutive days every three weeks in patients with advanced solid tumors
-
Catimel G, Chabot GG, Guastalla JP. et al: Phase I and pharmacologic study of irinotecan (CPT-11) administered daily for three consecutive days every three weeks in patients with advanced solid tumors. Ann Oncol 6:133-140, 1995
-
(1995)
Ann Oncol
, vol.6
, pp. 133-140
-
-
Catimel, G.1
Chabot, G.G.2
Guastalla, J.P.3
-
44
-
-
0026631164
-
Phase I study and pharmacokinetics of CPT-11 with 5-day continuous infusion
-
Ohe Y, Sasaki Y, Shinkai T, et al: Phase I study and pharmacokinetics of CPT-11 with 5-day continuous infusion. J Natl Cancer Inst 84:972-974, 1992
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 972-974
-
-
Ohe, Y.1
Sasaki, Y.2
Shinkai, T.3
-
45
-
-
0028853410
-
Population pharmacokinetics and pharmacodynamics of irinotecan (CPT-11) and active metabolite SN-38 during phase I trials
-
Chabot GG, Abigerges D, Catimel G, et al: Population pharmacokinetics and pharmacodynamics of irinotecan (CPT-11) and active metabolite SN-38 during phase I trials. Ann Oncol 6:141-151, 1995
-
(1995)
Ann Oncol
, vol.6
, pp. 141-151
-
-
Chabot, G.G.1
Abigerges, D.2
Catimel, G.3
|