Comparison of the effects of two long-acting beta2-agonists on cytokine secretion by human airway epithelial cells

Journal of Microbiology, Immunology and Infection

Volumn 40, Issue 5, 2007, Pages 388-394

  Chiu, Jou Chia ^a   Hsu, Jeng Yuan ^a   Fu, Lin Shien ^a   Chu, Jao Jia ^a   Chi, N Shiang ^a  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Adrenergic beta agonists; Formoterol; Granulocyte macrophage colony stimulating factor; Interleukin 8; Salmeterol; Vascular endothelial growth factor A

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; FORMOTEROL; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 8; LONG ACTING DRUG; SALMETEROL; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRONCHUS MUCOSA; CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; DRUG SENSITIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; HUMAN; HUMAN CELL;

ADRENERGIC BETA-AGONISTS; ALBUTEROL; ANTI-INFLAMMATORY AGENTS; CELL LINE; CYTOKINES; EPITHELIAL CELLS; ETHANOLAMINES; HUMANS; RECEPTORS, ADRENERGIC, BETA-2; RESPIRATORY MUCOSA;

EID: 38049013833     PISSN: 16841182     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Woolcock A, Lundback B, Ringdal N, Jacques LA. Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids. Am J Respir Crit Care Med. 1996;153:1481-8.
2. Pauwels RA, Löfdahl CG, Postma DS, Tattersfield AE, O'Byrne P, Barnes PJ, et al. Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N Engl J Med. 1997;337:1405-11.
3. Hancox RJ, Cowan JO, Flannery EM, Herbison GP, McLachlan CR, Wong CS, et al. Randomised trial of an inhaled beta2 agonist, inhaled corticosteroid and their combination in the treatment of asthma. Thorax. 1999;54:482-7.
4. Seldon PM, Stevens DA, Adcock IM, O'Connor BJ, Barnes PJ, Giembycz MA. Albuterol does not antagonize the inhibitory effect of dexamethasone on monocyte cytokine release. Am J Respir Crit Care Med. 1998;157:803-9.
5. Oddera S, Silvestri M, Testi R, Rossi GA. Salmeterol enhances the inhibitory activity of dexamethasone on allergen-induced blood mononuclear cell activation. Respiration. 1998;65:199-204.
6. Stelmach I, Gorski P, Jerzynska J, Stelmach W, Majak P, Kuna P. A randomized, double-blind trial of the effect of treatment with formoterol on clinical and inflammatory parameters of asthma in children. Ann Allergy Asthma Immunol. 2002;89:67-73.
7. Jeffery PK, Venge P, Gizycki MJ, Egerod I, Dahl R, Faurschou P. Effects of salmeterol on mucosal inflammation in asthma: a placebo-controlled study. Eur Respir J. 2002;20:1378-85.
8. Pinto Pereira LM, Clement Y, Rouse J, Matthew J, Asgarali Z, Ramoutar D. Salmeterol decreases eosinophilic cationic protein and rescue medication in patients inhaling beclomethasone dipropionate: preliminary study in mild and moderate asthma in Trinidad, West Indies. Int J Clin Pharmacol Res. 2003;23:69-74.
9. Reid DW, Ward C, Wang N, Zheng L, Bish R, Orsida B, et al. Possible anti-inflammatory effect of salmeterol against interleukin-8 and neutrophil activation in asthma in vivo. Eur Respir J. 2003;21:994-9.
10. Abraham G, Kneuer C, Ehrhardt C, Honscha W, Ungemach FR. Expression of functional beta2-adrenergic receptors in the lung epithelial cell lines 16HBE14o(-), Calu-3 and A549. Biochim Biophys Acta. 2004;1691:169-79.
11. Johnson M. Effects of beta2-agonists on resident and infiltrating inflammatory cells. J Allergy Clin Immunol. 2002;110(Suppl 6):S282-90.
12. Kleine-Tebbe J, Frank G, Josties C, Kunkel G. Influence of salmeterol, a long-acting beta 2-adrenoceptor agonist, on IgE-mediated histamine release from human basophils. J Investig Allergol Clin Immunol. 1994;4:12-7.
13. Chong LK, Cooper E, Vardey CJ, Peachell PT. Salmeterol inhibition of mediator release from human lung mast cells by beta-adrenoceptor-dependent and independent mechanisms. Br J Pharmacol. 1998;123:1009-15.
14. McDonald DM. Angiogenesis and remodeling of airway vasculature in chronic inflammation. Am J Respir Crit Care Med. 2001;164:S39-45.
15. Norzila MZ, Fakes K, Henry RL, Simpson J, Gibson PG. Interleukin-8 secretion and neutrophil recruitment accompanies induced sputum eosinophil activation in children with acute asthma. Am J Respir Crit Care Med. 2000;161:769-74.
16. Ackerman V, Marini M, Vittori E, Bellini A, Vassali G, Mattoli S. Detection of cytokines and their cell sources in bronchial biopsy specimens from asthmatic patients. Relationship to atopic status, symptoms, and level of airway hyperresponsiveness. Chest. 1994;105:687-96.
17. Lieber M, Smith B, Szakal A, Nelson-Rees W, Todaro G. A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells. Int J Cancer. 1976;17:62-70.
18. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983;65:55-63.
19. Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention, NHLBI/WHO Workshop Report, Updated 2003. London: Global Initiative for Asthma. Available from: https.ginasthma.com/wr_clean.pdf
20. Shrewsbury S, Pyke S, Britton M. Meta-analysis of increased dose of inhaled steroid or addition of salmeterol in symptomatic asthma (MIASMA). BMJ. 2000;320:1368-73.
21. Borger P, Hoekstra Y, Esselink MT, Postma DS, Zaagsma J, Vellenga E, et al. Beta-adrenoceptor-mediated inhibition of IFN-gamma, IL-3, and GM-CSF mRNA accumulation in activated human T lymphocytes is solely mediated by the beta2- adrenoceptor subtype. Am J Respir Cell Mol Biol. 1998;19:400-7.
22. Anderson GP. Formoterol: pharmacology, molecular basis of agonism, and mechanism of long duration of a highly potent and selective beta 2-adrenoceptor agonist bronchodilator. Life Sci. 1993;52:2145-60.
23. Eickelberg O, Roth M, Lörx R, Bruce V, Rüdiger J, Johnson M, et al. Ligand-independent activation of the glucocorticoid receptor by beta2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells. J Biol Chem. 1999;274:1005-10.
24. Cadepond F, Ulmann A, Baulieu EE. RU486 (mifepristone): mechanisms of action and clinical uses. Annu Rev Med. 1997;48:129-56.
25. Baouz S, Giron-Michel J, Azzarone B, Giuliani M, Cagnoni F, Olsson S, et al. Lung myofibroblasts as targets of salmeterol and fluticasone propionate: inhibition of alpha-SMA and NF-kappaB. Int Immunol. 2005;17:1473-81.
26. Korn SH, Jerre A, Brattsand R. Effects of formoterol and budesonide on GM-CSF and IL-8 secretion by triggered human bronchial epithelial cells. Eur Respir J. 2001;17:1070-7.
27. Ameredes BT, Calhoun WJ. Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle. J Allergy Clin Immunol. 2005;116:65-72.
28. Chorley BN, Li Y, Fang S, Park JA, Adler KB. (R)-albuterol elicits antiinflammatory effects in human airway epithelial cells via iNOS. Am J Respir Cell Mol Biol. 2006;34:119-27.