Albuterol does not antagonize the inhibitory effect of dexamethasone on monocyte cytokine release

American Journal of Respiratory and Critical Care Medicine

Volumn 157, Issue 3 PART I, 1998, Pages 803-809

  Seldon, Paul M ^b   Stevens, David A ^b   Adcock, Ian M ^b   O'Connor, Brian J ^b   Barnes, Peter J ^b   Giembycz, Mark A ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; SALBUTAMOL; TUMOR NECROSIS FACTOR;

ARTICLE; ASTHMA; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; HUMAN; HUMAN CELL; MORTALITY; PRIORITY JOURNAL;

ADRENERGIC BETA-AGONISTS; ALBUTEROL; ANTI-INFLAMMATORY AGENTS; ASTHMA; BRONCHODILATOR AGENTS; CELLS, CULTURED; CYTOKINES; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOCORTICOIDS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INFLAMMATION MEDIATORS; LEAST-SQUARES ANALYSIS; LIPOPOLYSACCHARIDES; MONOCYTES; PROMOTER REGIONS (GENETICS); RECEPTORS, GLUCOCORTICOID; REGRESSION ANALYSIS; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031945936     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.157.3.9707116     Document Type: Article

References (33)

1. Corrigan, C. J., and A. B. Kay. 1992. T cells and eosinophils in the pathogenesis of asthma. Immunol. Today 13:501-507.
2. Barnes, P. J. 1995. Inhaled glucocorticoids for asthma. N. Engl J. Med. 332:868-875.
3. Barnes, P. J., and I. M. Adcock. 1993. Anti-inflammatory actions of steroids: molecular mechanisms. Trends Pharmacol. Sci. 14:436-441.
4. Evans, R., D. I. Mullally, R. W. Wilson, P. J. Gergen, H. M. Rosenberg, J. S. Grauman, F. M. Chevarley, and M. Feinleib. 1987. National trends in the morbidity and mortality of asthma in the US: prevalence, hospitalization and death from asthma over two decades. Chest 91 (Suppl. 6):65S-74S.
5. Burr, M. L. 1987. Is asthma increasing? J. Epidemiol. Commun. Health 41:185-189.
6. Burney, P. G. 1992. Asthma epidemiology. Br. Med. Bull. 48:10-22.
7. 2-agonist controversy: observations, explanations and relationship to asthma epidemiology. Drug Safety 11:259-283.
8. Peters, M. J., I. A. Adcock, C. A. Brown, and P. J. Barnes. 1995. β-Adrenoceptor agonists interfere with glucocorticoid receptor DNA binding in rat lung. Eur. J. Pharmacol. (Mol. Pharmacol. Section: EJPMOL) 289:275-281.
9. Peters, M. J., I. A. Adcock, C. A. Brown, and P. J. Barnes. 1993. β-Agonist inhibition of steroid receptor DNA-binding activity in human lung (abstract). Am. Rev. Respir. Dis. 147:A772.
10. Stevens, D. A., P. J. Barnes, and I. M. Adcock. 1993. β-Agonists inhibit DNA binding of glucocorticoid receptors in human pulmonary and bronchial epithelial cells (abstract). Am. Rev. Respir. Dis. 151:A195.
11. Imai, E., J. N. Miner, J. A. Mitchell, K. R. Yamamoto, and D. K. Granner. 1993. Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxy kinase gene to glucocorticoids. J. Biol. Chem. 268:5353-5356.
12. Suissa, S., P. Ernst, J. F. Boivan, R. I. Horwitz, B. Habbick, D. Cock croft, L. Biais, M. McNutt, A. S. Buist, and W. O. Spitzer. 1994. A cohort analysis of excess mortality in asthma and the use of inhaled betaagonists. Am. Rev. Respir. Dis. 149:604-610.
13. Hagiwara, M., A. Alberts, P. Brindle, J. Meinkoth, J. Feramisco, T. Deng, M. Karin, and M. Shenolikar. 1992. Transcriptional attenuation following cAMP induction requires PP-1 mediated dephosphorylation of CREB. Cell 70:105-113.
14. Ponta, H., A. C. B. Cato, and P. Herrlich. 1992. Interference of pathway specific transcription factors. Biochim. Biophys. Acta 1129:255-261.
15. Wong, C. S., I. Wahedna, I. D. Pavord, and A. E. Tattersfield. 1994. Effect of regular terbutaline and budesonide on bronchial reactivity to allergen challenge. Am. J. Respir. Crit. Care Med. 150:1268-1273.
16. Arm, J. P., and T. H. Lee. 1992. The pathobiology of bronchial asthma. Adv. Immunol. 51:323-382.
17. Broide, D. H., M. Lotz, A. J. Cuomon, D. A. Coburn, E. C. Federman, and S. I. Wasserman. 1992. Cytokines in symptomatic asthma. J. Allergy Clin. Immunol. 89:958-967.
18. Gosset, P., A. Tsicopoulos, B. Wallaert, M. Joseph, A. Capron, and A. B. Tonnel. 1992. Tumor necrosis factor alpha and interleukin-6 production by human mononuclear phagocytes from allergic asthmatics after IgE-dependent stimulation. Am. Rev. Respir. Dis. 146:768-774.
19. Ohkawara, Y., K. Yamauchi, Y. Tanno, G. Tamura, H. Ohtani, H. Nagura, K. Ohkuda, and T. Takishima. 1992. Human lung mast cells and pulmonary macrophages produce tumor necrosis factor-alpha in sensitized lung tissue after IgE receptor triggering. Am. J. Respir. Cell Mol. Biol. 7:385-392.
20. Ying, S., D. S. Robinson, V. Varney, Q. Meng, A. Tsicopoulos, R. Moqbel, S. R. Durham, A. B. Kay, and Q. Hamid. 1991. TNF alpha mRNA expression in allergic inflammation. Clin. Exp. Allergy 21:745-750.
21. Gosset, P., A. Tsicopoulos, B. Wallaert, C. Vannimenus, M. Joseph, A. B. Tonnel, and A. Capron. 1991. Increased secretion of tumor necrosis factor alpha and interleukin-6 by alveolar macrophages consecutive to the development of the late asthmatic reaction. J. Allergy Clin. Immunol. 88:561-571.
22. Sousa, A. R., R. N. Poston, S. J. Lane, J. A. Narhosteen, and T. H. Lee. 1992. Detection of GM-CSF in asthmatic bronchial epithelium and decrease by inhaled corticosteroids. Am. J. Respir. Dis. 147:1557-1561.
23. Brown, P. A., G. K. Crompton, and A. P. Greening. 1991. Pro-inflamma tory cytokines in acute asthma. Lancet 338:590-593.
24. Nakamura, Y., T. Ozaki, T. Kamgi, K. Kawaji, K. Banno, S. Miki, K. Fujisawa, S. Yasuora, and T. Ogura. 1993. Increased granulocyte/macrophage colony-stimulating factor production by mononuclear cells from peripheral blood of patients with bronchial asthma. Am. Rev. Respir. Dis. 147:87-91.
25. Hallsworth, M. P., T. M. Litchfield, and T. H. Lee. 1992. Glucocorticosteroids inhibit granulocyte/macrophage colony-stimulating factor and interleukin-5 enhanced in vitro survival of human eosinophils. Immunology 75:382-385.
26. Silberstein, D. S., W. F. Owen, J. C. Gasson, J. F. Di Pierso, D. W. Golde, J. C. Bina, R. J. Soberman, K. F. Austen, and J. R. David. 1986. Enhancement of human eosinophil cytotoxicity and leukotriene synthesis by biosynthetic (recombinant) granulocyte/macrophage colony-stimulating factor. J. Immunol. 137:3290-3294.
27. Seldon, P. M., K. Meja, P. J. Barnes, and M. A. Giembycz. 1995. Suppression of lipopolysaccharide-induced tumor necrosis factor-α generation from human peripheral blood monocytes by inhibitors of phosphodiesterase 4: interaction with stimulants of adenylyl cyclase. Mol. Pharmacol 48:747-757.
28. Strauber, C., J. Altschmied, I. E. Akerblom, J. L. Marron, and P. L. Mellon. 1992. Mutual cross-interference between glucocorticoid receptor and CREB inhibits transactivation in placental cells. New Biologist 4: 527-540.
29. Pennie, W. D., G. L. Hager, and C. L. Smith. 1995. Nucleoprotein structure influences the response of the mouse mammary tumor virus promoter to activation of the cyclic AMP-signalling pathway. Mol. Cell Biol. 12:2125-2134.
30. Janknecht, R., and T. A. Hunter. 1997. A growing coactivator network. Nature 383:22-23.
31. Wolfe, A. P. 1997. Sinful repression. Nature 387:16-17.
32. Tomita, K., T. Tanigawa, H. Yajima, K. Fukutani, Y. Matsumoto, Y. Tanaka, and T. Sasaki. 1995. Identification and characterization of monocyte subpopulations from patients with bronchial asthma. J. Allergy Clin. Immunol. 96:230-238.
33. Gin, W., and A. B. Kay. 1985. The effect of corticosteroids on monocyte and neutrophil activation in bronchial asthma. J. Allergy Clin. Immunol 76:675-682.