Quantifying soluble HLA-G in supernatants of cultured embryos as a marker of implantation potential in an assisted reproduction program

Inmunologia

Volumn 26, Issue 3, 2007, Pages 127-134

  Marti S ^a   Ten, J ^b   Marcos, P ^a   Artacho, M J ^a   Galan F J ^c   Bernabeu, R ^a,b   Rubio Pedraza, Gonzalo ^a,d  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b Bernabeu Institute of Fertility and Gynecology   (Spain)

^c Centro de Genetica Humana   (Spain)

^d Campus de Sant Joan ^*  (Spain)

Author keywords

Embryo culture; ICSI; Pregnancy; sHLA G

Indexed keywords

HLA G ANTIGEN;

ARTICLE; CHORIOCARCINOMA; CONTROLLED STUDY; EMBRYO CULTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; FERTILIZATION IN VITRO; HUMAN; HUMAN CELL; IN VITRO STUDY; PREIMPLANTATION EMBRYO; REPRODUCTION; SUPERNATANT;

EID: 38049004312     PISSN: 02139626     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0213-9626(07)70082-3     Document Type: Article

References (35)

1. Ellis SA, Sargent IL, Redman CWG, McMichael AJ. Evidence for a novel HLA antigen found on human extravillous trophoblast and a choriocarcinoma cell-line. Immunology 1986; 59:595-601.
2. Fanchin R, Gallot V, Rouas-Freiss N, Frydman R, Carosella ED. Implication of HLA-G in human embryo implantation. Hum Immunol 2007; 68:259-263.
3. Ishitani A, Geraghty DE. Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class-I and class-II antigens. Proc Natl Acad Sci USA 1992; 89:3947-3951.
4. Kirszenbaum M, Moreau P, Gluckman E, Dausset J, Carosella E. An alternatively spliced form of HLA-G messenger-RNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes. Proc Natl Acad Sci USA 1994; 91:4209-4213.
5. Le Bouteiller P, Blaschitz A. The functionality of HLA-G is emerging. Immunol Rev 1999; 167:233-244.
6. The Anthony Nolan Trust (2007) http://www.anthonynolan.org.uk/HIG/ (9 July 2007).
7. Bainbridge DRJ, Ellis SA, Sargent IL. The short forms of HLA-G are unlikely to play a role in pregnancy because they are not expressed at the cell surface. J Reprod Immunol 2000; 47:1-16.
8. Mallet V, Proll J, Solier C, Aguerre-Girr M, DeRossi M, Loke YW, et al. The full length HLA-G1 and no other alternative form of HLA-G is expressed at the cell surface of transfected cells. Hum Immunol 2000; 61:212-224.
9. Ulbrecht M, Maier S, Hofmeister V, Falk CS, Brooks AG, McMaster MT, et al. Truncated HLA-G isoforms are retained in the endoplasmic reticulum and insufficiently provide HLA-E ligands. Hum Immunol 2004; 65:200-208.
10. Paul P, Cabestre FA, Ibrahim E, Lefebvre S, Khalil-Daher I, Vazeux G, et al. Identification of HLA-G7 as a new splice variant of the HLA-G mRNA and expression of soluble HLA-G5, -G6, and -G7 transcripts in human transfected cells. Hum Immunol 2000; 61:1138-1149.
11. Park GM, Lee S, Park B, Kim E, Shin J, Cho K, et al. Soluble HLA-G generated by proteolytic shedding inhibits NK-mediated cell lysis. Biochem Biophys Res Commun 2004; 313:606-611.
12. Jurisicova A, Casper RF, MacLusky NJ, Mills GB, Librach CL. HLA-G expression during preimplantation human embryo development. Proc Natl Acad Sci USA 1996; 93:161-165.
13. Menicucci A, Noci I, Fuzzi B, Criscuoli L, Scarselli G, Baricordi O, et al. Non-classic sHLA class I in human oocyte culture medium. Hum Immunol 1999; 60:1054-1057.
14. Van Montfoort APA, Dumoulin JCM, Rester ADM, Evers JLH. Early cleavage is a valuable addition to existing embryo selection parameters: a study using single embryo transfers. Hum Reprod 2004; 19:2103-2108.
15. Sher G, Keskintepe L, Fisch J, Acacio B, Ahlering P, Batzofin J, et al. Soluble human leukocyte antigen G expression in phase I culture media at 46 hours after fertilization predicts pregnancy and implantation from day 3 embryo transfer. Fertil Steril 2005; 83:1410-1413.
16. Noci I, Fuzzi B, Rizzo R, Melchiorri L, Criscuoli L, Dabizzi S, et al. Embryonic soluble HLA-G as a marker of developmental potential in embryos. Hum Reprod 2005; 20:138-146.
17. Yie S, Balakier H, Motamedi G, Librach CL. Secretion of human leukocyte antigen-G by human embryos is associated with a higher in vitro fertilization pregnancy rate. Fertil Steril 2005; 83:30-36.
18. Desai N, Filipovits J, Goldfarb J. Secretion of soluble HLA-G by day 3 human embryos associated with higher pregnancy and implantation rates: assay of culture media using a new ELISA kit. Reprod Biomed Online 2006; 13:272-277.
19. Rebmann V, Switala M, Eue I, Schwahn E, Merzenich M, Grosse-Wilde H. Rapid evaluation of soluble HLA-G levels in supernatants of in vitro fertilized embryos. Hum Immunol 2007; 68:251-258.
20. Menezo Y, Elder K, Viville S. Soluble HLA-G release by the human embryo: an interesting artefact? Reprod Biomed Online 2006; 13:763-764.
21. Sageshima N, Shobu T, Awai K, Hashimoto H, Yamashita M, Takeda N, et al. Soluble HLA-G is absent from human embryo cultures: A reassessment of sHLA-G detection methods. J Reprod Immunol 2007; In press.
22. Vansteirteghem AC, Nagy Z, Joris H, Jiaen L, Staessen C, Smitz J, et al. High fertilization and implantation rates after intracytoplasmic sperm injection. Hum Reprod 1993; 8:1061-1066.
23. Plikaytis BD, Carlone GM. Statistical considerations for vaccine immunogenicity trials Part 1: introduction and bioassay design and analysis. Vaccine 2005; 23:1596-1605.
24. Rubio G, Garcia-Garcia J, Galvez J, Lorenzo N, Lajarin F, Garcia-Penarrubia P. Determination of parameters that characterize effector-target conjugation of human NK and LAK cells by flow cytometry. J Immunol Methods 1997; 209:137-154.
25. Yao YQ, Barlow DH, Sargent IL. Differential expression of alternatively spliced transcripts of HLA-G in human preimplantation embryos and inner cell masses. J Immunol 2005; 175: 8379-8385.
26. Fuzzi B, Rizzo R, Criscuoli L, Noci I, Melchiorri L, Scarselli B, et al. HLA-G expression in early embryos is a fundamental prerequisite for the obtainment of pregnancy. Eur J Immunol 2002; 32:311-315.
27. van Lierop MJC, Wijnands F, Loke YW, Emmer PM, Lukassen HGM, Braat DDM, et al. Detection of HLA-G by a specific sandwich ELISA using monoclonal antibodies G233 and 56B. Molecular Hum Reprod 2002; 8:776-784.
28. Rebmann V, LeMaoult J, Rouas-Freiss N, Carosella ED, Grosse-Wilde H. Report of the Wet Workshop for Quantification of soluble HLA-G in Essen, 2004. Hum Immunol 2005; 66:853-863.
29. Juch H, Blaschitz A, Daxbock C, Rueckert C, Kofler K, Dohr G. A novel sandwich ELISA for alpha 1 domain based detection of soluble HLA-G heavy chains. J Immunol Methods 2005; 307:96-106.
30. Sargent I, Swales A, Ledee N, Kozma N, Tabiasco J, Le Bouteiller P. sHLA-G production by human IVF embryos: Can it be measured reliably? J Reprod Immunol 2007; In press.
31. Tesarik J, Kopecny V, Plachot M, Mandelbaum J, Dalage C, Flechon JE. Nucleologenesis in the human-embryo developing invitro - ultrastructural and autoradiographic analysis. Dev Biol 1986; 115:193-203.
32. Braude P, Bolton V, Moore S. Human-gene expression 1st occurs between the 4-cell and 8-cell stages of preimplantation development. Nature 1988; 332:459-461.
33. Rizzo R, Melchiom L, Stignani M, Baricordi OR. HLA-G expression is a fundamental prerequisite to pregnancy. Hum Immunol 2007; 68:244-250.
34. Roberts JM, Taylor CT, Melling GC, Kingsland CR, Johnson PM. Expression of the CD46 antigen, and absence of class-I MHC antigen, on the human oocyte and preimplantation blastocyst. Immunology 1992; 75:202-205.
35. Yie SM, Li LH, Li GM, Xiao R, Librach CL. Progesterone enhances HLA-G gene expression in JEG-3 choriocarcinoma cells and human cytotrophoblasts in vitro. Hum Reprod 2006; 21:46-51.