Early cleavage is a valuable addition to existing embryo selection parameters: A study using single embryo transfers

Human Reproduction

Volumn 19, Issue 9, 2004, Pages 2103-2108

  Van Montfoort, Aafke P A ^a   Dumoulin, John C M ^a   Kester, Arnold D M ^b   Evers, Johannes L H ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Blastocyst development; Early cleavage; Embryo quality; Pregnancy; Single embryo transfer

Indexed keywords

CHORIONIC GONADOTROPIN; NAFARELIN ACETATE; RECOMBINANT FOLLITROPIN; TRIPTORELIN;

ARTICLE; ARTIFICIAL INSEMINATION; BLASTOCYST; CELL COUNT; CELL DIVISION; CELL STRUCTURE; DEVELOPMENTAL STAGE; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HUMAN; INFERTILITY THERAPY; INTRACYTOPLASMIC SPERM INJECTION; LOGISTIC REGRESSION ANALYSIS; NIDATION; OVULATION INDUCTION; PREDICTION; PREGNANCY RATE; RETROSPECTIVE STUDY; TWIN PREGNANCY;

EID: 4544323551     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/deh385     Document Type: Article

References (32)

1. Bolton VN, Hawes SM, Taylor CT and Parsons JH (1989) Development of spare human preimplantation embryos in vitro: an analysis of the correlations among gross morphology, cleavage rates, and development to the blastocyst. J In Vitro Fertil Embryo Transfer 6,30-35.
2. Bos-Mikich A, Mattos ALG and Ferrari AN (2001) Early cleavage of human embryos: an effective method for predicting succesful IVF/ICSI outcome. Hum Reprod 16,2658-2661.
3. Cummins JM, Breen TM, Harrison KL, Shaw JM, Wilson LM and Hennessey JF (1986) A formula for scoring human embryo growth rates in in vitro fertilization: its value in predicting pregnancy and in comparison with visual estimates of embryo quality. J In Vitro Fertil Embryo Transfer 3,284-295.
4. Dumoulin JCM, Coonen E, Bras M, Van Wissen LCP, Ignoul-Vanvuchelen RCM, Bergers-Janssen JM, Derhaag JG, Geraedts JPM and Evers JLH (2000) Comparison of in vitro development of embryos originating from either conventional IVF or ICSI. Hum Reprod 15,402-409.
5. Dumoulin JCM, Coonen E, Bras M, Bergers-Janssen JM, Ignoul-Vanvuchelen RCM, Van Wissen LCP, Geraedts JPM and Evers JLH (2001) Embryo development and chromosomal anomalies after ICSI: effect of the injection procedure. Hum Reprod 16,306-312.
6. Elster N (2000) Less is more: the risks of multiple births. Fertil Steril 74, 617-623.
7. ESHRE Capri Workshop (2000) Multiple gestation pregnancy. Hum Reprod 15,1856-1864.
8. Fenwick J, Platteau P, Murdoch AP and Herbert M (2002) Time from insemination to first cleavage predicts developmental competence of human preimplantation embryos in vitro. Hum Reprod 17,407-412.
9. Gerris J, De Neubourg D, Mangelschots K, Van Royen E, Van de Meerssche M and Valkenburg M (1999) Prevention of twin pregnancy after in-vitro fertilization or intracytoplasmatic sperm injection based on strict embryo criteria: a prospective randomized clinical trial. Hum Reprod 14, 2581-2587.
10. Gerris J, De Neubourg D, Mangelschots K, Van Royen E, Vercruyssen M, Barudy-Vasquez J, Valkenburg M and Ryckaert G (2002) Elective single day 3 embryo transfer halves the twinning rate without decrease in the ongoing pregnancy rate of an IVF/ICSI programme. Hum Reprod 17, 2626-2631.
11. Giorgetti C, Terriou P, Auquier P, Hans E, Spach JL, Salzmann J and Roulier R (1995) Embryo score to predict implantation after in-vitro fertilization: band on 957 single embryo transfers. Hum Reprod 10, 2427-2431.
12. Kinzler WL, Ananth CV and Vintzileos AM (2000) Medical and economic effects of twin gestations. J Soc Gynecol Invest 7,321-327.
13. Land JA and Evers JL (2003) Risks and complications in assisted reproduction techniques: Report of an ESHRE consensus meeting. Hum Reprod 18,455-457.
14. Lundin K, Bergh C and Hardarson T (2001) Early embryo cleavage is a strong indicator of embryo quality in human IVF. Hum Reprod 16, 2652-2657.
15. Martikainen H, Tiitinen A, Tomas C, Tapanainen J, Orava M, Tuomivaara L, Vilska S, Hyden-Granskog C and Hovatta O (2001) One versus two embryo transfer after IVF and ICSI: a randomised study. Hum Reprod 16,1900-1903.
16. Nagy ZP, Liu J, Joris H, Devroey P and Van Steirteghem A (1994) Time-course of oocyte activation, pronucleus formation and cleavage in human oocytes fertilized by intracytoplasmic sperm injection. Hum Reprod 9, 1743-1748.
17. Nagy ZP, Janssenswillen C, Janssens R, De Vos A, Staessen C, Van de Velde H and Van Steirteghem AC (1998) Timing of oocyte activation, pronucleus formation and cleavage in humans after intracytoplasmic sperm injection (ICSI) with testicular spermatozoa and after ICSI or in-vitro fertilization on sibling oocytes with ejaculated spermatozoa. Hum Reprod 13,1606-1612.
18. Olivennes F (2000) Avoiding multiple pregnancies. Double trouble: yes a twin pregnancy is an adverse outcome. Hum Reprod 15,1663-1665.
19. Rienzi L, Ubaldi F, Iacobelli M, Ferrero S, Minasi MG, Martinez F, Tesarik J and Greco E (2002) Day 3 embryo transfer with combined evaluation at the pronuclear and cleavage stages compares favourably with day 5 blastocyst transfer. Hum Reprod 17,1852-1855.
20. Sakkas D, Shoukir Y, Chardonnens D, Grace Bianchi P and Campana A (1998) Early cleavage of human embryos to the two-cell stage after intracytoplasmic sperm injection as an indicator of embryo viability. Hum Reprod 13,182-187.
21. Sakkas D, Percival G, D'Arcy Y, Sharif K and Afnan M (2001) Assessment of early cleaving in vitro fertilized human embryos at the 2-cell stage before transfer improves embryo selection. Fertil Steril 76,1150-1156.
22. Salumets A, Hyden-Granskog C, Makinen S, Suikkari A, Tiitinen A and Tuuri T (2003) Early cleavage predicts the viability of human embryos in elective single embryo transfer procedures. Hum Reprod 18,821-825.
23. Scott L, Alvero R, Leondires M and Miller B (2000) The morphology of human pronuclear embryos is positively related to blastocyst development and implantation. Hum Reprod 15,2394-2403.
24. Shoukir Y, Campana A, Farley T and Sakkas D (1997) Early cleavage of in-vitro fertilized human embryos to the 2-cell stage: a novel indicator of embryo quality and viability. Hum Reprod 12,1531-1536.
25. Steer CV, Mills CL, Tan SL, Campbell S and Edwards RG (1992) The cumulative embryo score: a predictive embryo scoring technique to select the optimal number of embryos to transfer in an in-vitro fertilization and embryo transfer programme. Hum Reprod 7,117-119.
26. Tesarik J, Junca AM, Hazout A, Aubriot FX, Nathan C, Cohen-Bacrie P and Dumont-Hassan M (2000) Embryos with high implantation potential after intracytoplasmic sperm injection can be recognized by a simple, non-invasive examination of pronuclear morphology. Hum Reprod 15, 1396-1399.
27. Tsai YC, Chung MT, Sung YH, Tsai TF, Tsai YT and Lin LY (2002) Clinical value of early cleavage embryo. Int J Gynecol Obstet 76,293-297.
28. Van Royen E, Mangelschots K, De Neubourg D, Valkenburg M, Van de Meerssche M, Ryckaert G, Eestermans W and Gerris J (1999) Characterization of a top quality embryo, a step towards single-embryo transfer. Hum Reprod 14,2345-2349.
29. Van Royen E, Mangelschots K, Vercruyssen M, De Neubourg D, Valkenburg M, Ryckaert G and Gerris J (2003) Multinucleation in cleavage stage embryos. Hum Reprod 18,1062-1069.
30. Vilska S, Tiitinen A, Hyden-Granskog C and Hovatta O (1999) Elective transfer of one embryo results in an acceptable pregnancy rate and eliminates the risk of multiple birth. Hum Reprod 14,2392-2395.
31. Witterner C, Bettahar-Lebugle K, Ohl J, Rongieres C, Nisand I and Gerlinger P (2000) Zygote evaluation: an efficient tool for embryo selection. Hum Reprod 15,2591-2597.
32. Ziebe S, Petersen K, Lindenberg S, Andersen AG, Gabrielsen A and Andersen AN (1997) Embryo morphology or cleavage stage: how to select the best embryos for transfer after in-vitro fertilization. Hum Reprod 12,1545-1549.