Gene gun immunization with clinically relevant allergens aggravates allergen induced pathology and is contraindicated for allergen immunotherapy

Molecular Immunology

Volumn 44, Issue 8, 2007, Pages 1879-1887

  Scheiblhofer, Sandra ^a   Stoecklinger, Angelika ^a   Gruber, Christina ^a   Hauser Kronberger, Cornelia ^a   Alinger, Beate ^a   Hammerl, Peter ^a   Thalhamer, Josef ^a   Weiss, Richard ^a  

^a UNIVERSITY OF SALZBURG   (Austria)

Author keywords

Bet v 1a; DNA based vaccine; Gene gun; Genetic immunization; Immunoglobulin E; Phl p 5; Type I allergy; Galactosidase

Indexed keywords

IMMUNOGLOBULIN G2; ALLERGEN; BET V 1 ALLERGEN, BETULA VERRUCOSA; BETA GALACTOSIDASE; DNA VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; PHL P V PROTEIN, PHLEUM PRATENSE; VEGETABLE PROTEIN;

ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASOPHIL; CELL INFILTRATION; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EVALUATION; GENE GUN; IMMUNIZATION; IMMUNOTHERAPY; LUNG LAVAGE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BAGG ALBINO MOUSE; BIOLISTIC TRANSFORMATION; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DESENSITIZATION; FEMALE; GENETICS; HYPERSENSITIVITY; IMMUNOLOGY; INSTRUMENTATION; LOEFFLER PNEUMONIA; LUNG; METHODOLOGY; PATHOLOGY; RAT; T LYMPHOCYTE;

ALLERGENS; ANIMALS; BASOPHILS; BETA-GALACTOSIDASE; BIOLISTICS; BRONCHOALVEOLAR LAVAGE FLUID; DESENSITIZATION, IMMUNOLOGIC; FEMALE; HYPERSENSITIVITY; IMMUNIZATION; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INTERFERON TYPE II; LUNG; MICE; MICE, INBRED BALB C; PLANT PROTEINS; PULMONARY EOSINOPHILIA; RATS; T-LYMPHOCYTES; VACCINES, DNA;

EID: 37849187323     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2006.09.023     Document Type: Article

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