Toll-like receptors in cancer

Oncogene

Volumn 27, Issue 2, 2008, Pages 158-160

  O'Neill, L A J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; CPG 28; CPG 7909; CYCLOOXYGENASE 2; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; IMIQUIMOD; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMO 2055; INTERLEUKIN 10 ANTIBODY; ISS 1018; LIGAND; MICRORNA; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

CANCER RESEARCH; DRUG RESEARCH; DRUG TARGETING; EDITORIAL; HUMAN; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; PRIORITY JOURNAL;

EID: 37849024002     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210903     Document Type: Editorial

References (8)

1. Anderson KV, Jurgens G, Nusslein-Volhard C. (1985). Establishment of dorsal-ventral polarity in the Drosophila embryo: genetic studies on the role of the Toll gene product. Cell 42: 779-789.
2. Doyle SL, O'Neill LAJ. (2006). Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity. Biochem Pharmacol 72: 1102-1113.
3. Hicks AM, Riedlinger G, Willingham MC, Alexander-Miller MA, Von Kap-Herr C, Pettenati MJ et al. (2006). Transferable anticancer innate immunity in spontaneous regression/complete resistance mice. Proc Natl Acad Sci USA 103: 7753-7758.
4. Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA. (1996). The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86: 973-983.
5. Medzhitov R, Janeway Jr CA. (1997). A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388: 394-397.
6. O'Neill LA. (2006). Targeting signal transduction as a strategy to treat inflammatory diseases. Nat Rev Drug Discov 5: 549-563.
7. O'Neill LA, Bowie AG. (2007). The family of five: TIR domain containing adapters in TLR signalling. Nat Rev Immunol 7: 353-364.
8. Uehori J, Matsumoto M, Tsuji S, Akazawa T, Takeuchi O, Akira S et al. (2003). Simultaneous blocking of human Toll-like receptors 2 and 4 suppresses myeloid dendritic cell activation induced by Mycobacterium bovis bacillus Calmette-Guerin peptidoglycan. Infect Immun 71: 4238-4249.