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Volumn 26, Issue 1, 2008, Pages 28-34

Secretory expression of p53(N15)-Ant following lentivirus-mediated gene transfer induces cell death in human cancer cells

Author keywords

Cancer gene therapy; P53; Recombinant lentivirus; Secretory expression

Indexed keywords

HELIX LOOP HELIX PROTEIN; LENTIVIRUS VECTOR; PROTEIN P53;

EID: 37849010951     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.1080/07357900701681384     Document Type: Article
Times cited : (7)

References (20)
  • 1
    • 0035555650 scopus 로고    scopus 로고
    • Activation and activities of the p53 tumor suppressor protein
    • Balint, E.E.; Vousden, K.H. Activation and activities of the p53 tumor suppressor protein. Br. J. Cancer 2001, 85, 1813-1823.
    • (2001) Br. J. Cancer , vol.85 , pp. 1813-1823
    • Balint, E.E.1    Vousden, K.H.2
  • 2
    • 0034282102 scopus 로고    scopus 로고
    • An intact HDM2 RING-finger domain is required for nuclear exclusion of p53
    • Boyd, S.D.; Tsai, K.Y.; Jacks, T. An intact HDM2 RING-finger domain is required for nuclear exclusion of p53. Nat. Cell. Biol. 2000, 2, 563-568.
    • (2000) Nat. Cell. Biol , vol.2 , pp. 563-568
    • Boyd, S.D.1    Tsai, K.Y.2    Jacks, T.3
  • 3
    • 0034708458 scopus 로고    scopus 로고
    • Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
    • Fang, S.; Jensen, J.P.; Ludwig, R.L.; Vousden, K.H.; Weissman, A.M. Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53. J. Biol. Chem. 2000, 275(12), 8945-8951.
    • (2000) J. Biol. Chem , vol.275 , Issue.12 , pp. 8945-8951
    • Fang, S.1    Jensen, J.P.2    Ludwig, R.L.3    Vousden, K.H.4    Weissman, A.M.5
  • 4
    • 0034624678 scopus 로고    scopus 로고
    • Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase
    • Honda, R.; Yasuda, H. Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase. Oncogene 2000, 19(11), 1473-1476.
    • (2000) Oncogene , vol.19 , Issue.11 , pp. 1473-1476
    • Honda, R.1    Yasuda, H.2
  • 5
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt, Y.; Maya, R.; Kazaz, A.; Oren, M. Mdm2 promotes the rapid degradation of p53. Nature 1997, 387(6630), 296-299.
    • (1997) Nature , vol.387 , Issue.6630 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 6
    • 0030965946 scopus 로고    scopus 로고
    • Regulation of p53 stability by Mdm2
    • Kubbutat, M.H.; Jones, S.N.; Vousden, K.H. Regulation of p53 stability by Mdm2. Nature 1997, 387(6630), 299-303.
    • (1997) Nature , vol.387 , Issue.6630 , pp. 299-303
    • Kubbutat, M.H.1    Jones, S.N.2    Vousden, K.H.3
  • 7
    • 0037398860 scopus 로고    scopus 로고
    • Protecting p53 from degradation
    • Lain, S. Protecting p53 from degradation. Biochem Soc Trans. 2003, 31(3), 482-485.
    • (2003) Biochem Soc Trans , vol.31 , Issue.3 , pp. 482-485
    • Lain, S.1
  • 8
    • 0035940401 scopus 로고    scopus 로고
    • Kanovsky, M.; Raffo, A.; Drew, L.; Rosal, R.. Peptides from the amino terminal mdm2-binding domin of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells. Proc Natl Acad Sci U S A. 2001, 98 (22)1, 2438-12443.
    • Kanovsky, M.; Raffo, A.; Drew, L.; Rosal, R.. Peptides from the amino terminal mdm2-binding domin of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells. Proc Natl Acad Sci U S A. 2001, 98 (22)1, 2438-12443.
  • 9
    • 0037435045 scopus 로고    scopus 로고
    • Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site
    • Do, T.N.; Rosal, R.V.; Drew, L.; Raffo, A.J. Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site. Oncogene. 2003, 22(10), 1431-1444.
    • (2003) Oncogene , vol.22 , Issue.10 , pp. 1431-1444
    • Do, T.N.1    Rosal, R.V.2    Drew, L.3    Raffo, A.J.4
  • 11
    • 0242625915 scopus 로고    scopus 로고
    • Guoxi, Z.; Yu, Y.; Hongliang, Z.; Quanying, W.; Guangxiao, Y. Construction of expression vector for NT4 (Si)-ADNF fusion gene. J. Xi'an Jiaotong University (Medical Sciences). 2003, 24(5), 427-430. Chinese
    • Guoxi, Z.; Yu, Y.; Hongliang, Z.; Quanying, W.; Guangxiao, Y. Construction of expression vector for NT4 (Si)-ADNF fusion gene. J. Xi'an Jiaotong University (Medical Sciences). 2003, 24(5), 427-430. Chinese
  • 12
    • 0037430912 scopus 로고    scopus 로고
    • Neurotrophin-4 is required for tolerance to morphine in the mouse
    • Smith, D.J.; Leil, T.A.; Liu, X. Neurotrophin-4 is required for tolerance to morphine in the mouse. Neurosci Lett. 2003, 340(2), 103-106
    • (2003) Neurosci Lett , vol.340 , Issue.2 , pp. 103-106
    • Smith, D.J.1    Leil, T.A.2    Liu, X.3
  • 13
    • 0027207328 scopus 로고
    • Widespread and developmentally regulated expression of neurotrophin-4 mRNA in rat brain and peripheral tissues
    • Timmusk, T.; Belluardo, N.; Metsis, M.; Persson, H. Widespread and developmentally regulated expression of neurotrophin-4 mRNA in rat brain and peripheral tissues. Eur J Neurosci. 1993, 5(6), 605-613.
    • (1993) Eur J Neurosci , vol.5 , Issue.6 , pp. 605-613
    • Timmusk, T.1    Belluardo, N.2    Metsis, M.3    Persson, H.4
  • 14
    • 0026545268 scopus 로고    scopus 로고
    • Mammalian neurotrophin -4:structure, chromosomal localization, tissue distribution receptor specificity
    • Ip, N.Y.; Ibanez, C.F.; Nye, S.H.; McClain, J. Mammalian neurotrophin -4:structure, chromosomal localization, tissue distribution receptor specificity. Proc. Natl. Acad. Sci. USA 1997, 89(7), 3060-3064
    • (1997) Proc. Natl. Acad. Sci. USA , vol.89 , Issue.7 , pp. 3060-3064
    • Ip, N.Y.1    Ibanez, C.F.2    Nye, S.H.3    McClain, J.4
  • 15
    • 37849004995 scopus 로고    scopus 로고
    • The construction of NT4 (Si)-NAP fusion gene vector and its expression in Ecoli
    • Chinese
    • Yu, Y.; Jiang, W.; Xin, Y.; Senglin, H. The construction of NT4 (Si)-NAP fusion gene vector and its expression in Ecoli. Journal of Neurology. 2004, 37(3), 260-261. Chinese
    • (2004) Journal of Neurology , vol.37 , Issue.3 , pp. 260-261
    • Yu, Y.1    Jiang, W.2    Xin, Y.3    Senglin, H.4
  • 17
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini, L.; Blomer, U.; Gallay, P.; Ory, D.; Mulligan, R. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996, 272(5259), 263-267.
    • (1996) Science , vol.272 , Issue.5259 , pp. 263-267
    • Naldini, L.1    Blomer, U.2    Gallay, P.3    Ory, D.4    Mulligan, R.5
  • 18
    • 0031710033 scopus 로고    scopus 로고
    • A third-generation lentivirus vector with a conditional packaging system
    • Dull, T.; Zufferey, R.; Kelly, M.; Mandel, R.J. A third-generation lentivirus vector with a conditional packaging system. J. Virol. 1998, 72(11), 8463-8471.
    • (1998) J. Virol , vol.72 , Issue.11 , pp. 8463-8471
    • Dull, T.1    Zufferey, R.2    Kelly, M.3    Mandel, R.J.4
  • 19
    • 0030819379 scopus 로고    scopus 로고
    • Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
    • Zufferey, R.; Nagy, D.; Mandel, R.J.; Naldini, L. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat. Biotechnol. 1997, 15(9), 871-875
    • (1997) Nat. Biotechnol , vol.15 , Issue.9 , pp. 871-875
    • Zufferey, R.1    Nagy, D.2    Mandel, R.J.3    Naldini, L.4
  • 20
    • 13844255513 scopus 로고    scopus 로고
    • The role of alpha-helical structure in p53 peptides as a determinant for their mechanism of cell death: Necrosis versus apoptosiss
    • Rosal, R.; Brandt-Rauf, P.; Pincus, M.R.; Wang, H. The role of alpha-helical structure in p53 peptides as a determinant for their mechanism of cell death: necrosis versus apoptosiss. Adv. Drug Deliv. Rev. 2005, 57(4), 653-660.
    • (2005) Adv. Drug Deliv. Rev , vol.57 , Issue.4 , pp. 653-660
    • Rosal, R.1    Brandt-Rauf, P.2    Pincus, M.R.3    Wang, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.