The Mycobacterium avium subsp. paratuberculosis MAP3464 gene encodes an oxidoreductase involved in invasion of bovine epithelial cells through the activation of host cell Cdc42

Infection and Immunity

Volumn 76, Issue 1, 2008, Pages 170-178

  Alonso Hearn, Marta ^a   Patel, Dilip ^b   Danelishvili, Lia ^a   Meunier Goddik, Lisbeth ^a   Bermudez, Luiz E ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXIDOREDUCTASE; PROTEIN CDC42; PROTEIN MAP3985C; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BINDING AFFINITY; CELL ACTIVATION; COW; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENE LOCATION; HOST CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; INTERNALIZATION; INTESTINE MUCOSA; KIDNEY EPITHELIUM; MAP3464 GENE; MASS SPECTROMETRY; MYCOBACTERIUM AVIUM; MYCOBACTERIUM AVIUM PARATUBERCULOSIS; NONHUMAN; OPERON; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TRANSPOSON; WESTERN BLOTTING; WILD TYPE;

ANIMALS; CATTLE; CDC42 GTP-BINDING PROTEIN; CELL LINE; ENZYME ACTIVATION; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS; OXIDOREDUCTASES; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 37749028740     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01913-06     Document Type: Article

References (30)

1. Alonso, A., and G.-D. Portillo. 2004. Hijacking of eukaryotic functions by intracellular bacterial pathogens. Int. Microbiol. 7:181-191.
2. Alto, N. M., F. Shao, C. S. Lazar, R. L. Brost, G. Chua, S. Mattoo, S. A. McMahon, P. Ghosh, T. R. Hughes, C. Boone, and J. E. Dixon. 2006. Identification of a bacterial type III effector family with G protein mimicry functions. Cell 124:133-145.
3. Bannantine, J. P., R. G. Barletta, J. R. Stabel, M. L. Paustian, and V. Kapur. 2004. Application of the genome sequence to address concerns that Mycobacterium avium subspecies paratuberculosis might be a foodborne pathogen. Foodborne Pathog. Dis. 1:3-15.
4. Bannantine, J. P., J. F. Huntley, E. Miltner, J. R. Stabel, and L. E. Bermudez. 2003. The Mycobacterium avium subsp. paratuberculosis 35 kDa protein plays a role in invasion of bovine epithelial cells. Microbiology 149:2061-2069.
5. Chacon, O., L. E. Bermudez, and R. G. Barletta. 2004. Johne's disease, inflammatory bowel disease, and Mycobacterium paratuberculosis. Annu. Rev. Microbiol. 58:329-363.
6. Dam, T., L. Danelishvili, M. Wu, and L. E. Bermudez. 2006. The fadD2 gene is required for efficient Mycobacterium avium invasion of mucosal epithelial cells. J. Infect. Dis. 193:1135-1142.
7. Hultgren, S. J., F. Jacob-Dubuisson, C. H. Jones, and C. I. Branden. 1993. PapD and superfamily of periplasmic immunoglobulin-like pilus chaperones. Adv. Protein Chem. 44:99-123.
8. Jackson, M. W., and G. V. Plano. 1999. DsbA is required for stable expression of outer membrane protein YscC and for efficient Yop secretion in Yersinia pestis. J. Bacteriol. 181:5126-5130.
9. Linnabary, R. D., G. L. Meerdink, M. T. Collins, J. R. Stabel, R. W. Sweeney, M. K. Washington, S. J. Wells, R. J. Chiodini, D. Hansen, and R. H. Whitlock. 2001. Johne's disease in cattle, p. 1-10. Issue paper, vol. 17. Council for Agricultural Science and Technology, Ames, IA.
10. McGarvey, J. A., D. Wagner, and L. E. Bermudez. 2004. Differential gene expression in mononuclear phagocytes infected with pathogenic and non-pathogenic mycobacteria. Clin. Exp. Immunol. 136:490-500.
11. Miltner, E., K. Daroogheh, P. K. Mehta, S. L. Cirillo, J. D. Cirillo, and L. E. Bermudez. 2005. Identification of Mycobacterium avium genes that affect invasion of the intestinal epithelium. Infect. Immun. 73:4214-4221.
12. Molle, V., D. Soulat, J. M. Jault, C. Grangeasse, A. J. Cozzone, and J. F. Prost. 2004. Two FHA domains on an ABC transporter, Rv1747, mediate its phosphorylation by PknF, a Ser/Thr protein kinase from Mycobacterium tuberculosis. FEMS Microbiol. Lett. 234:215-223.
13. Momotani, E., D. L. Whipple, A. B. Thiermann, and N. F. Cheville. 1988. Role of M cells and macrophages in the entrance of Mycobacterium paratuberculosis into domes of ileal Peyer's patches in calves. Vet. Pathol. 25:131-137.
14. Ott, S. L., S. J. Wells, and B. A. Wagner. 1999. Herd-level economic losses associated with Johne's disease on US dairy operations. Prev. Vet. Med. 40:179-192.
15. Parker, A. E., and L. E. Bermudez. 1997. Expression of the green fluorescent protein (GFP) in Mycobacterium avium as a tool to study the interaction between mycobacteria and host cells. Microb. Pathog. 22:193-198.
16. Patel, D., L. Danelishvili, Y. Yamazaki, M. Alonso, M. L. Paustian, J. P. Bannantine, L. Meunier-Goddik, and L. E. Bermudez. 2006. The ability of Mycobacterium avium subsp. paratuberculosis to enter bovine epithelial cells is influenced by preexposure to a hyperosmolar environment and intracellular passage in bovine mammary epithelial cells. Infect. Immun. 74:2849-2855.
17. Peek, J. A., and R. K. Taylor. 1992. Characterization of a periplasmic thiol: disulfide interchange protein required for the functional maturation of secreted virulence factors of Vibrio cholerae. Proc. Natl. Acad. Sci. USA 89:6210-6214.
18. Rohatgi, R., L. Ma, H. Miki, M. Lopez, T. Kirchhausen, T. Takenawa, and M. W. Kirschner. 1999. The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell 97:221-231.
19. Sangari, F. J., J. Goodman, and L. E. Bermudez. 2000. Mycobacterium avium enters intestinal epithelial cells through the apical membrane, but not by the basolateral surface, activates small GTPase Rho and, once within epithelial cells, expresses an invasive phenotype. Cell. Microbiol. 2:561-568.
20. Secott, T. E., T. L. Lin, and C. C. Wu. 2004. Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein facilitates M-cell targeting and invasion through a fibronectin bridge with host integrins. Infect. Immun. 72:3724-3732.
21. Stender, S., A. Friebel, S. Linder, M. Rohde, S. Mirold, and W. D. Hardt. 2000. Identification of SopE2 from Salmonella typhimurium, a conserved guanine nucleotide exchange factor for Cdc42 of the host cell. Mol. Microbiol. 36:1206-1221.
22. Stott, K., K. Saito, D. J. Thiele, and V. Massey. 1993. Old Yellow Enzyme. The discovery of multiple isozymes and a family of related proteins. J. Biol. Chem. 268:6097-6106.
23. Tamme, R., E. Camp, R. D. Kortschak, and M. Lardelli. 2000. Nonspecific, nested suppression PCR method for isolation of unknown flanking DNA. BioTechniques 28:895-899:902.
24. Tran Van Nhieu, G., E. Caron, A. Hall, and P. J. Sansonetti. 1999. IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells. EMBO J. 18:3249-3262.
25. Verma, A., and G. M. Ihler. 2002. Activation of Rac, Cdc42 and other downstream signalling molecules by Bartonella bacilliformis during entry into human endothelial cells. Cell. Microbiol. 4:557-569.
26. Watarai, M., T. Tobe, M. Yoshikawa, and C. Sasakawa. 1995. Disulfide oxidoreductase activity of Shigella flexneri is required for release of Ipa proteins and invasion of epithelial cells. Proc. Natl. Acad. Sci. USA 92:4927-4931.
27. Yamazaki, Y., L. Danelishvili, M. Wu, M. Macnab, and L. E. Bermudez. 2006. Mycobacterium avium genes associated with the ability to form a biofilm. Appl. Environ. Microbiol. 72:819-825.
28. Yu, J., and J. S. Kroll. 1999. DsbA: a protein-folding catalyst contributing to bacterial virulence. Microbes Infect. 1:1221-1228.
29. Yu, J., S. McLaughlin, R. B. Freedman, and T. R. Hirst. 1993. Cloning and active site mutagenesis of Vibrio cholerae DsbA, a periplasmic enzyme that catalyzes disulfide bond formation. J. Biol. Chem. 268:4326-4330.
30. Zhang, H. Z., and M. S. Donnenberg. 1996. DsbA is required for stability of the type IV pilin of enteropathogenic Escherichia coli. Mol. Microbiol. 21:787-797.