Mycobacterium avium enters intestinal epithelial cells through the apical membrane, but not by the basolateral surface, activates small GTPase Rho and, once within epithelial cells, expresses an invasive phenotype

Cellular Microbiology

Volumn 2, Issue 6, 2000, Pages 561-568

  Sangari, Félix J ^a   Goodman, Joseph ^b   Bermudez, Luiz E ^a  

^a Kuzell Institute for Arthritis and Infectious Diseases   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; EGTAZIC ACID; GUANOSINE TRIPHOSPHATASE; PROTEIN CDC42; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; APICAL MEMBRANE; ARTICLE; ASSAY; BACTEREMIA; BACTERIAL GROWTH; BASOLATERAL MEMBRANE; CELL GROWTH; CELL INTERACTION; CELL INVASION; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVATION; FLUORESCENCE MICROSCOPY; GASTROINTESTINAL INFECTION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; MACROPHAGE; MONOLAYER CULTURE; MYCOBACTERIUM AVIUM; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL;

AIDS-RELATED OPPORTUNISTIC INFECTIONS; BACTERIAL ADHESION; CACO-2 CELLS; CELL LINE; CELL MEMBRANE; EPITHELIAL CELLS; HUMANS; INTESTINAL MUCOSA; MICROSCOPY, ELECTRON; MICROSCOPY, VIDEO; MYCOBACTERIUM AVIUM COMPLEX; MYCOBACTERIUM AVIUM-INTRACELLULARE INFECTION; RHO GTP-BINDING PROTEINS;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM; MYCOBACTERIUM AVIUM;

EID: 0034518803     PISSN: 14625814     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1462-5822.2000.00080.x     Document Type: Article

References (28)

1. Factors affecting invasion of HT-29 and HEp-2 epithelial cells by organisms of the Mycobacterium avium complex
2. An animal model of Mycobacterium avium complex disseminated infection after colonization of the intestinal tract
3. Growth within macrophages increases the efficiency of Mycobacterium avium in invading other macrophages by a complement receptor-independent pathway
4. Exposure to low oxygen tension and increased osmoladty enhance the ability of Mycobacterium avium to enter intestinal epithelial (HT-29) cells
5. Requirement Of Cdc42 for Salmonella-induced cytoskeletal and nuclear responses
6. Growth of Mycobacterium avium within environmental amoeba enhances virulence
7. Mycobacterium avium Mycobacterium intracellulare from the intestinal tracts of patients with the acquired immunodeficiency syndrome: Concepts regarding acquisition and pathogenesis
8. Molecular epidemiology techniques for the study of Mycobacterium avium complex infection
9. Salmonella interactions with polarized human intestinal Caco-2 epithelial cells
10. Penetration of Salmonella through a Madin-Darby canine k dney epithelial cell monolayer
11. Effect of cell polarization and differentiation on entry of Listeria monocytogenes into the enterocyte-like Caco-2 cell line
12. Mycobacterium avium complex infection in the acquired immunodeficiency syndrome
13. Interaction between Mycobacterim avium complex and intestinal mucosal cells in vivo
14. The Mycobacterium avium complex
15. Pathways for the penetration of enteroinvasive Yersinia into mammalian cells
16. Natural history of disseminated Mycobacterium avium complex infection in AIDS
17. Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches
18. Mycobacterium avium infection following oral challenge in mice is associated with delayed inflammatory response and results in intestinal necrosis
19. Identification of the integrin binding domain of the Yersinia pseudotuberculosis invasin protein
20. In vitro interaction of Mycobactedum avium with intestinal epithelial cells
21. Cytotoxicity for lung epithelial cells is a virulence-associated phenotype of Mycobacterium tuberculosis
22. Shigella flexneri enters human colonic Caco-2 epithelial cells through the basolateral pole
23. Differentiation of intestinal ceils in vitro
24. Enterocyte-like differentiation of the human colon carcinoma cell line, Caco-2 in culture
25. Ultrastructural study of Mycobacteriurn avium infection of HT29 human intestinal epithelial cells
26. Analysis of Mycobacterium avium complex isolates infecting multiple organs of AIDS patients using pulsed field gel electrophoresis
27. Persistent colonization of potable water as a source of Mycobacterium avium infection in AIDS