The chimeric cytokine Hyper-IL-6 enhances the efficiency of lentiviral gene transfer in hepatocytes both in vitro and in vivo

Biotechnology Letters

Volumn 30, Issue 2, 2008, Pages 215-220

  Picanço Castro, Virgínia ^a   Fontes, Aparecida Maria ^a   Heinz, Stefan ^b   Tonn, Torsten ^b   Covas, Dimas Tadeu ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Gene therapy; H IL6; Hepatocytes; Lentiviral vectors; Transduction efficiency

Indexed keywords

BIOLOGICAL ORGANS; CELL CULTURE; RATS; TOXICITY;

GENE THERAPY; LENTIVIRAL VECTORS; TRANSDUCTION EFFICIENCY;

GENE TRANSFER;

HYBRID PROTEIN; INTERLEUKIN 6;

ANIMAL; ARTICLE; CELL CULTURE; CELL LINE; CELL PROLIFERATION; CYTOLOGY; GENE TRANSFER; GENE VECTOR; GENETICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; LIVER CELL; METABOLISM; MOUSE; UPREGULATION;

ANIMALS; CELL LINE; CELL PROLIFERATION; CELLS, CULTURED; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEPATOCYTES; HIV; HUMANS; INTERLEUKIN-6; MICE; RECOMBINANT FUSION PROTEINS; UP-REGULATION;

LENTIVIRUS; MUS;

EID: 37549072554     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-007-9528-x     Document Type: Article

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