Role of protein kinase C on the expression of platelet-derived growth factor and endothelin-1 in the retina of diabetic rats and cultured retinal capillary pericytes

Diabetes

Volumn 52, Issue 3, 2003, Pages 838-845

  Yokota, Tamotsu ^a   Ma, Ronald C ^a   Park, Joong Yeol ^a   Isshiki, Keiji ^a   Sotiropoulos, Konstantinos B ^a   Rauniyar, Ravi K ^a   Bornfeldt, Karin E ^b   King, George L ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c JOSLIN DIABETES CENTER   (United States)

Author keywords

BRPC, bovine retinal pericytes; DMEM, Dulbecco's modified Eagle's medium; ET 1, endothelin 1; FBS, fetal bovine serum; MAPK, mitogen activated protein kinase; PDGF, platelet derived growth factor; PKC, protein kinase C; STZ, streptozotocin

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 6,7 DIMETHOXY 2 PHENYLQUINOXALINE; ENDOTHELIN 1; ENZYME INHIBITOR; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE C; RUBOXISTAURIN; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; DIABETES MELLITUS; DIABETIC ANGIOPATHY; DIABETIC RETINOPATHY; DISEASE COURSE; ENZYME ACTIVATION; ENZYME INDUCTION; GLUCOSE BLOOD LEVEL; MALE; MOLECULAR MECHANICS; NONHUMAN; PERICYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA; RETINA CAPILLARY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CAPILLARIES; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIN-1; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION; INDOLES; INSULIN; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOKINES; MALE; MALEIMIDES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-SIS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN; RETINA; RETINAL VESSELS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0037343260     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.52.3.838     Document Type: Article

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