-
1
-
-
27644572664
-
Glucocorticoid pathways in chronic obstructive pulmonary disease therapy
-
Adcock IM and Ito K. Glucocorticoid pathways in chronic obstructive pulmonary disease therapy. Proc Am Thorac Soc 2: 340-341, 2005.
-
(2005)
Proc Am Thorac Soc
, vol.2
, pp. 340-341
-
-
Adcock, I.M.1
Ito, K.2
-
2
-
-
1642493927
-
Antiinflammatory roles of peroxisome proliferator-activated receptor gamma in human alveolar macrophages
-
Asada K, Sasaki S, Suda T, Chida K, and Nakamura H. Antiinflammatory roles of peroxisome proliferator-activated receptor gamma in human alveolar macrophages. Am J Resp Crit Care Med 169: 145-146, 2004.
-
(2004)
Am J Resp Crit Care Med
, vol.169
, pp. 145-146
-
-
Asada, K.1
Sasaki, S.2
Suda, T.3
Chida, K.4
Nakamura, H.5
-
4
-
-
33748701308
-
Regulation of inflammation by PPARs: A future approach to treat lung inflammatory diseases?
-
Becker J, Delayre-Orthez C, Frossard N, and Pons F. Regulation of inflammation by PPARs: a future approach to treat lung inflammatory diseases? Fundam Clin Pharmacol 20: 429-447, 2006.
-
(2006)
Fundam Clin Pharmacol
, vol.20
, pp. 429-447
-
-
Becker, J.1
Delayre-Orthez, C.2
Frossard, N.3
Pons, F.4
-
5
-
-
33644748138
-
Peroxisome proliferator-activated receptor gamma agonists as therapy for chronic airway inflammation
-
Belvisi MG, Hele DJ, and Birrell MA. Peroxisome proliferator-activated receptor gamma agonists as therapy for chronic airway inflammation. Eur J Pharmacol 533: 101-109, 2006.
-
(2006)
Eur J Pharmacol
, vol.533
, pp. 101-109
-
-
Belvisi, M.G.1
Hele, D.J.2
Birrell, M.A.3
-
6
-
-
18844458812
-
PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: Implications for therapy of lung fibrosis
-
Burgess HA, Daugherty LE, Thatcher TH, Lakatos HF, Ray DM, Reddonet M, Phipps RP, and Sime PJ. PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis. Am J Physiol Lung Cell Mol Physiol 288: L1146-11453, 2005.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.288
-
-
Burgess, H.A.1
Daugherty, L.E.2
Thatcher, T.H.3
Lakatos, H.F.4
Ray, D.M.5
Reddonet, M.6
Phipps, R.P.7
Sime, P.J.8
-
7
-
-
0018129815
-
Possible mechanisms of emphysema in smokers. In vitro suppression of serum elastase-inhibitory capacity by fresh cigarette smoke and its prevention by antioxidants
-
Carp H and Janoff A. Possible mechanisms of emphysema in smokers. In vitro suppression of serum elastase-inhibitory capacity by fresh cigarette smoke and its prevention by antioxidants. Am Rev Respir Dis 118: 617-621, 1978.
-
(1978)
Am Rev Respir Dis
, vol.118
, pp. 617-621
-
-
Carp, H.1
Janoff, A.2
-
8
-
-
0035132330
-
PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
-
Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, and Evans RM. PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med 7: 48-52, 2001.
-
(2001)
Nat Med
, vol.7
, pp. 48-52
-
-
Chawla, A.1
Barak, Y.2
Nagy, L.3
Liao, D.4
Tontonoz, P.5
Evans, R.M.6
-
9
-
-
0022272160
-
Free-radical chemistry of cigarette smoke and its toxicological implications
-
Church DF and Pryor WA. Free-radical chemistry of cigarette smoke and its toxicological implications. Environ Health Perspect 64: 111-126, 1985.
-
(1985)
Environ Health Perspect
, vol.64
, pp. 111-126
-
-
Church, D.F.1
Pryor, W.A.2
-
11
-
-
33751257201
-
Smad3 signaling involved in pulmonary fibrosis and emphysema
-
Gauldie J, Kolb M, Ask K, Martin G, Bonniaud P, and Warburton D. Smad3 signaling involved in pulmonary fibrosis and emphysema. Proc Am Thorac Soc 3: 696-702, 2006.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 696-702
-
-
Gauldie, J.1
Kolb, M.2
Ask, K.3
Martin, G.4
Bonniaud, P.5
Warburton, D.6
-
12
-
-
0037428314
-
-
2 inhibits the expression of proinflammatory genes in human blood monocytes via a PPAR-gamma-independent mechanism. Biochem Biophys Res Commun 302: 415-420, 2003.
-
2 inhibits the expression of proinflammatory genes in human blood monocytes via a PPAR-gamma-independent mechanism. Biochem Biophys Res Commun 302: 415-420, 2003.
-
-
-
-
13
-
-
10744230015
-
Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-delta(12,14)-prostaglandin J(2)
-
Itoh K, Mochizuki M, Ishii Y, Ishii T, Shibata T, Kawamoto Y, Kelly V, Sekizawa K, Uchida K, and Yamamoto M. Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-delta(12,14)-prostaglandin J(2). Mol Cell Biol 24: 36-45, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 36-45
-
-
Itoh, K.1
Mochizuki, M.2
Ishii, Y.3
Ishii, T.4
Shibata, T.5
Kawamoto, Y.6
Kelly, V.7
Sekizawa, K.8
Uchida, K.9
Yamamoto, M.10
-
14
-
-
0034741358
-
Prostaglandin-J2 induces synthesis of interleukin-8 by endothelial cells in a PPAR-gamma-independent manner
-
Jozkowicz A, Dulak J, Prager M, Nanobashvili J, Nigisch A, Winter B, Weigel G, and Huk I. Prostaglandin-J2 induces synthesis of interleukin-8 by endothelial cells in a PPAR-gamma-independent manner. Prostaglandins Other Lipid Mediat 66: 165-177, 2001.
-
(2001)
Prostaglandins Other Lipid Mediat
, vol.66
, pp. 165-177
-
-
Jozkowicz, A.1
Dulak, J.2
Prager, M.3
Nanobashvili, J.4
Nigisch, A.5
Winter, B.6
Weigel, G.7
Huk, I.8
-
15
-
-
33750530167
-
2 as a potential endogenous regulator of redox-sensitive transcription factors
-
2 as a potential endogenous regulator of redox-sensitive transcription factors. Biochem Pharmacol 72: 1516-1528, 2006.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 1516-1528
-
-
Kim, E.H.1
Surh, Y.J.2
-
16
-
-
33750949369
-
Cigarette smoke induces proinflammatory cytokine release in primary airway epithelial cells but not in transformed alveolar epithelial cells
-
Kode A, Yang SR, and Rahman I. Cigarette smoke induces proinflammatory cytokine release in primary airway epithelial cells but not in transformed alveolar epithelial cells. Respir Res 7: 132, 2006.
-
(2006)
Respir Res
, vol.7
, pp. 132
-
-
Kode, A.1
Yang, S.R.2
Rahman, I.3
-
17
-
-
33646401792
-
Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species
-
Landar A, Zmijewski JW, Dickinson DA, Le Goffe C, Johnson MS, Milne GL, Zanoni G, Vidari G, Morrow JD, and Darley-Usmar VM. Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species. Am J Physiol Heart Cric Physiol 290: H1777-1787, 2006.
-
(2006)
Am J Physiol Heart Cric Physiol
, vol.290
-
-
Landar, A.1
Zmijewski, J.W.2
Dickinson, D.A.3
Le Goffe, C.4
Johnson, M.S.5
Milne, G.L.6
Zanoni, G.7
Vidari, G.8
Morrow, J.D.9
Darley-Usmar, V.M.10
-
18
-
-
33745686056
-
Peroxisome proliferators-activated receptor-gamma inhibits cigarette smoke solution-induced mucin production in human airway epithelial (NCI-H292) cells
-
Lee SY, Kang EJ, Hur GY, Jung KH, Jung HC, Lee SY, Kim JH, Shin C, In KH, Yoo SH, and Shim JJ. Peroxisome proliferators-activated receptor-gamma inhibits cigarette smoke solution-induced mucin production in human airway epithelial (NCI-H292) cells. Am J Physiol Lung Cell Mol Physiol 291: L84-90, 2006.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
Lee, S.Y.1
Kang, E.J.2
Hur, G.Y.3
Jung, K.H.4
Jung, H.C.5
Lee, S.Y.6
Kim, J.H.7
Shin, C.8
In, K.H.9
Yoo, S.H.10
Shim, J.J.11
-
19
-
-
9744220302
-
Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs
-
Marwick JA, Kirkham PA, Stevenson CS, Danahay H, Giddings J, Butler K, Donaldson K, Macnee W, and Rahman I. Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs. Am J Respir Cell Mol Biol 31: 633-642, 2004.
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 633-642
-
-
Marwick, J.A.1
Kirkham, P.A.2
Stevenson, C.S.3
Danahay, H.4
Giddings, J.5
Butler, K.6
Donaldson, K.7
Macnee, W.8
Rahman, I.9
-
20
-
-
21144456105
-
2 and Nrf2 pathways in protection against acute lung injury
-
2 and Nrf2 pathways in protection against acute lung injury. Am J Respir Crit Care Med 171: 1260-1266, 2005.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 1260-1266
-
-
Mochizuki, M.1
Ishii, Y.2
Itoh, K.3
Iizuka, T.4
Morishima, Y.5
Kimura, T.6
Kiwamoto, T.7
Matsuno, Y.8
Hegab, A.E.9
Nomura, A.10
Sakamoto, T.11
Uchida, K.12
Yamamoto, M.13
Sekizawa, K.14
-
21
-
-
0032702312
-
A comparative study of Mono Mac 6 cells, isolated mononuclear cells and Limulus amoebocyte lysate assay in pyrogen testing
-
Moesby L, Jensen S, Hansen EW, and Christensen JD. A comparative study of Mono Mac 6 cells, isolated mononuclear cells and Limulus amoebocyte lysate assay in pyrogen testing. Int J Pharm 191: 141-149, 1999.
-
(1999)
Int J Pharm
, vol.191
, pp. 141-149
-
-
Moesby, L.1
Jensen, S.2
Hansen, E.W.3
Christensen, J.D.4
-
22
-
-
10044241543
-
Oxidative stress and cigarette smoke alter chromatin remodeling but differentially regulate NF-kappaB activation and proinflammatory cytokine release in alveolar epithelial cells
-
Moodie FM, Marwick JA, Anderson CS, Szulakowski P, Biswas SK, Bauter MR, Kilty I, and Rahman I. Oxidative stress and cigarette smoke alter chromatin remodeling but differentially regulate NF-kappaB activation and proinflammatory cytokine release in alveolar epithelial cells. FASEB J 18: 1897-1899, 2004.
-
(2004)
FASEB J
, vol.18
, pp. 1897-1899
-
-
Moodie, F.M.1
Marwick, J.A.2
Anderson, C.S.3
Szulakowski, P.4
Biswas, S.K.5
Bauter, M.R.6
Kilty, I.7
Rahman, I.8
-
23
-
-
0033938477
-
The effect of peroxisome proliferator-activated receptor gamma (PPARgamma) on human monocyte function: PPARgamma ligands do not inhibit tumor necrosis factor-alpha release in human monocytic cell line THP-1
-
Naitoh T, Kitahara M, and Tsuruzoe N. The effect of peroxisome proliferator-activated receptor gamma (PPARgamma) on human monocyte function: PPARgamma ligands do not inhibit tumor necrosis factor-alpha release in human monocytic cell line THP-1. Cell Biol Toxicol 16: 131-135, 2000.
-
(2000)
Cell Biol Toxicol
, vol.16
, pp. 131-135
-
-
Naitoh, T.1
Kitahara, M.2
Tsuruzoe, N.3
-
24
-
-
13244279654
-
Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: Interactions with glucocorticoids and beta2-agonists
-
Nie M, Corbett L, Knox AJ, and Pang L. Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: interactions with glucocorticoids and beta2-agonists. J Biol Chem 280: 2550-2561, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 2550-2561
-
-
Nie, M.1
Corbett, L.2
Knox, A.J.3
Pang, L.4
-
25
-
-
0037373271
-
Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: Relevance for chronic obstructive pulmonary disease therapy
-
Patel HJ, Belvisi MG, Bishop-Bailey D, Yacoub MH, and Mitchell JA. Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy. J Immunol 170: 2663-2669, 2003.
-
(2003)
J Immunol
, vol.170
, pp. 2663-2669
-
-
Patel, H.J.1
Belvisi, M.G.2
Bishop-Bailey, D.3
Yacoub, M.H.4
Mitchell, J.A.5
-
26
-
-
33750620057
-
Oxidative stress and redox regulation of lung inflammation in COPD
-
Rahman I and Adcock IM. Oxidative stress and redox regulation of lung inflammation in COPD. Eur Resp J 28: 219-242, 2006.
-
(2006)
Eur Resp J
, vol.28
, pp. 219-242
-
-
Rahman, I.1
Adcock, I.M.2
-
27
-
-
33749506249
-
-
2 and ciglitazone induce human B lymphocyte and B cell lymphoma apoptosis by PPARgamma-independent mechanisms. J Immunol 177: 5068-5076, 2007.
-
2 and ciglitazone induce human B lymphocyte and B cell lymphoma apoptosis by PPARgamma-independent mechanisms. J Immunol 177: 5068-5076, 2007.
-
-
-
-
28
-
-
0031886864
-
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
-
Ricote M, Li AC, Willson TM, Kelly CJ, and Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 391: 79-82, 1998.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
29
-
-
0032698544
-
The macrophage in chronic obstructive pulmonary disease
-
Shapiro SD. The macrophage in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160: S29-32, 1999.
-
(1999)
Am J Respir Crit Care Med
, vol.160
-
-
Shapiro, S.D.1
-
31
-
-
33845468172
-
Peroxisome proliferator-activated receptor-gamma agonists as potential anti-inflammatory agents in asthma and chronic obstructive pulmonary disease
-
Spears M, McSharry C, and Thomson NC. Peroxisome proliferator-activated receptor-gamma agonists as potential anti-inflammatory agents in asthma and chronic obstructive pulmonary disease. Clin Exp Allergy 36: 1494-1504, 2006.
-
(2006)
Clin Exp Allergy
, vol.36
, pp. 1494-1504
-
-
Spears, M.1
McSharry, C.2
Thomson, N.C.3
-
32
-
-
33745728358
-
Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages
-
Yang SR, Chida AS, Bauter MR, Shafiq N, Seweryniak K, Maggirwar SB, Kilty I, and Rahman I. Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages. Am J Physiol Lung Cell Mol Physiol 291: L46-57, 2006.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
-
-
Yang, S.R.1
Chida, A.S.2
Bauter, M.R.3
Shafiq, N.4
Seweryniak, K.5
Maggirwar, S.B.6
Kilty, I.7
Rahman, I.8
-
33
-
-
33847060910
-
Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: Implications for chronic inflammation and aging
-
Yang SR, Wright J, Bauter M, Seweryniak K, Kode A, and Rahman I. Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging. Am J Physiol Lung Cell Mol Physiol 292: L567-576, 2007.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Yang, S.R.1
Wright, J.2
Bauter, M.3
Seweryniak, K.4
Kode, A.5
Rahman, I.6
-
35
-
-
0023878330
-
Establishment of a human cell line (Mono-Mac6) with characteristics of mature monocytes
-
Ziegler-Heitbrock HW, Thiel E, Futterer A, Herzog V, Wirtz A, and Riethmuller G. Establishment of a human cell line (Mono-Mac6) with characteristics of mature monocytes. Int J Cancer 41: 456-461, 1988.
-
(1988)
Int J Cancer
, vol.41
, pp. 456-461
-
-
Ziegler-Heitbrock, H.W.1
Thiel, E.2
Futterer, A.3
Herzog, V.4
Wirtz, A.5
Riethmuller, G.6
-
36
-
-
17644405062
-
Peroxisome proliferator-activated receptor-γ is a new therapeutic target in sepsis and inflammation
-
Zingarelli B and Cook JA. Peroxisome proliferator-activated receptor-γ is a new therapeutic target in sepsis and inflammation. Shock 23: 393-399, 2005.
-
(2005)
Shock
, vol.23
, pp. 393-399
-
-
Zingarelli, B.1
Cook, J.A.2
|