Clinical progression of HIV infection: Role of NK cells

Scandinavian Journal of Immunology

Volumn 46, Issue 1, 1997, Pages 91-95

  Bruunsgaard, H ^a   Pedersen, C ^b   Skinhoj P ^a   Pedersen, B K ^a  

^a University of Copenhagen   (Denmark)

^b HVIDOVRE HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; CLINICAL ARTICLE; DISEASE ACTIVITY; DISEASE COURSE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; NATURAL KILLER CELL; PRIORITY JOURNAL; SEROCONVERSION;

EID: 0030753729     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1997.d01-98.x     Document Type: Article

References (28)

1. Lucia B, Jennings C, Cauda R, Ortona L, Landay AL. Evidence of a selective depletion of a CD16+CD56+CD8+ natural killer cell subset during HIV infection. Cytometry 1995;22:10-15.
2. Ullum H, Gøtzsche PC, Victor J, Dickmeiss E, Skinløj P, Pedersen BK. Defective natural immunity - an early manifestation of human immunodeficiency virus infection. J Exp Med 1995;182: 789-800.
3. Brenner BG, Dascal A, Margolese RG, Wainberg MA. Natural killer cell function in patients with acquired immunodeficiency syndrome and related diseases. J Leukoc Biol 1989;46:75-83.
4. Brenner BG, Gryllis C, Gornitsky M, Wainberg MA. Changes in natural immunity during the course of HIV-1 infection. Clin Exp Immunol 1993;93:142-8.
5. Brenner BG, Gryllis C, Wainherg MA. Role of antibody-dependent cellular cytotoxicity and lymphokine-activated killer cells in AIDS and related diseases. J Leukoc Biol 1991;50:628-40.
6. Scott Algara D, Vuillier F, Cayota A, Dighiero G. Natural killer (NK) cell activity during HIV infection: a decrease in NK activity is observed at the clonal level and is not restored after in vitro long-term culture of NK cells. Clin Exp Immunol 1992;90:181-7.
7. Mansour I, Doinel C, Rouger P. CD16+ NK cells decrease in all stages of HIV infection through a selective depletion of the CD16+ CD8+CD3- subset. AIDS Res Hum Retroviruses 1990;6: 1451-7.
8. Sirianni MC, Tagliaferri F, Aiuti F. Pathogenesis of the natural killer cell deficiency in AIDS. Immunol Today 1990;11:81-2.
9. Cai Q, Huang XL, Rappocciolo G, Rinaldo CRJ. Natural killer cell responses in homosexual men with early HIV infection. J Acquir Immune Defic Syndr 1990;3:669-76.
10. Plaeger Marshall S, Spina CA, Giorgi JV et al. Alterations in cytotoxic and phenotypic subsets of natural killer cells in acquired immune deficiency syndrome (AIDS). J Clin Immunol 1987;7:16-23.
11. Bonavida B, Katz J, Gottlieb M. Mechanism of defective NK cell activity in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. I. Defective trigger on NK cells for NKCF production by target cells, and partial restoration by IL 2. J Immunol 1986;137:1157-63.
12. Katz JD, Mitsuyasu R, Gottlieb MS, Lebow LT, Bonavida B. Mechanism of defective NK cell activity in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. II. Normal antibody-dependent cellular cytotoxicity (ADCC) mediated by effector cells defective in natural killer (NK) cytotoxicity. J Immunol 1987;139:55-60.
13. Chin TW, Plaeger Marshall S, Haas A, Ank BJ, Stiehm ER. Lymphokine-activated killer cells in primary immunodeficiencies and acquired immunodeficiency syndrome. Clin Immunol Immunopathol 1989;53:449-59.
14. Cauda R, Tumbarello M, Ortona L et al. Inhibition of lymphokine-activated killer activity during HIV infection: role of HIV-1 gp41 synthetic peptides. Nat Immun Cell Growth Regul 1990;9:366-75.
15. Gryllis C, Wainberg MA, Gornitsky M, Brenner B. Diminution of inducible lymphokine-activated killer cell activity in individuals with AIDS-related disorders. AIDS 1990;4:1205-12.
16. Hu PF, Hultin LE, Hultin P et al. Natural killer cell immunodefiency in HIV disease is manifest by profoundly decreased numbers of CD16+CD56+ cells and expansion of a population of CD16dimCD56- cells with low lytic activity. J Acquir Immune Defic Syndr Hum Retrovirol 1995;10:331-40.
17. Feinberg MB. Changing the natural history of HIV disease. Lancet 1996;348:239-46.
18. Haynes BF, Pantaleo G, Fauci AS. Toward an understanding of the correlates of protective immunity of HIV infection. Science 1996; 271:324-8.
19. Balter M. Elusive HIV-supressor factors found. Science 1995;270: 1560-1.
20. Ameisen JC, Estaquier J, Idziorek T. From AIDS to parasite infection: pathogen-mediated subversion of programmed cell death as a mechanism for immune dysregulation. Immunological Reviews 1994;142:9-51.
21. Clerici M, Shearer GM. A TH1 → TH2 switch is a critical step in the etiology of HIV infection. Immunol Today 1993;14:107-11.
22. Zanussi S, Simonelli C, D'Andrea M et al. CD8+ lymphocyte phenotype and cytokine production in long-term non-progressor and in progressor patients with HIV infection. Clin Exp Immunol 1996;105:220-4.
23. Lifson AR, Hessol NA, Buchbinder SP et al. Serum beta 2-microglobulin and prediction of progression to AIDS in HIV infection. Lancet 1992;339:1436-40.
24. Pedersen C, Kolby P, Sindrup J et al. The development of AIDS or AIDS-related conditions in a cohort of HIV antibody-positive homosexual men during a 3-year follow-up period. J Intern Med 1989;225:403-9.
25. Schlechter MT, Craib KJ, Le TN et al. Progression to AIDS and predictors of AIDS in seroprevalent and seroincident cohorts of homosexual men. AIDS 1989;3:347-53.
26. Gougeon M, Lecour H, Dulioust A et al. Programmed cell death in peripheral lymphocytes from HIV-infected persons. J Immunol 1996;156:3509-20.
27. Doweiko JP. Hematologic aspects of HIV infection. AIDS 1993;7:753-7.
28. Ullum H, Katzenstein T, Gerstoft J, Skinhøj P, Pedersen BK. Incresed plasma HIV-1 RNA levels are associated with low levels of non MHC class I restricted cytotoxicity. AIDS Res Hum Retroviruses 1996;13:255-6.