PDMS micro bead cage reactor for the detection of alpha feto protein (AFP)

Sensors and Actuators, B: Chemical

Volumn 128, Issue 2, 2008, Pages 349-358

  Jeong, Yongwon ^a   Choi, Kihwan ^b   Kim, Jinseok ^c   Chung, Doo Soo ^b   Kim, Byungkyu ^d   Kim, Hyeon Cheol ^b   Chun, Kukjin ^b  

^a Samsung Advanced Institute of Technology (SAIT)   (South Korea)

^b Seoul National University   (South Korea)

^c Korea Institute of Science and Technology   (South Korea)

^d Hankuk Aviation University   (South Korea)

Author keywords

AFP; PDMS; Pillar; Pretreatment; Reactor

Indexed keywords

FLOW RATE; PH EFFECTS; POLYDIMETHYLSILOXANE; PROTEINS; THERMAL EFFECTS;

ALPHA FETO PROTEIN (AFP); MICROCHIPS; REACTION CHAMBER; SURFACE IMMOBILIZATION;

CHEMICAL REACTORS;

EID: 37549043536     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.snb.2007.05.019     Document Type: Article

References (23)

1. Effenhauser C.S., Manz A., and Widmer H.M. Glass chips for high-speed capillary electrophoresis separations with submicrometer plate heights. Anal. Chem. 65 (1993) 2637-2642
2. Jacobson S.C., Koutny L.B., Hergenröder R., Moore A.W., and Ramsey J.M. Microchip capillary electrophoresis with an integrated postcolumn reactor. Anal. Chem. 66 (1994) 3472-3476
3. Fluri K., Fitzpatrick G., Chiem N., and Harrison D.J. Integrated capillary electrophoresis devices with an efficient postcolumn reactor in planar quartz and glass chips. Anal. Chem. 68 (1996) 4285-4290
4. Eijkel J.C.T., Prak A., Cowen S., Craston D.H., and Manz A. Micromachined heated chemical reactor for pre-column derivatisation. J. Chromatogr. A 815 (1998) 265-271
5. Kutter J.P., Ramsey R.S., Jacobson S.C., and Ramsey J.M. Determination of metal cations in microchip electrophoresis using on-chip complexation and sample stacking. J. Microcolumn Sep. 10 (1998) 313-319
6. Han A., Han K.-H., Mohanty S.K., and Bruno Frazier A. Microsystems for whole blood purification and electrophysiological analysis. J. Semicond. Technol. Sci. 5 (2005) 1-10
7. Sim T.S., Kim D.W., Kim E.-M., Joo H.S., Lee K.-N., Kim B.G., Kim Y.H., and Kim Y.-K. Fabrication, Estimation and Trypsin Digestion Experiment of the Thermally Isolated Micro Reactor for Bio-chemical Reaction. J. Semicond. Technol. Sci. 5 (2005) 149-158
8. Christel L.A., Petersen K., McMillan W., and Northrup M.A. Rapid, automated nucleic acid probe assays using silicon microstructures for nucleic acid concentration. J. Biomech. Eng. 121 (1999) 22-27
9. Khandurina J., Jacobson S.C., Waters L.C., Foote R.S., and Ramsey J.M. Microfabricated porous membrane structure for sample concentration and electrophoretic analysis. Anal. Chem. 71 (1999) 1815-1819
10. Khandurina J., McKnight T.E., Jacobson S.C., Waters L.C., Foote R.S., and Ramsey J.M. Integrated system for rapid PCR-based DNA analysis in microfluidic devices. Anal. Chem. 72 (2000) 2995-3000
11. Lin Y.-C., Ho H.-C., Tseng C.-K., and Hou S.-Q. A poly-methylmethacrylate electrophoresis microchip with sample preconcentrator. J. Micromech. Microeng. 11 (2001) 189-194
12. Ceriotti L., de Rooij N.F., and Verpoorte E. An integrated fritless column for on-chip capillary electrochromatography with conventional stationary phases. Anal. Chem. (2002) 639-647
13. Kittilsland G., and Stemme G. A sub-micron particle filter in silicon. Sens. Actuators A 23 (1990) 904-907
14. Chu W.-H., Chin R., Huen T., and Ferrari M. Silicon membrane nanofilters from sacrificial oxide removal. J. Microelectromech. Syst. 8 (1999) 34-42
15. Xing X., Yang J.M., Tai Y.C., and Ho C.M. Micromachined membrane particle filters. Sens. Actuators A 73 (1999) 184-191
16. Kuiper S., Wolferen H.V., Rijn C.V., Nijdam W., Krijnen G., and Elwenspoek M. Fabrication of microsieves with sub-micron pore size by laser interference lithography. J. Micromech. Microeng. 11 (2001) 33-37
17. Lichtenberg J., de Rooij N.F., and Verpoorte E. Sample pretreatment on microfabricated devices. Talanta 56 (2002) 233-266
18. Anderson H., van der Wijngaart W., and Stemme S. Micromachined filter-chamber array with passive valves for biochemical assays on beads. Electrophoresis 22 (2001) 249
19. Wang C., Oleschuk R., Ouchen F., Li J., Thibault P., and Harrison D.J. Integration of immobilized trypsin bead beds for protein digestion within a microfluidic chip incorporating capillary electrophoresis separations and an electrospray mass spectrometry interface. Rapid Commun. Mass Spectrom. 14 (2000) 1377-1383
20. Matsumura M., Ijichi M., Shiratori Y., Togo G., Hikiba Y., Inoue K., Kohara M., and Omata M. Simple quantitative assay of alpha-fetoprotein mRNA in liver tissue using the real-time detection polymerase chain reaction assay-its application for clinical use. Hepatol. Res. 20 (2001) 84-96
21. Senkans P.D., Biasi V.D., and Barrow D.A. Computational simulations of fluid flow dynamics and bead packing in solid phase extraction microsystems. Proc. Micro Total Anal. Syst. (2002) 76-78
22. Gizeli E., and Lowe Ed. C.R. Biomolecular Sensors (2002), Taylor & Francis
23. In: Crowther J.R. (Ed). ELISA: Theory and Practice (1995), Human Press, New Jersey