Ixolaris binding to factor X reveals a precursor state of factor Xa heparin-binding exosite

Protein Science

Volumn 17, Issue 1, 2008, Pages 146-153

  Monteiro, Robson Q ^a   Rezaie, Alireza R ^b   Bae, Jong Sup ^b   Calvo, Eric ^c   Andersen, John F ^c   Francischetti, Ivo M B ^c  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Heparin binding exosite; Intrinsic tenase; Proexosite; Prothrombinase; Tissue factor

Indexed keywords

BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; ENZYME PRECURSOR; HEPARIN; IXOLARIS; RECOMBINANT PROTEIN; TISSUE FACTOR PATHWAY INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; ENTHALPY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL FILTRATION CHROMATOGRAPHY; ISOTHERMAL TITRATION CALORIMETRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; STOICHIOMETRY;

ANIMALS; BINDING SITES; CALORIMETRY; CHROMATOGRAPHY, GEL; FACTOR VIIA; FACTOR X; FACTOR XA; HEPARIN; HUMANS; KINETICS; PROTEIN BINDING; SALIVARY PROTEINS; TICKS;

IXODIDA;

EID: 37549032692     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.073016308     Document Type: Article

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