Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 Å

Biochemical and Biophysical Research Communications

Volumn 366, Issue 1, 2008, Pages 15-22

  Mimasu, Shinya ^a   Sengoku, Toru ^b   Fukuzawa, Seketsu ^a   Umehara, Takashi ^b   Yokoyama, Shigeyuki ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b RIKEN YOKOHAMA INSTITUTE   (Japan)

Author keywords

Chromatin; Histone demethylase; Nucleosome; SWIRM domain; Transcription

Indexed keywords

HISTONE DEMETHYLASE LSD 1; METHYLTRANSFERASE; TRANYLCYPROMINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHROMATIN STRUCTURE; CRYSTAL STRUCTURE; ELECTRON; PRIORITY JOURNAL; TRANSCRIPTION INITIATION;

BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY; ENZYME ACTIVATION; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MONOAMINE OXIDASE INHIBITORS; OXIDOREDUCTASES, N-DEMETHYLATING; PROTEIN BINDING; TRANYLCYPROMINE;

EID: 37549022689     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.11.066     Document Type: Article

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