Modeling and stochastic simulation of the Ras/cAMP/PKA pathway in the yeast Saccharomyces cerevisiae evidences a key regulatory function for intracellular guanine nucleotides pools

Journal of Biotechnology

Volumn 133, Issue 3, 2008, Pages 377-385

  Cazzaniga, Paolo ^a   Pescini, Dario ^a   Besozzi, Daniela ^b   Mauri, Giancarlo ^a   Colombo, Sonia ^a   Martegani, Enzo ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

cAMP; Phosphodiesterase; Protein kinase A; Tau leaping

Indexed keywords

ALGORITHMS; CELLS; ENZYMES; GENE EXPRESSION; NUCLEOTIDES; STOCHASTIC MODELS;

CELL CYCLE PROGRESSION; GUANINE NUCLEOTIDES; PHOSPHODIESTERASE; PROTEIN KINASE; TAU-LEAPING;

YEAST;

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; RAS PROTEIN;

ALGORITHM; ARTICLE; CONTROLLED STUDY; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SIMULATION; STOCHASTIC MODEL; YEAST;

CATALYTIC DOMAIN; COMPUTER SIMULATION; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 1; FEEDBACK, BIOCHEMICAL; GENE DOSAGE; GUANINE NUCLEOTIDES; GUANOSINE TRIPHOSPHATE; INTRACELLULAR SPACE; MODELS, BIOLOGICAL; RAS PROTEINS; SACCHAROMYCES CEREVISIAE; STOCHASTIC PROCESSES;

SACCHAROMYCES CEREVISIAE;

EID: 37449025422     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2007.09.019     Document Type: Article

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