Helicobacter pylori cagA, vacA and iceA genotypes in western Indian population of Maharashtra with varied gastroduodenal diseases

Indian Journal of Pathology and Microbiology

Volumn 50, Issue 4, 2007, Pages 740-748

  Dharne, Mahesh Shantappa ^a   Munot, Hitendra ^a   Pujari, Rajesh ^a   Kakrani, Arjun Lal ^b   Patole, Milind Shivajirao ^a   Shouche, Yogesh Shripad ^a  

^a NATIONAL CENTRE FOR CELL SCIENCE   (India)

^b B J MEDICAL COLLEGE   (India)

Author keywords

16S rRNA; cagA; Gastrointestinal diseases; Helicobacter pylori; iceA; Polymerase chain reaction; vacA

Indexed keywords

BACTERIAL PROTEIN; CAGA PROTEIN; DNA 16S; ICEA PROTEIN; UNCLASSIFIED DRUG; VACUOLATING TOXIN;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ALLELE; ARTICLE; ATROPHIC GASTRITIS; BACTERIAL GENE; BACTERIUM DETECTION; BACTERIUM IDENTIFICATION; CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DISEASE PREDISPOSITION; DYSPEPSIA; FEMALE; GASTRODUODENAL ULCER; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL BIOPSY; GENE AMPLIFICATION; GENE IDENTIFICATION; GENETIC CORRELATION; GENETIC VARIABILITY; GENOTYPE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HISTOPATHOLOGY; HOUSEKEEPING GENE; HUMAN; HUMAN TISSUE; INDIA; INFECTION RATE; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; POLYMERASE CHAIN REACTION; SCORING SYSTEM; TISSUE SECTION;

ADOLESCENT; ADULT; AGE FACTORS; AGED; ANTIGENS, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BIOPSY; DNA, BACTERIAL; DNA, RIBOSOMAL; FEMALE; GASTROINTESTINAL DISEASES; GENES, BACTERIAL; GENOTYPE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INCIDENCE; INDIA; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; RNA, RIBOSOMAL, 16S;

EID: 37349122065     PISSN: 03774929     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Sicinschi LA, Correa P, Schneider BG. Comparison of genotyping of Helicobacter pylori cagA and vacA virulence genes from gastric biopsies and stool specimens. Helicobacter2003; 8:601-7.
2. Li L, Graham DY, Gutierrez O, et al. Genomic fingerprinting and genotyping of Helicobacter pylori strains from patients with duodenal ulcer or gastric cancer from different geographic regions. Dig Dis Sci2002; 47:2512-8.
3. Tovey FI, Hobsley M, Kaushik SP, et al. Duodenal gastric metaplasia and Helicobacter pylori infection in high and low duodenal ulcer-prevalent areas in India. J Gastroenterol Hepatol 2004; 19:497-505.
4. Hussain MA, Kauser F, Khan AA, et al. Implications of molecular genotyping of Helicobacter pylori isolates from different human populations by genomic fingerprinting of enterobacterial repetitive intergenic consensus regions for strain identification and geographic evolution. J Clin Microbiol2004; 42:2372-8.
5. Kauser F, Khan AA, Hussain MA, et al. The cag pathogenicity island of Helicobacter pylori is disrupted in the majority of patient isolates from different human populations. J Clin Microbiol2004; 42:5302-8.
6. Mishra KK, Srivastava S, Dwivedi PP, et al. Genotypes of Helicobacter pylori isolated from various acid peptic diseases in and around Lucknow. Curr Sci2002; 83:749-55.
7. Singh M, Prasad KN, Yachha SK, et al. Genotypes of Helicobacter pylori in children with upper abdominal pain. J Gastroenterol Hepatol2003; 18:1018-23.
8. Singh V, Trikha B, Nain CK, et al. Epidemiology of Helicobacter pylori and peptic ulcer in India. J Gastroenterol Hepatol2002; 17:659-65.
9. Faundez G, Troncoso M, Figureueroa G. Divergence of virulence factors of Helicobacter pylori among clinical isolates does not correlate with disease specificity. J Gastroenterol1999; 11:6-9.
10. Kodama K, Ito A, Nishizono A, Fujioka T, et al. Divergence of virulence factors of Helicobacter pylori among clinical isolates does not correlate with disease specificity. J Gastroenterol1999; 35:6-9.
11. Wu MS, Chen LT, Shun CT, et al. Promoter polymorphisms of tumor necrosis factor-alpha are associated with risk of gastric mucosa-associated lymphoid tissue lymphoma. Int J Cancer 2004; 110:695-700.
12. Brito CA, Silva LM, Juca N, et al. Prevalence of cagA and vacA genes in isolates from patients with Helicobacter pylori-associated gastroduodenal diseases in Recife, Pernambuco, Brazil. Mem Inst Oswaldo Cruz2003; 98:817-21.
13. Bulent K, Murat A, Esin A, et al. Association of CagA and VacA presence with ulcer and non-ulcer dyspepsia in a Turkish population. World J Gastroenterol2003; 9:1580-3.
14. Carroll IM, Ahmed N, Beesley SM, et al. Fine structure molecular typing of Irish Helicobacter pylori isolates and their genetic relatedness to strains from four different continents. J Clin Microbiol2003; 41:5755-9.
15. Chattopadhyay S, Datta S, Chowdhury A, et al. Virulence genes in Helicobacter pylori strains from West Bengal residents with overt H. pylori-associated disease and healthy volunteers. J Clin Microbiol2002; 40:2622-5.
16. Chattopadhyay S, Patra R, Ramamurthy T, et al. Multiplex PCR assay for rapid detection and genotyping of Helicobacter pylori directly from biopsy specimens. J Clin Microbiol2004; 42:2821-4.
17. Chaudhuri S, Chowdhury A, Datta S, et al. Anti-Helicobacter pylori therapy in India: differences in eradication efficiency associated with particular alleles of vacuolating cytotoxin (vacA) gene. J Gastroenterol Hepatol2003; 18:190-5.
18. Datta S, Chattopadhyay S, Chowdhury A, et al. Diagnosis and genotyping of Helicobacter pylori by polymerase chain reaction of bacterial DNA from gastric juice. J Gastroenterol Hepatol2005; 20:1253-9.
19. Ruzsovics A, Molnar B, Tulassay Z. Deoxyribonucleic acid-based diagnostic techniques to detect Helicobacter pylori. Aliment Pharmacol Ther2004; 19:1137-46.
20. Faundez G, Troncoso M, Figureueroa G. cagA and vacA in strains of Helicobacter pylori from ulcer and non-ulcerative dyspepsia patients. BMC Gastroenterol2002; 2:20.
21. Figureueiredo C, Machado JC, Pharoah P, et al. Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma. J Natl Cancer Inst 2002; 94:1680-7.
22. Figureueiredo C, Quint W, Nouhan N, et al. Assessment of Helicobacter pylori vacA and cagA genotypes and host serological response. J Clin Microbiol2001; 39:1339-44.
23. Park CY, Kwak M, Gutierrez O, et al. Comparison of genotyping Helicobacter pylori directly from biopsy specimens and genotyping from bacterial cultures. J Clin Microbiol2003; 41:3336-8.
24. Scholte GH, van Doorn LJ, Cats A, et al. Genotyping of Helicobacter pylori in paraffin-embedded gastric biopsy specimens: relation to histological parameters and effects on therapy. Am J Gastroenterol2002; 97:1687-95.
25. Sharma AK, Mittal S, Malvi SK. Association of Helicobacter pylori with peptic perforation in Chattisgarh region of India. Trop Gastroenterol2000; 21:42-3.
26. Scholte GH, van Doorn LJ, Quint WG, et al. Genotyping of Helicobacter pylori strains in formalin-fixed or Formaldehyde-sublimate-fixed paraffin-embedded gastric biopsy specimens. Diagn Mol Pathol2001; 10:166-70.
27. Golijow CD, Abba MC, Collura J, et al. Utilization of polymerase chain reaction for detection and genotyping of Helicobacter pylori in gastric biopsy using paraffin: a retrospective study. Acta Gastroenterol Latinoam2003; 33:193-8.
28. Liang S, Redlinger T. A protocol for isolating putative Helicobacter pylori from fecal specimens and genotyping using vacA alleles. Helicobacter2003; 8:561-7.
29. MacKay WG, Williams CL, McMillan M, et al. Evaluation of protocol using gene capture and PCR for detection of Helicobacter pylori DNA in feces. J Clin Microbiol2003; 41:4589-93.
30. Yamaoka Y, Kodama T, Kita M, et al. Relationship of vacA genotypes of Helicobacter pylori to cagA status, cytotoxin production, and clinical outcome. Helicobacter1998, 3:241-53.
31. Gunn MC, Stephens JC, Stewart JD, et al. Detection and typing of the virulence determinants cagA and vacA of Helicobacter pylori directly from biopsy DNA: are in vitro strains representative of in vivo strains? Eur J Gastroenterol Hepatol 1998; 10:683-7.
32. Oleastro M, Gerhard M, Lopes AI, et al. Helicobacter pylori virulence genotypes in Portuguese children and adults with gastroduodenal pathology. Eur J Clin Microbiol Infect Dis2003; 22:85-91.
33. Tiwari SK, Khan AA, Ahmed KS, et al. Polymerase chain reaction based analysis of the cytotoxin associated gene pathogenicity island of Helicobacter pylori from saliva: an approach for rapid molecular genotyping in relation to disease status. J Gastroenterol Hepatol2005; 20:1560-6.
34. Ashour AA, Magalhaes PP, Mendes EN, et al. Distribution of vacA genotypes in Helicobacter pylori strains isolated from Brazilian adult patients with gastritis, duodenal ulcer or gastric carcinoma. FEMS Immunol Med Microbiol2002; 12:173-8.
35. Kim SY, Woo CW, Lee YM, et al. Genotyping cagA, vacA subtype, iceA1, and babA of Helicobacter pylori isolates from Korean patients, and their association with gastroduodenal diseases. J Korean Med Sci2001; 16:579-84.
36. Kodama K, Ito A, Nishizono A, et al. Genetic characterization of Helicobacter pylori isolates from an Argentinean adult population based on cag pathogenicity island right-end motifs, lspA-glmM polymorphism and iceA and vacA genotypes. Clin Microbiol Infect2004; 10:811-9.
37. Lobo Gatti L, Agostinho Jn F, De Labio R, et al. Helicobacter pylori and cagA and vacA gene status in children from Brazil with chronic gastritis. Clin Exp Med2003; 3:166-72.
38. Maeda S, Ogura K, Yoshida H, et al. Major virulence factors, vacA and cagA, are commonly positive in Helicobacter pylori isolates in Japan. Gut1998; 42:338-53.
39. Mohammadi M, Oghalaie A, Mohajerani N, et al. Prevalence of Helicobacter pylori vacuolating cytotoxin and its allelic mosaicism as a predictive marker for Iranian dyspeptic patients. Bull Soc Pathol Exot2003; 96:3-5.
40. Mukhopadhyay AK, Kersulyte D, Jeong JY, et al. Distinctiveness of genotypes of Helicobacter pylori in Calcutta, India. J Bacteriol2000; 182:3219-27.
41. Bhattacharya SK, Berg DE, Nair GB. Virulence genes in Helicobacter pylori strains from West Bengal residents with overt H. pylori-associated disease and healthy volunteers. J Clin Microbiol2002; 40:2622-5.
42. Wirth T, Wang X, Linz B, et al. Distinguishing human ethnic groups by means of sequences from Helicobacter pylori: lessons from Ladakh. Proc Natl Acad Sci USA2004; 101:4746-51.
43. Bapat MR, Abraham P, Bhandarkar PV, et al. Acquisition of Helicobacter pylori infection and reinfection after its eradication are uncommon in Indian adults. Indian J Gastroenterol2000; 19:172-4.
44. Jain A, Buddhiraja S, Khurana B, et al. Risk factors for duodenal ulcer in north India. Trop Gastroenterol1999; 20:36-9.
45. Batmanabane V, Kate V, Ananthakrishnan N. Prevalence of Helicobacter pylori in patients with portal hypertensive gastropathy - a study from south India. Med Sci Monit2004; 10:CR133-6.
46. Bhasin DK, Kakkar N, Sharma BC, et al. Helicobacter pylori in gastric cancer in India. Trop gastroenterol 1999; 20: 70-2.
47. Datta S, Chowdhury A, Mukhopadhyay AK, et al. Molecular & evolutionary genetics & drug resistance of the gastric pathogen, Helicobacter pylori. Indian J Med Res2002; 115:73-101.
48. Thyagarajan SP, Ray P, Das BK, et al. Geographical difference in antimicrobial resistance pattern of Helicobacter pylori clinical isolates from Indian patients: Multicentric study. J Gastroenterol Hepatol2003; 18:1373-8.
49. Dhali GK, Garg PK, Sharma MP. Role of anti-Helicobacter pylori treatment in H. pylori-positive and cytoprotective drugs in H. pylori-negative, non-ulcer dyspepsia: results of a randomized, double blind, controlled trial in Asian Indians. J Gastroenterol Hepatol1999; 14:523-8.
50. Ghoshal UC, Das A, Management strategies for duodenal ulcer in India in the Helicobacter pylori era: an economic analysis. Natl Med J India 2002; 15: 140-4.
51. Harper CG, Feng Y, Xu S, et al. Helicobacter cetorum sp. nov., a urease-positive Helicobacter species isolated from dolphins and whales. J Clin Microbiol2002; 40:4536-43.
52. Falush D, Wirth T, Linz B, et al. Traces of human migrations in Helicobacter pylori populations. Science2003; 299:1582-5.