Role of the subchondral vascular system in endochondral ossification: Endothelial cells specifically derepress late differentiation in resting chondrocytes in vitro

Experimental Cell Research

Volumn 238, Issue 2, 1998, Pages 491-497

  Bittner, Katharina ^a   Vischer, Peter ^a   Bartholmes, Peter ^a   Bruckner, Peter ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; BONE BLOOD FLOW; BONE PLATE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL DIFFERENTIATION; CELL SPECIFICITY; CHICKEN; ENCHONDRAL OSSIFICATION; ENDOTHELIUM CELL; GROWTH PLATE; NONHUMAN; PRIORITY JOURNAL;

EID: 0032004869     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1997.3849     Document Type: Article

References (37)

1. Cancedda R., Descalzi-Cancedda F., Castagnola P. Chondrocyte differentiation. Int. Rev. Cytol. 159:1995;265-358.
2. Trueta J., Amato V. P. The vascular contribution to osteogenesis. III. Changes in the growth cartilage caused by experimentally induced ischemia. J. Bone Joint Surg. Br. Vol. 42:1960;571-587.
3. Brighton C. T. Morphology and biochemistry of the growth plate. Rheum. Dis. Clin. North Am. 13:1987;75-100.
4. Aharinejad S., Marks S. C. Jr., Bock P., Mason-Savas A., MacKay C. A., Larson E. K., Jackson M. E., Luftensteiner M., Wiesbauer E. CSF-1 treatment promotes angiogenesis in the metaphysis of osteopetrotic (toothless, tl) rats. Bone. 16:1995;315-324.
5. Pepper M. S., Montesano R., Vassalli J. D., Orci L. Chondrocytes inhibit endothelial sprout formation in vitro. Evidence for involvement of a transforming growth factor-β J. Cell. Physiol. 146:1991;170-179.
6. Tada K., Fukunaga T., Wakabayashi Y., Masumi S., Sato Y., Izumi H., Kohno K., Kuwano M. Inhibition of tubular morphogenesis in human microvascular endothelial cells by co-culture with chondrocytes and involvement of transforming growth factor-β: A model for avascularity in human cartilage. Biochim. Biophys. Acta Gen. Subj. 1201:1994;135-142.
7. Descalzi-Cancedda F., Melchiori A., Benelli R., Gentili C., Masiello L., Campanile G., Cancedda R., Albini A. Production of angiogenesis inhibitors and stimulators is modulated by cultured growth plate chondrocytes during in vitro differentiation: Dependence on extracellular matrix assembly. Eur. J. Cell Biol. 66:1995;60-68.
8. Alini M., Marriott A., Chen T., Abe S., Poole A. R. A novel angiogenic molecule produced at the time of chondrocyte hypertrophy during endochondral bone formation. Dev. Biol. 176:1996;124-132.
9. Carlevaro M. F., Albini A., Ribatti D., Gentili C., Benelli R., Cermelli S., Cancedda R., Descalzi-Cancedda F. Transferrin promotes endothelial cell migration and invasion: Implication in cartilage neovascularization. J. Cell Biol. 136:1997;1375-1384.
10. Böhme K., Winterhalter K. H., Bruckner P. Terminal differentiation of chondrocytes in culture is a spontaneous process and is arrested by transforming growth factor-β2 and basic fibroblast growth factor in synergy. Exp. Cell Res. 216:1995;191-198.
11. D'Angelo M., Pacifici M. Articular chondrocytes produce factors that inhibit maturation of sternal chondrocytes in serum-free agarose cultures: A TGF-β independent process. J. Bone Miner. Res. 12:1997;1368-1377.
12. Deng C. X., Wynshaw-Boris A., Zhou F., Kuo A., Leder P. Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell. 84:1996;911-921.
13. Castagnola P., Torella G., Cancedda R. Type X collagen synthesis by cultured chondrocytes derived from the permanent cartilaginous region of chick embryo sternum. Dev. Biol. 123:1987;332-337.
14. Tschan T., Hörler I., Houze Y., Winterhalter K. H., Richter C., Bruckner P. Resting chondrocytes in culture survive without growth factors, but are sensitive to toxic oxygen metabolites. J. Cell Biol. 111:1990;257-260.
15. Vischer P., Buddecke E. Alteration of glycosyltransferase activities during proliferation of cultivated arterial endothelial cells and smooth muscle cells. Exp. Cell. Res. 158:1985;15-28.
16. Dehm P., Prockop D. J. Synthesis and extrusion of collagen by freshly isolated cells from chick embryo tendon. Biochim. Biophys. Acta. 240:1971;358-369.
17. Sorokin L., Girg W., Gopfert T., Hallmann R., Deutzmann R. Expression of novel 400-kDa laminin-chains by mouse and bovine endothelial cells. Eur. J. Biochem. 223:1994;602-610.
18. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature. 227:1970;680-685.
19. Bruckner P., Hörler I., Mendler M., Houze Y., Winterhalter K. H., Eich-Bender S. G., Spycher M. A. Induction and prevention of chondrocyte hypertrophy in culture. J. Cell Biol. 109:1989;2537-2545.
20. Bessey A. O., Lowry O. H., Brock M. J. A method for the rapid determination of alkaline phosphatase with five cubic millimeters of serum. J. Biol. Chem. 164:1946;321-329.
21. Jacobson M. D., Weil M., Raff M. C. Programmed cell death in animal development. Cell. 88:1997;347-354.
22. McClure J., Bates G. P., Rowston H., Grant M. E. A comparison of the morphological, histochemical and biochemical features of embryonic chick sternal chondrocytes in vivo with chondrocytes cultured in three-dimensional collagen gels. Bone Miner. 3:1988;235-247.
23. Böhme K., Conscience-Egli M., Tschan T., Winterhalter K. H., Bruckner P. Induction of proliferation or hypertrophy of chondrocytes in serum-free culture. The role of insulin-like growth factor-I, insulin, or thyroxine. J. Cell Biol. 116:1992;1035-1042.
24. Quarto R., Campanile G., Cancedda R., Dozin B. Thyroid hormone, insulin, and glucocorticoids are sufficient to support chondrocyte differentiation to hypertrophy - A serum-free analysis. J. Cell Biol. 119:1992;989-995.
25. Ballock R. T., Reddi A. H. Thyroxine is the serum factor that regulates morphogenesis of columnar cartilage from isolated chondrocytes in chemically defined medium. J. Cell Biol. 126:1994;1311-1318.
26. Amizuka N., Warshawsky H., Henderson J. E., Goltzman D., Karaplis A. C. Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation. J. Cell Biol. 126:1994;1611-1623.
27. Weir E. C., Philbrick W. M., Amling M., Neff L. A., Baron R., Broadus A. E. Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation. Proc. Natl. Acad. Sci. USA. 93:1996;10240-10245.
28. Vortkamp A., Lee K., Lanske B., Segre G. V., Kronenberg H. M., Tabin C. J. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science. 273:1996;613-622.
29. Kato Y., Iwamoto M. Fibroblast growth factor is an inhibitor of chondrocyte terminal differentiation. J. Biol. Chem. 265:1990;5903-5909.
30. Iwamoto M., Shimazu A., Nakashima K., Suzuki F., Kato Y. Reduction in basic fibroblast growth factor receptor is coupled with terminal differentiation of chondrocytes. J. Biol. Chem. 266:1991;461-467.
31. Rousseau F., Bonaventure J., Legeal-Mallet L., Pelet A., Rozet J.-M., Maroteaux P., Le Merrer M., Munnich A. Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia. Nature. 371:1994;252-254.
32. Shiang R., Thompson L. M., Zhu Y.-Z., Church D. M., Fielder T. J., Bocian M., Winokur S. T., Wasmuth J. J. Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia. Cell. 78:1994;335-342.
33. Klagsbrun M., D'Amore P. A. Regulators of angiogenesis. Annu. Rev. Physiol. 53:1991;217-239.
34. von der Mark K., Kirsch T., Nerlich A., Kuss A., Weseloh G., Glückert K., Stöss H. Type X collagen synthesis in human osteoarthritic cartilage - Indication of chondrocyte hypertrophy. Arthritis Rheum. 35:1992;806-811.
35. Aigner T., Bertling W., Stöss H., Weseloh G., von der Mark K. Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage. J. Clin. Invest. 91:1993;829-837.
36. Aigner T., Glückert K., von der Mark K. Activation of fibrillar collagen synthesis and phenotypic modulation of chondrocytes in early human osteoarthritic cartilage lesions. Osteoarthritis Cartilage. 5:1997;183-189.
37. Mayne, R. van der Rest, M. Bruckner, P. Schmid, T. 1995, Approaches for isolating and characterizing the collagens of cartilage (types II, IX, X, and XI) and the type IX-related collagens of other tissues, In, Extracellular matrix. A practical approach, 73, 97, Oxford University Press, Oxford, U.K.