Antiplasmodial structure-activity relationship of 3-trifluoromethyl-2-arylcarbonylquinoxaline 1,4-di-N-oxide derivatives

Experimental Parasitology

Volumn 118, Issue 1, 2008, Pages 25-31

  Marin, Adoración ^a   Moreira Lima, Lidia ^a,b   Solano, Beatriz ^a   Vicente, Esther ^a   Pérez Silanes, Silvia ^a   Maurel, Séverine ^c   Sauvain, Michel ^c   Aldana, Ignacio ^a   Monge, Antonio ^a   Deharo, Eric ^c  

^a UNIVERSITY OF NAVARRA   (Spain)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c Laboratoire de Pharmacochimie   (France)

Author keywords

Antiplasmodial; Plasmodium; Quinoxaline

Indexed keywords

2 (2 FURYLCARBONYL) 3 TRIFLUOROMETHY 1,4 QUINOXALINE DIOXIDE; 2 (2 THIENYLCARBONYL) 3 TRIFLUOROMETHYL 1,4 QUINOXALINE DIOXIDE; 2 (2 THIENYLCARBONYL) 3,7 DI(TRIFLUOROMETHYL) 1,4 QUINOXALINE DIOXIDE; 6,7 DICHLORO 2 (2 NAPHTHYLCARBONYL) 3 TRIFLUOROMETHYL 1,4 QUINOXALINE DIOXIDE; 7 CHLORO 2 (2 FURYLCARBONYL) 3 TRIFLUOROMETHY 1,4 QUINOXALINE DIOXIDE; 7 CHLORO 2 (2 NAPHTHYLCARBONYL) 3 TRIFLUOROMETHYL 1,4 QUINOXALINE DIOXIDE; 7 CHLORO 2 (2 THIENYLCARBONYL) 3 TRIFLUOROMETHYL 1,4 QUINOXALINE DIOXIDE; 7 FLUORO 2 (2 FURYLCARBONYL) 3 TRIFLUOROMETHY 1,4 QUINOXALINE DIOXIDE; 7 FLUORO 2 (2 NAPHTHYLCARBONYL) 3 TRIFLUOROMETHYL 1,4 QUINOXALINE DIOXIDE; 7 FLUORO 2 (2 THIENYLCARBONYL) 3 TRIFLUOROMETHYL 1,4 QUINOXALINE DIOXIDE; 7 METHOXY 2 (2 FURYLCARBONYL) 3 TRIFLUOROMETHY 1,4 QUINOXALINE DIOXIDE; 7 METHYL 2 (2 NAPHTHYLCARBONYL) 3 TRIFLUOROMETHYL 1,4 QUINOXALINE DIOXIDE; 7 METHYL 2 (2 THIENYLCARBONYL) 3 TRIFLUOROMETHYL 1,4 QUINOXALINE DIOXIDE; ANTIMALARIAL AGENT; CHLOROQUINE; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; PARASITE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; CELL LINE, TUMOR; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; PLASMODIUM FALCIPARUM; QUINOXALINES; STRUCTURE-ACTIVITY RELATIONSHIP; VERO CELLS;

PLASMODIUM FALCIPARUM;

EID: 37349062702     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2007.05.009     Document Type: Article

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