-
1
-
-
0000306390
-
Statins do more than just lower cholesterol
-
Vaughan CJ, Murphy MB, Buckley BM. Statins do more than just lower cholesterol. Lancet. 1996;348:1079-1082.
-
(1996)
Lancet
, vol.348
, pp. 1079-1082
-
-
Vaughan, C.J.1
Murphy, M.B.2
Buckley, B.M.3
-
2
-
-
0037380540
-
The power of statins: Aggressive lipid lowering
-
III25-III31
-
Stein EA. The power of statins: aggressive lipid lowering. Clin Cardiol. 2003;26:III25-III31.
-
(2003)
Clin Cardiol
, pp. 26
-
-
Stein, E.A.1
-
3
-
-
3342996744
-
Effect of atorvastatin on risk of recurrent cardiovascular events after an acute coronary syndrome associated with high soluble CD40 ligand in the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study
-
Kinlay S, Schwartz GG, Olsson AG, et al. Effect of atorvastatin on risk of recurrent cardiovascular events after an acute coronary syndrome associated with high soluble CD40 ligand in the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study. Circulation. 2004;110:386-391.
-
(2004)
Circulation
, vol.110
, pp. 386-391
-
-
Kinlay, S.1
Schwartz, G.G.2
Olsson, A.G.3
-
4
-
-
0031451344
-
Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase
-
Laufs U, Fata VL, Liao JK. Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase. J Biol Chem. 1997;272:31725-31729.
-
(1997)
J Biol Chem
, vol.272
, pp. 31725-31729
-
-
Laufs, U.1
Fata, V.L.2
Liao, J.K.3
-
5
-
-
0346736491
-
Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells
-
Hernandez-Perera O, Perez-Sala D, Navarro-Antolin J, et al. Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells. J Clin Invest. 1998;101:2711-2719.
-
(1998)
J Clin Invest
, vol.101
, pp. 2711-2719
-
-
Hernandez-Perera, O.1
Perez-Sala, D.2
Navarro-Antolin, J.3
-
6
-
-
0032555154
-
Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase
-
Endres M, Laufs U, Huang Z, et al. Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. Proc Nat Acad Sci USA. 1998;95:8880-8885.
-
(1998)
Proc Nat Acad Sci USA
, vol.95
, pp. 8880-8885
-
-
Endres, M.1
Laufs, U.2
Huang, Z.3
-
7
-
-
0032572043
-
Antiatherothrombotic properties of statins: Implications for cardiovascular event reduction
-
Rosenson RS, Tangney CC. Antiatherothrombotic properties of statins: implications for cardiovascular event reduction. JAMA. 1998;279:1643-1650.
-
(1998)
JAMA
, vol.279
, pp. 1643-1650
-
-
Rosenson, R.S.1
Tangney, C.C.2
-
8
-
-
0037207278
-
Statin inhibits interferon-gamma-induced expression of intercellular adhesion molecule-1 (ICAM-1) in vascular endothelial and smooth muscle cells
-
Chung HK, Lee IK, Kang H, et al. Statin inhibits interferon-gamma-induced expression of intercellular adhesion molecule-1 (ICAM-1) in vascular endothelial and smooth muscle cells. Exp Mol Med. 2002;34:451-461.
-
(2002)
Exp Mol Med
, vol.34
, pp. 451-461
-
-
Chung, H.K.1
Lee, I.K.2
Kang, H.3
-
9
-
-
0037082365
-
Improved fibrinolysis after 1-year treatment with HMG CoA reductase inhibitors in patients with coronary heart disease
-
Seljeflot I, Tonstad S, Hjermann I, et al. Improved fibrinolysis after 1-year treatment with HMG CoA reductase inhibitors in patients with coronary heart disease. Thromb Res. 2002;105:285-290.
-
(2002)
Thromb Res
, vol.105
, pp. 285-290
-
-
Seljeflot, I.1
Tonstad, S.2
Hjermann, I.3
-
10
-
-
2942720515
-
Beneficial cardiovascular pleiotropic effects of statins
-
109(Suppl 1):III39-III143
-
Davignon J. Beneficial cardiovascular pleiotropic effects of statins. Circulation. 2004;109(Suppl 1):III39-III143.
-
(2004)
Circulation
-
-
Davignon, J.1
-
11
-
-
0032488379
-
Increased thrombotic vascular events after change of statin
-
Thomas M, Mann J. Increased thrombotic vascular events after change of statin. Lancet. 1998;352:1830-1831.
-
(1998)
Lancet
, vol.352
, pp. 1830-1831
-
-
Thomas, M.1
Mann, J.2
-
12
-
-
0037177167
-
Withdrawal of statins increases event rates in patients with acute coronary syndromes
-
Heeschen C, Hamm CW, Laufs U, et al. Withdrawal of statins increases event rates in patients with acute coronary syndromes. Circulation. 2002;105:1446-1452.
-
(2002)
Circulation
, vol.105
, pp. 1446-1452
-
-
Heeschen, C.1
Hamm, C.W.2
Laufs, U.3
-
13
-
-
0344272945
-
Withdrawal of statins in patients with acute coronary syndromes
-
Heeschen C, Hamm CW, Laufs U, et al. Withdrawal of statins in patients with acute coronary syndromes. Circulation. 2003;107: e27.
-
(2003)
Circulation
, vol.107
-
-
Heeschen, C.1
Hamm, C.W.2
Laufs, U.3
-
14
-
-
6944240055
-
Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: National registry of myocardial infarction
-
Spencer FA, Fonarow GC, Frederick PD, et al. Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: national registry of myocardial infarction. Arch Intern Med. 2004;164:2162-2168.
-
(2004)
Arch Intern Med
, vol.164
, pp. 2162-2168
-
-
Spencer, F.A.1
Fonarow, G.C.2
Frederick, P.D.3
-
15
-
-
2542422856
-
Association of statin therapy with outcomes of acute coronary syndromes: The GRACE study
-
Spencer FA, Allegrone J, Goldberg RJ, et al. Association of statin therapy with outcomes of acute coronary syndromes: the GRACE study. Ann Intern Med. 2004;140:857-866.
-
(2004)
Ann Intern Med
, vol.140
, pp. 857-866
-
-
Spencer, F.A.1
Allegrone, J.2
Goldberg, R.J.3
-
16
-
-
33748100587
-
Statin withdrawal: Clinical implications and molecular mechanisms
-
Cubeddu LX, Seamon MJ. Statin withdrawal: clinical implications and molecular mechanisms. Pharmacotherapy. 2006;26:1288-1296.
-
(2006)
Pharmacotherapy
, vol.26
, pp. 1288-1296
-
-
Cubeddu, L.X.1
Seamon, M.J.2
-
17
-
-
0034687606
-
Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription
-
Laufs U, Endres M, Custodis F, et al. Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription. Circulation. 2000;102:3104-3110.
-
(2000)
Circulation
, vol.102
, pp. 3104-3110
-
-
Laufs, U.1
Endres, M.2
Custodis, F.3
-
18
-
-
0037178764
-
Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice
-
Vecchione C, Brandes RP. Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice. Circ Res. 2002;91:173-179.
-
(2002)
Circ Res
, vol.91
, pp. 173-179
-
-
Vecchione, C.1
Brandes, R.P.2
-
19
-
-
7644242146
-
Effects of statins on endothelium and signaling mechanisms
-
Endres M, Laufs U. Effects of statins on endothelium and signaling mechanisms. Stroke. 2004;35:2708-2711.
-
(2004)
Stroke
, vol.35
, pp. 2708-2711
-
-
Endres, M.1
Laufs, U.2
-
20
-
-
0141954208
-
Withdrawal of cerivastatin induces monocyte chemoattractant protein 1 and tissue factor expression in cultured vascular smooth muscle cells
-
Brandes RP, Beer S, Ha T, et al. Withdrawal of cerivastatin induces monocyte chemoattractant protein 1 and tissue factor expression in cultured vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2003;23:1794-1800.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 1794-1800
-
-
Brandes, R.P.1
Beer, S.2
Ha, T.3
-
21
-
-
33845633367
-
Effects of statin treatment and withdrawal on angiotensin II-induced phosphorylation of p38 MAPK and ERK1/2 in cultured vascular smooth muscle cells
-
Tristano AG, Castejon AM, Castro A, et al. Effects of statin treatment and withdrawal on angiotensin II-induced phosphorylation of p38 MAPK and ERK1/2 in cultured vascular smooth muscle cells. Biochem Biophys Res Commun. 2007;353:11-17.
-
(2007)
Biochem Biophys Res Commun
, vol.353
, pp. 11-17
-
-
Tristano, A.G.1
Castejon, A.M.2
Castro, A.3
-
22
-
-
0033635110
-
Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells
-
Touyz RM, Schiffrin EL. Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev. 2000;52:639-672.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 639-672
-
-
Touyz, R.M.1
Schiffrin, E.L.2
-
23
-
-
0030948534
-
Biological functions of angiotensin and its receptor
-
Matsusaka T, Ichikawa I. Biological functions of angiotensin and its receptor. Ann Rev Physiol. 1997;59:395-412.
-
(1997)
Ann Rev Physiol
, vol.59
, pp. 395-412
-
-
Matsusaka, T.1
Ichikawa, I.2
-
24
-
-
0028588486
-
Selective isolation of rat aortic wall layers and their cell types in culture-application to converting enzyme activity measurement
-
Battle T, Arnal JF, Challah M, et al. Selective isolation of rat aortic wall layers and their cell types in culture-application to converting enzyme activity measurement. Tissue Cell. 1994;26:943-955.
-
(1994)
Tissue Cell
, vol.26
, pp. 943-955
-
-
Battle, T.1
Arnal, J.F.2
Challah, M.3
-
25
-
-
0031600501
-
Growth factors and mitogen-activated protein kinases
-
Force T, Bonventre JV. Growth factors and mitogen-activated protein kinases. Hypertension. 1998;31:152-161.
-
(1998)
Hypertension
, vol.31
, pp. 152-161
-
-
Force, T.1
Bonventre, J.V.2
-
26
-
-
33846362954
-
Angiotensin II cell signaling: Physiological and pathological effects in the cardiovascular system
-
Mehta PK, Griendling KK. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol. 2007;292:C82-C97.
-
(2007)
Am J Physiol
, vol.292
-
-
Mehta, P.K.1
Griendling, K.K.2
-
27
-
-
0029861478
-
Angiotensin II stimulates MAP kinase kinase kinase activity in vascular smooth muscle cells, Role of Raf
-
Liao DF, Duff JL, Daum G, et al. Angiotensin II stimulates MAP kinase kinase kinase activity in vascular smooth muscle cells, Role of Raf. Circ Res. 1996;79:1007-1014.
-
(1996)
Circ Res
, vol.79
, pp. 1007-1014
-
-
Liao, D.F.1
Duff, J.L.2
Daum, G.3
-
28
-
-
0043075965
-
Up-regulation of vascular and renal mitogen-activated protein kinases in hypertensive rats is normalized by inhibitors of the Na+/Mg2+ exchanger
-
Touyz RM, Yao G. Up-regulation of vascular and renal mitogen-activated protein kinases in hypertensive rats is normalized by inhibitors of the Na+/Mg2+ exchanger. Clin Sci (Lond). 2003;105:235-242.
-
(2003)
Clin Sci (Lond)
, vol.105
, pp. 235-242
-
-
Touyz, R.M.1
Yao, G.2
-
29
-
-
0035571607
-
Downregulation of angiotensin II type 1 receptor by hydrophobic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in vascular smooth muscle cells
-
Ichiki T, Takeda K, Tokunou T, et al. Downregulation of angiotensin II type 1 receptor by hydrophobic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2001;21:1896-1901.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1896-1901
-
-
Ichiki, T.1
Takeda, K.2
Tokunou, T.3
-
30
-
-
0035122832
-
Inhibition of geranylgeranylation reduces angiotensin II-mediated free radical production in vascular smooth muscle cells: Involvement of angiotensin AT1 receptor expression and Rac1 GTPase
-
Wassmann S, Laufs U, Baumer AT, et al. Inhibition of geranylgeranylation reduces angiotensin II-mediated free radical production in vascular smooth muscle cells: involvement of angiotensin AT1 receptor expression and Rac1 GTPase. Mol Pharmacol. 2001;59:646-654.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 646-654
-
-
Wassmann, S.1
Laufs, U.2
Baumer, A.T.3
-
31
-
-
33745530252
-
Pathophysiological regulation of the AT1-receptor and implications for vascular disease
-
Wassmann S, Nickenig G. Pathophysiological regulation of the AT1-receptor and implications for vascular disease. J Hypertens Suppl. 2006;24:S15-21.
-
(2006)
J Hypertens Suppl
, vol.24
-
-
Wassmann, S.1
Nickenig, G.2
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