National academy of clinical biochemistry laboratory medicine practice guidelines: Point of care testing, oversight, and administration of cardiac biomarkers for acute coronary syndromes

Point of Care

Volumn 6, Issue 4, 2007, Pages 215-222

  Storrow, Alan B ^a   Apple, Fred S ^b   Wu, Alan H B ^c   Jesse, Robert L ^d   Francis, Gary S ^e   Christenson, Robert H ^f,k   Cannon, Christopher P ^g   Morrow, David A ^g   Newby, L Kristin ^h   Ravkilde, Jan ⁱ   Tang, Wilson ^j  

^a VANDERBILT UNIVERSITY   (United States)

^b HENNEPIN COUNTY MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^g BRIGHAM AND WOMEN S HOSPITAL   (United States)

^h DUKE UNIVERSITY MEDICAL CENTER   (United States)

ⁱ AARHUS UNIVERSITY HOSPITAL   (Denmark)

^j LERNER RESEARCH INSTITUTE   (United States)

^k UNIVERSITY OF MARYLAND MEDICAL CENTER   (United States)

more..

Author keywords

Acute coronary syndromes; Cardiac biomarkers; NACB; Point of care testing

Indexed keywords

EID: 37349020056     PISSN: 1533029X     EISSN: 15330303     Source Type: Journal    
DOI: 10.1097/poc.0b013e31809f8e34     Document Type: Review

References (86)

1. Tierney WM, Fitzgerald J, McHenry R, et al. Physicians' estimates of the probability of myocardial infarction in emergency room patients with chest pain. Med Decis Making. 1986;6:12-17.
2. Antman EM, Anbe DT, Armstrong PW, et al. ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of Patients With Acute Myocardial Infarction). Circulation. 2004;110:e82-e292.
3. Rusnak RA, Stair TO, Hansen K, et al. Litigation against the emergency physician: common features in cases of missed myocardial infarction. Ann Emerg Med. 1989;18:1029-1034.
4. Morrow DA, Cannon CP, Jesse RL, et al. National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: clinical characteristics and utilization of biochemical markers in acute coronary syndromes. Clin Chem. 2007;53:552-574.
5. Apple FS, Jesse RL, Newby LK, et al. National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: analytical issues for biochemical markers of acute coronary syndromes. Clin Chem. 2007;53:547-551.
6. Novis DA, Jones BA, Dale JC, et al. Biochemical markers of myocardial injury test turnaround time: a College of American Pathologists Q-Probes study of 7020 troponin and 4368 creatine kinase-MB determinations in 159 institutions. Arch Pathol Lab Med. 2004;128:158-164.
7. Storrow AB, Gibler WB. Chest pain centers: diagnosis of acute coronary syndromes. Ann Emerg Med. 2000;35:449-461.
8. Tatum JL, Jesse RL, Kontos MC, et al. Comprehensive strategy for the evaluation and triage of the chest pain patient. Ann Emerg Med. 1997;29:116-125.
9. Gibler WB, Runyon JP, Levy RC, et al. A rapid diagnostic and treatment center for patients with chest pain in the emergency department. Ann Emerg Med. 1995;25:1-8.
10. Farkouh ME, Smars PA, Reeder GS, et al. A clinical trial of a chest-pain observation unit for patients with unstable angina. Chest Pain Evaluation in the Emergency Room (CHEER) Investigators. N Engl J Med. 1998;339:1882-1888.
11. Fesmire FM. A rapid protocol to identify and exclude acute myocardial infarction: continuous 12-lead ECG monitoring with 2-hour delta CK-MB. Am J Emerg Med. 2000;18:698-702.
12. Fesmire FM, Hughes AD, Fody EP, et al. The Erlanger chest pain evaluation protocol: a one-year experience with serial 12-lead ECG monitoring, two-hour delta serum marker measurements, and selective nuclear stress testing to identify and exclude acute coronary syndromes. Ann Emerg Med. 2002;40:584-594.
13. Lewis S. Paradox, process and perception: the role of organizations in clinical practice guidelines development. CMAJ. 1995;153:1073-1077.
14. Braunwald E, Antman EM, Beasley JW, et al. ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction - summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Unstable Angina). J Am Coll Cardiol. 2002;40:1366-1374.
15. Mehta RH, Newby LK, Patel Y, et al. The impact of emergency department structure and care processes in delivering care for non-ST-segment elevation acute coronary syndromes. Am Heart J. 2006;152:648-660.
16. Peterson ED, Roe MT, Mulgund J, et al. Association between hospital process performance and outcomes among patients with acute coronary syndromes. JAMA. 2006;295:1912-1920.
17. Bhatt DL, Roe MT, Peterson ED, et al. Utilization of early invasive management strategies for high-risk patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE Quality Improvement Initiative. JAMA. 2004;292:2096-2104.
18. Hoekstra JW, Pollack CV Jr, Roe MT, et al. Improving the care of patients with non-ST-elevation acute coronary syndromes in the emergency department: the CRUSADE initiative. Acad Emerg Med. 2002;9:1146-1155.
19. Roe MT, Ohman EM, Pollack CV Jr, et al. Changing the model of care for patients with acute coronary syndromes. Am Heart J. 2003;146:605-612.
20. Azzazy HM, Christenson RH. Cardiac markers of acute coronary syndromes: is there a case for point-of-care testing? Clin Biochem. 2002;35:13-27.
21. Di Serio F, Lovero R, Leone M, et al. Integration between the tele-cardiology unit and the central laboratory: methodological and clinical evaluation of point-of-care testing cardiac marker in the ambulance. Clin Chem Lab Med. 2006;44:768-773.
22. Health Care Financing Administration. Revision of Troponin Policy, Medicare Part A. Dallas, TX: Health Care Financing Administration; 1998. Newsletter 004-98.
23. Bhatt DL, Topol EJ. Current role of platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes. JAMA. 2000;284:1549-1558.
24. Boden WE, O'Rourke RA, Crawford MH, et al. Outcomes in patients with acute non-Q-wave myocardial infarction randomly assigned to an invasive as compared with a conservative management strategy. Veterans Affairs Non-Q-Wave Infarction Strategies in Hospital (VANQWISH) Trial Investigators. N Engl J Med. 1998;338:1785-1792.
25. Cannon CP, Weintraub WS, Demopoulos LA, et al. Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofiban. N Engl J Med. 2001;344:1879-1887.
26. Roe MT, Christenson RH, Ohman EM, et al. A randomized, placebo-controlled trial of early eptifibatide for non-ST-segment elevation acute coronary syndromes. Am Heart J. 2003;146:993-998.
27. Cohn PF. Silent myocardial ischemia: an update. Adv Intern Med. 1989;34:377-392.
28. Lee-Lewandrowski E, Corboy D, Lewandrowski K, et al. Implementation of a point-of-care satellite laboratory in the emergency department of an academic medical center. Impact on test turnaround time and patient emergency department length of stay. Arch Pathol Lab Med. 2003;127:456-460.
29. National Heart Attack Alert Program Coordinating Committee. Emergency department: rapid identification and treatment of patients with acute myocardial infarction. 60 Minutes to Treatment Working Group. Ann Emerg Med. 1994;23:311-329.
30. Agewall S. Evaluation of point-of-care test systems using the new definition of myocardial infarction. Clin Biochem. 2003;36:27-30.
31. Antman EM, Grudzien C, Sacks DB. Evaluation of a rapid bedside assay for detection of serum cardiac troponin T. JAMA. 1995;273:1279-1282.
32. Apple FS, Anderson FP, Collinson P, et al. Clinical evaluation of the first medical whole blood, point-of-care testing device for detection of myocardial infarction. Clin Chem. 2000;46:1604-1609.
33. Apple FS, Christenson RH, Valdes R Jr, et al. Simultaneous rapid measurement of whole blood myoglobin, creatine kinase MB, and cardiac troponin I by the triage cardiac panel for detection of myocardial infarction. Clin Chem. 1999;45:199-205.
34. Apple FS, Ler R, Chung AY, et al. Point-of-care i-STAT cardiac troponin I for assessment of patients with symptoms suggestive of acute coronary syndrome. Clin Chem. 2006;52:322-325.
35. Brogan GX Jr, Bock JL, McCuskey CF, et al. Evaluation of cardiac STATus CK-MB/myoglobin device for rapidly ruling out acute myocardial infarction. Clin Lab Med. 1997;17:655-668.
36. Brogan GX Jr, Friedman S, McCuskey C, et al. Evaluation of a new rapid quantitative immunoassay for serum myoglobin versus CK-MB for ruling out acute myocardial infarction in the emergency department. Ann Emerg Med. 1994;24:665-671.
37. Collinson PO, Gerhardt W, Katus HA, et al. Multicentre evaluation of an immunological rapid test for the detection of troponin T in whole blood samples. Eur J Clin Chem Clin Biochem. 1996;34:591-598.
38. Collinson PO, John C, Lynch S, et al. A prospective randomized controlled trial of point-of-care testing on the coronary care unit. Ann Clin Biochem. 2004;41:397-404.
39. Heeschen C, Goldmann BU, Moeller RH, et al. Analytical performance and clinical application of a new rapid bedside assay for the detection of serum cardiac troponin I. Clin Chem. 1998;44:1925-1930.
40. Kost GJ, Tran NK. Point-of-care testing and cardiac biomarkers: the standard of care and vision for chest pain centers. Cardiol Clin. 2005;23:467-490, vi.
41. Muller-Bardorff M, Sylven C, Rasmanis G, et al. Evaluation of a point-of-care system for quantitative determination of troponin T and myoglobin. Clin Chem Lab Med. 2000;38:567-574.
42. Stubbs P, Collinson PO. Point-of-care testing: a cardiologist's view. Clin Chim Acta. 2001;311:57-61.
43. Wu AH, Smith A, Christenson RH, et al. Evaluation of a point-of-care assay for cardiac markers for patients suspected of acute myocardial infarction. Clin Chim Acta. 2004;346:211-219.
44. Yang Z, Min Zhou D. Cardiac markers and their point-of-care testing for diagnosis of acute myocardial infarction. Clin Biochem. 2006;39:771-780.
45. Storrow AB, Lindsell CJ, Collins SP, et al. Emergency department multimarker point-of-care testing reduces time to cardiac marker results without loss of diagnostic accuracy. Point of Care. 2006;5:132-136.
46. REACTT. Evaluation of a bedside whole-blood rapid troponin T assay in the emergency department. Rapid Evaluation by Assay of Cardiac Troponin T (REACTT) Investigators Study Group. Acad Emerg Med. 1997;4:1018-1024.
47. Altinier S, Zaninotto M, Mion M, et al. Point-of-care testing of cardiac markers: results from an experience in an emergency department. Clin Chim Acta. 2001;311:67-72.
48. Caragher TE, Fernandez BB, Jacobs FL, et al. Evaluation of quantitative cardiac biomarker point-of-care testing in the emergency department. J Emerg Med. 2002;22:1-7.
49. Collinson PO. The need for a point of care testing: an evidence-based appraisal. Scan J Clin Lab Invest. 1999;230:67-73.
50. McCord J, Nowak RM, McCullough PA, et al. Ninety-minute exclusion of acute myocardial infarction by use of quantitative point-of-care testing of myoglobin and troponin I. Circulation. 2001;104:1483-1488.
51. Newby LK, Storrow AB, Gibler WB, et al. Bedside multimarker testing for risk stratification in chest pain units: the Chest Pain Evaluation by Creatine Kinase-MB, Myoglobin, and Troponin I (CHECKMATE) study. Circulation. 2001;103:1832-1837.
52. Di Serio F, Antonelli G, Trerotoli P, et al. Appropriateness of point-of-care testing (POCT) in an emergency department. Clin Chim Acta. 2003;333:185-189.
53. Sieck S. The evolution of a new standard of hospital care: paradigm shift to the emergency department and the role of point-of-care testing. Point of Care. 2006;5:2-5.
54. Apple FS, Chung AY, Kogut ME, et al. Decreased patient charges following implementation of point-of-care cardiac troponin monitoring in acute coronary syndrome patients in a community hospital cardiology unit. Clin Chim Acta. 2006;370:191-195.
55. Singer AJ, Ardise J, Gulla J, et al. Point-of-care testing reduces length of stay in emergency department chest pain patients. Ann Emerg Med. 2005;45:587-591.
56. Schuchert A, Hamm C, Scholz J, et al. Prehospital testing for troponin T in patients with suspected acute myocardial infarction. Am Heart J. 1999;138:45-48.
57. Cawdery M, Burg MD. Emergency medicine career paths less traveled: cruise ship medicine, Indian health, and critical care medicine. Ann Emerg Med. 2004;44:79-83.
58. Kost GJ, Tran NK, Tuntideelert M, et al. Katrina, the tsunami, and point-of-care testing: optimizing rapid response diagnosis in disasters. Am J Clin Pathol. 2005;126:1-8.
59. Gomez MA, Anderson JL, Karagounis LA, et al. An emergency department-based protocol for rapidly ruling out myocardial ischemia reduces hospital time and expense: results of a randomized study (ROMIO). J Am Coll Cardiol. 1996;28:25-33.
60. Mueller C, Scholer A, Laule-Kilian K, et al. Use of B-type natriuretic peptide in the evaluation and management of acute dyspnea. N Engl J Med. 2004;350:647-654.
61. Wu AH, Clive JM. Impact of CK-MB testing policies on hospital length of stay and laboratory costs for patients with myocardial infarction or chest pain. Clin Chem. 1997;43:326-332.
62. Berger PB, Ellis SG, Holmes DR Jr, et al. Relationship between delay in performing direct coronary angioplasty and early clinical outcome in patients with acute myocardial infarction: results from the Global Use of Strategies to Open Occluded Arteries in Acute Coronary Syndromes (GUSTO-IIb) trial. Circulation. 1999;100:14-20.
63. Brodie BR, Stuckey TD, Wall TC, et al. Importance of time to reperfusion for 30-day and late survival and recovery of left ventricular function after primary angioplasty for acute myocardial infarction. J Am Coll Cardiol. 1998;32:1312-1319.
64. Cannon CP, Gibson CM, Lambrew CT, et al. Relationship of symptom-onset-to-balloon time and door-to-balloon time with mortality in patients undergoing angioplasty for acute myocardial infarction. JAMA. 2000;283:2941-2947.
65. Cox DA, Stone GW, Grines CL, et al. Comparative early and late outcomes after primary percutaneous coronary intervention in ST-segment elevation and non-ST-segment elevation acute myocardial infarction (from the CADILLAC trial). Am J Cardiol. 2006;98:331-337.
66. Diderholm E, Andren B, Frostfeldt G, et al. ST depression in ECG at entry indicates severe coronary lesions and large benefits of an early invasive treatment strategy in unstable coronary artery disease; the FRISC II ECG substudy. The Fast Revascularisation during InStability in Coronary artery disease. Eur Heart J. 2002;23:41-49.
67. Holmvang L, Clemmensen P, Lindahl B, et al. Quantitative analysis of the admission electrocardiogram identifies patients with unstable coronary artery disease who benefit the most from early invasive treatment. J Am Coll Cardiol. 2003;41:905-915.
68. Tardiff BE, Califf RM, Tcheng JE, et al. Clinical outcomes after detection of elevated cardiac enzymes in patients undergoing percutaneous intervention. IMPACT-II Investigators. Integrilin (eptifibatide) to Minimize Platelet Aggregation and Coronary Thrombosis-II. J Am Coll Cardiol. 1999;33:88-96.
69. Arendts G, MacKenzie J, Lee JK. Discharge planning and patient satisfaction in an emergency short-stay unit. Emerg Med Australas. 2006;18:7-14.
70. Boudreaux ED, Cruz BL, Baumann BM. The use of performance improvement methods to enhance emergency department patient satisfaction in the United States: a critical review of the literature and suggestions for future research. Acad Emerg Med. 2006;13:795-802.
71. Boudreaux ED, D'Autremont S, Wood K, et al. Predictors of emergency department patient satisfaction: stability over 17 months. Acad Emerg Med. 2004;11:51-58.
72. Boudreaux ED, Friedman J, Chansky ME, et al. Emergency department patient satisfaction: examining the role of acuity. Acad Emerg Med. 2004;11:162-168.
73. Davis BA, Kiesel CK, McFarland J, et al. Evaluating instruments for quality: testing convergent validity of the consumer emergency care satisfaction scale. J Nurs Care Qual. 2005;20:364-368.
74. Fermann GJ, Suyama J. Point of care testing in the emergency department. J Emerg Med. 2002;22:393-404.
75. Goodacre SW, Quinney D, Revill S, et al. Patient and primary care physician satisfaction with chest pain unit and routine care. Acad Emerg Med. 2004;11:827-833.
76. Huang JA, Lai CS, Tsai WC, et al. Determining factors of patient satisfaction for frequent users of emergency services in a medical center. J Chin Med Assoc. 2004;67:403-410.
77. Muntlin A, Gunningberg L, Carlsson M. Patients' perceptions of quality of care at an emergency department and identification of areas for quality improvement. J Clin Nurs. 2006;15:1045-1056.
78. Rodi SW, Grau MV, Orsini CM. Evaluation of a fast track unit: alignment of resources and demand results in improved satisfaction and decreased length of stay for emergency department patients. Qual Manag Health Care. 2006;15:163-170.
79. Taylor C, Benger JR. Patient satisfaction in emergency medicine. Emerg Med J. 2004;21:528-532.
80. Taylor D, Kennedy MP, Virtue E, et al. A multifaceted intervention improves patient satisfaction and perceptions of emergency department care. Int J Qual Health Care. 2006;18:238-245.
81. Vukmir RB. Customer satisfaction. Int J Health Care Qual Assur Inc Leadersh Health Serv. 2006;19:8-31.
82. Yildirim C, Kocoglu H, Goksu S, et al. Patient satisfaction in a university hospital emergency department in Turkey. Acta Medica (Hradec Kralove). 2005;48:59-62.
83. von Lode P. Point-of-care immunotesting: approaching the analytical performance of central laboratory methods. Clin Biochem. 2005;38:591-606.
84. Morrow DA. Evidence-based decision limits for cardiac troponin: low-level elevation and prognosis. Am Heart J. 2004;148:739-742.
85. Pham MX, Whooley MA, Evans GT Jr, et al. Prognostic value of low-level cardiac troponin-I elevations in patients without definite acute coronary syndromes. Am Heart J. 2004;148:776-782.
86. Wu AH. Point-of-care testing for conventional cardiac markers. Point of Care. 2006;5:20-24.