Cysteine pairs in the third intracellular loop of the muscarinic M 1 acetylcholine receptor play a role in agonist-induced internalization

Journal of Pharmacology and Experimental Therapeutics

Volumn 324, Issue 1, 2008, Pages 196-205

  Sawyer, Gregory W ^a   Ehlert, Frederick J ^b   Shults, Crystal A ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBACHOL; CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR STIMULATING AGENT; CYSTEINE; METHYLSCOPOLAMINE; MUSCARINIC M1 RECEPTOR; MUTANT PROTEIN; PHOSPHATIDYLINOSITIDE; PROLYLGLUTAMYLTHREONYLPROLYLPROLYLGLYCYLARGINYLCYSTEINYLCYSTEINYLARGINYLCYSTEINY LCYSTEINE; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; ARTICLE; CELL STRUCTURE; CHO CELL; DELETION MUTANT; DRUG RECEPTOR BINDING; HUMAN; HYDROLYSIS; INTERNALIZATION; LIGAND BINDING; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR AFFINITY; SITE DIRECTED MUTAGENESIS; WILD TYPE;

ANIMALS; CARBACHOL; CHO CELLS; CRICETINAE; CRICETULUS; CYSTEINE; HUMANS; HYDROLYSIS; MUTAGENESIS, SITE-DIRECTED; N-METHYLSCOPOLAMINE; PHOSPHATIDYLINOSITOLS; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, MUSCARINIC M1; TRANSFECTION;

EID: 37349008565     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.123695     Document Type: Article

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