Cell engineering of Escherichia coli allows high cell density accumulation without fed-batch process control

Bioprocess and Biosystems Engineering

Volumn 31, Issue 1, 2008, Pages 11-20

  Bäcklund, Emma ^a   Markland, Katrin ^a   Larsson, Gen ^a  

^a ALBANOVA UNIVERSITY CENTER   (Sweden)

Author keywords

Acetate formation; Fed batch technique; High cell density; Phosphotransferase system; PTS mutations; Recombinant product formation

Indexed keywords

ACETIC ACID; ESCHERICHIA COLI; GLUCOSE; GROWTH KINETICS; MUTAGENESIS; PROTEINS;

ACETATE FORMATION; FED BATCH TECHNIQUE; HIGH CELL DENSITY; PHOSPHOTRANSFERASE SYSTEMS (PTS); RECOMBINANT PRODUCT FORMATION;

CYTOLOGY;

ACETIC ACID; CARBOHYDRATE; GLUCOSE; OXYGEN; PHOSPHOENOLPYRUVATE; PHOSPHOENOLPYRUVATE SUGAR PHOSPHOTRANSFERASE;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BATCH CELL CULTURE; BIOENGINEERING; CELL DENSITY; ESCHERICHIA COLI; FED BATCH CULTURE; FED BATCH REACTOR; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS; WILD TYPE;

ACETIC ACID; CULTURE MEDIA; ESCHERICHIA COLI; GENETIC ENGINEERING; GLUCOSE; OXYGEN CONSUMPTION;

ESCHERICHIA COLI;

EID: 37249015436     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00449-007-0144-x     Document Type: Article

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