Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid

Stem Cell Research

Volumn 1, Issue 1, 2007, Pages 25-36

  Micallef, Suzanne J ^a   Li, Xueling ^a   Janes, Mary E ^a   Jackson, Steven A ^a   Sutherland, Robyn M ^b   Lew, Andrew M ^b   Harrison, Leonard C ^b   G Elefanty, Andrew ^a   Stanley, Edouard G ^a  

^a MONASH UNIVERSITY   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; BONE MORPHOGENETIC PROTEIN 4; GREEN FLUORESCENT PROTEIN; NICOTINAMIDE; RETINOIC ACID;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; DERIVATIZATION; ENDOCRINE CELL; ENDODERM; MOUSE; NONHUMAN; PANCREAS CELL; PANCREAS DUCT; PANCREATIC BUD LIKE STRUCTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 4; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; EMBRYO, MAMMALIAN; EMBRYONIC STEM CELLS; ENDOCRINE CELLS; GREEN FLUORESCENT PROTEINS; MICE; PANCREAS; STEM CELL TRANSPLANTATION; TRETINOIN;

EID: 37149047362     PISSN: 18735061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.scr.2007.06.002     Document Type: Article

References (55)

1. Abud H.E., Johnstone C.N., Tebbutt N.C., and Heath J.K. The murine A33 antigen is expressed at two distinct sites during development, the ICM of the blastocyst and the intestinal epithelium. Mech. Dev. 98 (2000) 111-114
2. Ahlgren U., Jonsson J., and Edlund H. The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice. Development 122 (1996) 1409-1416
3. Barnett L.D., and Kontgen F. Gene targeting in a centralized facility. Methods Mol. Biol. 158 (2001) 65-82
4. Ben-Haim N., Lu C., Guzman-Ayala M., Pescatore L., Mesnard D., Bischofberger M., Naef F., Robertson E.J., and Constam D.B. The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4. Dev. Cell 11 (2006) 313-323
5. Bevis B.J., and Glick B.S. Rapidly maturing variants of the Discosoma red fluorescent protein (DsRed). Nat. Biotechnol. 20 (2002) 83-87
6. Bhushan A., Itoh N., Kato S., Thiery J.P., Czernichow P., Bellusci S., and Scharfmann R. Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development 128 (2001) 5109-5117
7. Burkert U., von Ruden T., and Wagner E.F. Early fetal hematopoietic development from in vitro differentiated embryonic stem cells. New Biol. 3 (1991) 698-708
8. Chen Y., Pan F.C., Brandes N., Afelik S., Solter M., and Pieler T. Retinoic acid signaling is essential for pancreas development and promotes endocrine at the expense of exocrine cell differentiation in Xenopus. Dev. Biol. 271 (2004) 144-160
9. Chiang M.K., and Melton D.A. Single-cell transcript analysis of pancreas development. Dev. Cell 4 (2003) 383-393
10. D'Amour K.A., Agulnick A.D., Eliazer S., Kelly O.G., Kroon E., and Baetge E.E. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat. Biotechnol. 23 (2005) 1534-1541
11. D'Amour K.A., Bang A.G., Eliazer S., Kelly O.G., Agulnick A.D., Smart N.G., Moorman M.A., Kroon E., Carpenter M.K., and Baetge E.E. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat. Biotechnol. 24 (2006) 1392-1401
12. Doetschman T.C., Eistetter H., Katz M., Schmidt W., and Kemler R. The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J. Embryol. Exp. Morphol. 87 (1985) 27-45
13. Dosch R., Gawantka V., Delius H., Blumenstock C., and Niehrs C. Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus. Development 124 (1997) 2325-2334
14. Fehling H.J., Lacaud G., Kubo A., Kennedy M., Robertson S., Keller G., and Kouskoff V. Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation. Development 130 (2003) 4217-4227
15. Fujiwara T., Dunn N.R., and Hogan B.L. Bone morphogenetic protein 4 in the extraembryonic mesoderm is required for allantois development and the localization and survival of primordial germ cells in the mouse. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 13739-13744
16. Gouon-Evans V., Boussemart L., Gadue P., Nierhoff D., Koehler C.I., Kubo A., Shafritz D.A., and Keller G. BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm. Nat. Biotechnol. 24 (2006) 1402-1411
17. Gurdon J.B., and Bourillot P.Y. Morphogen gradient interpretation. Nature 413 (2001) 797-803
18. Hebrok M., Kim S.K., and Melton D.A. Notochord repression of endodermal Sonic hedgehog permits pancreas development. Genes Dev. 12 (1998) 1705-1713
19. Holland A.M., Micallef S.J., Li X., Elefanty A.G., and Stanley E.G. A mouse carrying the green fluorescent protein gene targeted to the Pdx1 locus facilitates the study of pancreas development and function. Genesis 44 (2006) 304-307
20. Johansson B.M., and Wiles M.V. Evidence for involvement of activin A and bone morphogenetic protein 4 in mammalian mesoderm and hematopoietic development. Mol. Cell. Biol. 15 (1995) 141-151
21. Jonsson J., Carlsson L., Edlund T., and Edlund H. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371 (1994) 606-609
22. Kim S.K., and Melton D.A. Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 13036-13041
23. Korsgren O., Sandler S., Jansson L., Groth C.G., Hellerstrom C., and Andersson A. Effects of culture conditions on formation and hormone content of fetal porcine isletlike cell clusters. Diabetes 38 Suppl 1 (1989) 209-212
24. Ku H.T., Zhang N., Kubo A., O'Connor R., Mao M., Keller G., and Bromberg J.S. Committing embryonic stem cells to early endocrine pancreas in vitro. Stem Cells 22 (2004) 1205-1217
25. Kubo A., Shinozaki K., Shannon J.M., Kouskoff V., Kennedy M., Woo S., Fehling H.J., and Keller G. Development of definitive endoderm from embryonic stem cells in culture. Development 131 (2004) 1651-1662
26. Lawson K.A., Meneses J.J., and Pedersen R.A. Clonal analysis of epiblast fate during germ layer formation in the mouse embryo. Development 113 (1991) 891-911
27. Lukinius A., and Korsgren O. The transplanted fetal endocrine pancreas undergoes an inherent sequential differentiation similar to that in the native pancreas. An ultrastructural study in the pig-to-mouse model. Diabetes 50 (2001) 962-971
28. Mandel T.E., Collier S., Hoffman L., Pyke K., Carter W.M., and Koulmanda M. Isotransplantation of fetal mouse pancreas in experimental diabetes. Effect of gestational age and organ culture. Lab. Invest. 47 (1982) 477-483
29. Martin M., Gallego-Llamas J., Ribes V., Kedinger M., Niederreither K., Chambon P., Dolle P., and Gradwohl G. Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice. Dev. Biol. 284 (2005) 399-411
30. Matsuura R., Kogo H., Ogaeri T., Miwa T., Kuwahara M., Kanai Y., Nakagawa T., Kuroiwa A., Fujimoto T., and Torihashi S. Crucial transcription factors in endoderm and embryonic gut development are expressed in gut-like structures from mouse ES cells. Stem Cells 24 (2006) 624-630
31. McGrath K.E., Koniski A.D., Maltby K.M., McGann J.K., and Palis J. Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4. Dev. Biol. 213 (1999) 442-456
32. Micallef S.J., Janes M.E., Knezevic K., Davis R.P., Elefanty A.G., and Stanley E.G. Retinoic acid induces Pdx1-positive endoderm in differentiating mouse embryonic stem cells. Diabetes 54 (2005) 301-305
33. Nagy A., Rossant J., Nagy R., Abramow-Newerly W., and Roder J.C. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. U. S. A. 90 (1993) 8424-8428
34. Ng E.S., Azzola L., Sourris K., Robb L., Stanley E.G., and Elefanty A.G. The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells. Development 132 (2005) 873-884
35. Ng E.S., Davis R.P., Azzola L., Stanley E.G., and Elefanty A.G. Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation. Blood 106 (2005) 1601-1603
36. Offield M.F., Jetton T.L., Labosky P.A., Ray M., Stein R.W., Magnuson M.A., Hogan B.L., and Wright C.V. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 122 (1996) 983-995
37. Park C., Afrikanova I., Chung Y.S., Zhang W.J., Arentson E., Fong Gh G., Rosendahl A., and Choi K. A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells. Development 131 (2004) 2749-2762
38. Risau W., Sariola H., Zerwes H.G., Sasse J., Ekblom P., Kemler R., and Doetschman T. Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies. Development 102 (1988) 471-478
39. Shi Y., Hou L., Tang F., Jiang W., Wang P., Ding M., and Deng H. Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid. Stem Cells 23 (2005) 656-662
40. Snow M.H. Autonomous development of parts isolated from primitive-streak-stage mouse embryos. Is development clonal?. J. Embryol. Exp. Morphol. 65 (1981) 269-287 (Suppl)
41. Stafford D., and Prince V.E. Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development. Curr. Biol. 12 (2002) 1215-1220
42. Stafford D., White R.J., Kinkel M.D., Linville A., Schilling T.F., and Prince V.E. Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells. Development 133 (2006) 949-956
43. Sutherland R.M., Mountford J.N., Allison J., Harrison L.C., and Lew A.M. The non-immune RIP-Kb mouse is a useful host for islet transplantation, as the diabetes is spontaneous, mild and predictable. Int. J. Exp. Diabetes Res. 3 (2002) 37-45
44. Tada S., Era T., Furusawa C., Sakurai H., Nishikawa S., Kinoshita M., Nakao K., and Chiba T. Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture. Development 132 (2005) 4363-4374
45. Tam P.P., and Behringer R.R. Mouse gastrulation: the formation of a mammalian body plan. Mech. Dev. 68 (1997) 3-25
46. Tam P.P., Kanai-Azuma M., and Kanai Y. Early endoderm development in vertebrates: lineage differentiation and morphogenetic function. Curr. Opin. Genet. Dev. 13 (2003) 393-400
47. Tam P.P., Loebel D.A., and Tanaka S.S. Building the mouse gastrula: signals, asymmetry and lineages. Curr. Opin. Genet. Dev. 16 (2006) 419-425
48. Tam P.P., Parameswaran M., Kinder S.J., and Weinberger R.P. The allocation of epiblast cells to the embryonic heart and other mesodermal lineages: the role of ingression and tissue movement during gastrulation. Development 124 (1997) 1631-1642
49. Torihashi S. Formation of gut-like structures in vitro from mouse embryonic stem cells. Methods Mol. Biol. 330 (2006) 279-285
50. Wang R., Clark R., and Bautch V.L. Embryonic stem cell-derived cystic embryoid bodies form vascular channels: an in vitro model of blood vessel development. Development 114 (1992) 303-316
51. Wessells N.K., and Cohen J.H. Early pancreas organogenesis: Morphogenesis, tissue interactions, and mass effects. Dev. Biol. 15 (1967) 237-270
52. Wiles M.V., and Johansson B.M. Embryonic stem cell development in a chemically defined medium. Exp. Cell Res. 247 (1999) 241-248
53. Yamada T., and Nakajima Y. Derivation and characterization of gut-like structures from embryonic stem cells. Methods Mol. Biol. 330 (2006) 263-278
54. Yamada T., Yoshikawa M., Takaki M., Torihashi S., Kato Y., Nakajima Y., Ishizaka S., and Tsunoda Y. In vitro functional gut-like organ formation from mouse embryonic stem cells. Stem Cells 20 (2002) 41-49
55. Yasunaga M., Tada S., Torikai-Nishikawa S., Nakano Y., Okada M., Jakt L.M., Nishikawa S., Chiba T., and Era T. Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells. Nat. Biotechnol. 23 (2005) 1542-1550