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Volumn 67, Issue 23, 2007, Pages 11411-11418

Identification of genes required for protection from doxorubicin by a genome-wide screen in Saccharomyces cerevisiae

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; ADENYLATE KINASE 1; CAMPTOTHECIN; CARRIER PROTEIN; CELL PROTEIN; CISPLATIN; COPPER ZINC SUPEROXIDE DISMUTASE; DAUNORUBICIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE 3; DOXORUBICIN; HYDROXYUREA; MRE11 PROTEIN; NUCLEIC ACID BINDING PROTEIN; PHOSPHOGLUCONATE DEHYDROGENASE; PROTEIN BEM1; PROTEIN BEM4; PROTEIN RAD55; PROTEIN RAD57; PROTEIN RPL37A; PROTEIN SAC7; PROTEIN SER1; PROTEIN SER2; RAD50 PROTEIN; RAD51 PROTEIN; RAD52 PROTEIN; RIBOSOME PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MAC1; TRANSCRIPTION FACTOR UAF30; UNCLASSIFIED DRUG;

EID: 37049036370     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-2399     Document Type: Article
Times cited : (35)

References (46)
  • 1
    • 0014603427 scopus 로고
    • Adriamycin, 14-hydroxydaunomycin, a new antitumor antibiotic from S. peucetius var. caesius
    • Arcamone F, Cassinelli G, Fantini G, et al. Adriamycin, 14-hydroxydaunomycin, a new antitumor antibiotic from S. peucetius var. caesius. Biotechnol Bioeng 1969;11:1101-10.
    • (1969) Biotechnol Bioeng , vol.11 , pp. 1101-1110
    • Arcamone, F.1    Cassinelli, G.2    Fantini, G.3
  • 2
    • 0026714331 scopus 로고
    • The anthracyclines: Will we ever find a better doxorubicin?
    • Weiss RB. The anthracyclines: will we ever find a better doxorubicin? Semin Oncol 1992;19:670-86.
    • (1992) Semin Oncol , vol.19 , pp. 670-686
    • Weiss, R.B.1
  • 3
    • 0038783150 scopus 로고    scopus 로고
    • Epirubicin versus doxorubicin: Which is the anthracycline of choice for the treatment of breast cancer?
    • Kaklamani VG, Gradishar WJ. Epirubicin versus doxorubicin: which is the anthracycline of choice for the treatment of breast cancer? Clin Breast Cancer 2003;4 Suppl 1:S26-33.
    • (2003) Clin Breast Cancer , vol.4 , Issue.SUPPL. 1
    • Kaklamani, V.G.1    Gradishar, W.J.2
  • 4
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
    • Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 2004;56:185-229.
    • (2004) Pharmacol Rev , vol.56 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 5
    • 0032563825 scopus 로고    scopus 로고
    • Doxorubicin-induced cardiomyopathy
    • Singal PK, Iliskovic N. Doxorubicin-induced cardiomyopathy. N Engl J Med 1998;339:900-5.
    • (1998) N Engl J Med , vol.339 , pp. 900-905
    • Singal, P.K.1    Iliskovic, N.2
  • 6
    • 18744377282 scopus 로고    scopus 로고
    • Dexrazoxane: A review of its use for cardioprotection during anthracycline chemotherapy
    • Cvetkovic RS, Scott LJ. Dexrazoxane: a review of its use for cardioprotection during anthracycline chemotherapy. Drugs 2005;65:1005-24.
    • (2005) Drugs , vol.65 , pp. 1005-1024
    • Cvetkovic, R.S.1    Scott, L.J.2
  • 7
    • 0023630851 scopus 로고
    • The major metabolite of doxorubicin is a potent inhibitor of membrane-associated ion pumps. A correlative study of cardiac muscle with isolated membrane fractions
    • Boucek RJ, Jr., Olson RD, Brenner DE, Ogunbunmi EM, Inui M, Fleischer S. The major metabolite of doxorubicin is a potent inhibitor of membrane-associated ion pumps. A correlative study of cardiac muscle with isolated membrane fractions. J Biol Chem 1987;262:15851-6.
    • (1987) J Biol Chem , vol.262 , pp. 15851-15856
    • Boucek Jr., R.J.1    Olson, R.D.2    Brenner, D.E.3    Ogunbunmi, E.M.4    Inui, M.5    Fleischer, S.6
  • 8
    • 0027977771 scopus 로고
    • Anthracycline antibiotics in cancer therapy. Focus on drug resistance
    • Booser DJ, Hortobagyi GN. Anthracycline antibiotics in cancer therapy. Focus on drug resistance. Drugs 1994;47:223-58.
    • (1994) Drugs , vol.47 , pp. 223-258
    • Booser, D.J.1    Hortobagyi, G.N.2
  • 9
    • 0031754926 scopus 로고    scopus 로고
    • Mechanisms of cellular anthracycline resistance in childhood acute leukemia
    • Den Boer ML, Pieters R, Veerman AJ. Mechanisms of cellular anthracycline resistance in childhood acute leukemia. Leukemia 1998;12:1657-70.
    • (1998) Leukemia , vol.12 , pp. 1657-1670
    • Den Boer, M.L.1    Pieters, R.2    Veerman, A.J.3
  • 10
    • 18544396501 scopus 로고    scopus 로고
    • Gianni L. Anthracycline resistance: the problem and its current definition. Semin Oncol 1997;24:S10-1-S-7.
    • Gianni L. Anthracycline resistance: the problem and its current definition. Semin Oncol 1997;24:S10-1-S-7.
  • 11
    • 0030846198 scopus 로고    scopus 로고
    • Sequential dose-dense adjuvant therapy with doxorubicin, paclitaxel, and cyclophosphamide
    • Hudis C. Sequential dose-dense adjuvant therapy with doxorubicin, paclitaxel, and cyclophosphamide. Oncology (Huntingt) 1997;11:15-8.
    • (1997) Oncology (Huntingt) , vol.11 , pp. 15-18
    • Hudis, C.1
  • 12
    • 0027971717 scopus 로고
    • Combination paclitaxel (Taxol) and doxorubicin therapy for metastatic breast cancer
    • O'Shaughnessy JA, Fisherman JS, Cowan KH. Combination paclitaxel (Taxol) and doxorubicin therapy for metastatic breast cancer. Semin Oncol 1994;21:19-23.
    • (1994) Semin Oncol , vol.21 , pp. 19-23
    • O'Shaughnessy, J.A.1    Fisherman, J.S.2    Cowan, K.H.3
  • 13
    • 33745446513 scopus 로고    scopus 로고
    • Optimal therapy for platinum-resistant recurrent ovarian cancer: Doxorubicin, gemcitabine or topotecan?
    • Pectasides D, Psyrri A, Pectasides M, Economopoulos T. Optimal therapy for platinum-resistant recurrent ovarian cancer: doxorubicin, gemcitabine or topotecan? Expert Opin Pharmacother 2006;7:975-87.
    • (2006) Expert Opin Pharmacother , vol.7 , pp. 975-987
    • Pectasides, D.1    Psyrri, A.2    Pectasides, M.3    Economopoulos, T.4
  • 14
    • 0034823009 scopus 로고    scopus 로고
    • Doxorubicin and taxane combination regimens for metastatic breast cancer: Focus on cardiac effects
    • Valero V, Perez E, Dieras V. Doxorubicin and taxane combination regimens for metastatic breast cancer: focus on cardiac effects. Semin Oncol 2001;28:15-23.
    • (2001) Semin Oncol , vol.28 , pp. 15-23
    • Valero, V.1    Perez, E.2    Dieras, V.3
  • 15
    • 0032933747 scopus 로고    scopus 로고
    • Dependence on RAD52 and RAD1 for anticancer drug resistance mediated by inactivation of mismatch repair genes
    • Durant ST, Morris MM, Illand M, et al. Dependence on RAD52 and RAD1 for anticancer drug resistance mediated by inactivation of mismatch repair genes. Curr Biol 1999;9:51-4.
    • (1999) Curr Biol , vol.9 , pp. 51-54
    • Durant, S.T.1    Morris, M.M.2    Illand, M.3
  • 17
    • 0033529707 scopus 로고    scopus 로고
    • Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis
    • Winzeler EA, Shoemaker DD, Astromoff A, et al. Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 1999;285:901-6.
    • (1999) Science , vol.285 , pp. 901-906
    • Winzeler, E.A.1    Shoemaker, D.D.2    Astromoff, A.3
  • 19
    • 21344433235 scopus 로고    scopus 로고
    • Genomewide screen identifies genes whose inactivation confer resistance to cisplatin in Saccharomyces cerevisiae
    • Huang RY, Eddy M, Vujcic M, Kowalski D. Genomewide screen identifies genes whose inactivation confer resistance to cisplatin in Saccharomyces cerevisiae. Cancer Res 2005;65:5890-7.
    • (2005) Cancer Res , vol.65 , pp. 5890-5897
    • Huang, R.Y.1    Eddy, M.2    Vujcic, M.3    Kowalski, D.4
  • 20
    • 0028331722 scopus 로고
    • Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae
    • Alani E, Reenan RA, Kolodner RD. Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. Genetics 1994;137:19-39.
    • (1994) Genetics , vol.137 , pp. 19-39
    • Alani, E.1    Reenan, R.A.2    Kolodner, R.D.3
  • 21
    • 0031442653 scopus 로고    scopus 로고
    • A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair
    • Tishkoff DX, Filosi N, Gaida GM, Kolodner RD. A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair. Cell 1997;88:253-63.
    • (1997) Cell , vol.88 , pp. 253-263
    • Tishkoff, D.X.1    Filosi, N.2    Gaida, G.M.3    Kolodner, R.D.4
  • 22
    • 33846676764 scopus 로고    scopus 로고
    • Small ubiquitin-related modifier pathway is a major determinant of doxorubicin cytotoxicity in Saccharomyces cerevisiae
    • Huang RY, Kowalski D, Minderman H, Gandhi N, Johnson ES. Small ubiquitin-related modifier pathway is a major determinant of doxorubicin cytotoxicity in Saccharomyces cerevisiae. Cancer Res 2007;67:765-72.
    • (2007) Cancer Res , vol.67 , pp. 765-772
    • Huang, R.Y.1    Kowalski, D.2    Minderman, H.3    Gandhi, N.4    Johnson, E.S.5
  • 23
    • 28844444558 scopus 로고    scopus 로고
    • Multifaceted role of the Saccharomyces cerevisiae Srs2 helicase in homologous recombination regulation
    • Macris MA, Sung P. Multifaceted role of the Saccharomyces cerevisiae Srs2 helicase in homologous recombination regulation. Biochem Soc Trans 2005;33:1447-50.
    • (2005) Biochem Soc Trans , vol.33 , pp. 1447-1450
    • Macris, M.A.1    Sung, P.2
  • 24
    • 32644454570 scopus 로고    scopus 로고
    • Sumoylation of PCNA: Wrestling with recombination at stalled replication forks
    • Watts FZ. Sumoylation of PCNA: wrestling with recombination at stalled replication forks. DNA Repair (Amst) 2006;5:399-403.
    • (2006) DNA Repair (Amst) , vol.5 , pp. 399-403
    • Watts, F.Z.1
  • 25
    • 1042290351 scopus 로고    scopus 로고
    • The SWI/SNF complex-chromatin and cancer
    • Roberts CW, Orkin SH. The SWI/SNF complex-chromatin and cancer. Nat Rev Cancer 2004;4:133-42.
    • (2004) Nat Rev Cancer , vol.4 , pp. 133-142
    • Roberts, C.W.1    Orkin, S.H.2
  • 26
    • 0036889144 scopus 로고    scopus 로고
    • HTL1 encodes a novel factor that interacts with the RSC chromatin remodeling complex in Saccharomyces cerevisiae
    • Romeo MJ, Angus-Hill ML, Sobering AK, Kamada Y, Cairns BR, Levin DE. HTL1 encodes a novel factor that interacts with the RSC chromatin remodeling complex in Saccharomyces cerevisiae. Mol Cell Biol 2002;22:8165-74.
    • (2002) Mol Cell Biol , vol.22 , pp. 8165-8174
    • Romeo, M.J.1    Angus-Hill, M.L.2    Sobering, A.K.3    Kamada, Y.4    Cairns, B.R.5    Levin, D.E.6
  • 27
    • 0042671282 scopus 로고    scopus 로고
    • Involvement of actin-related proteins in ATP-dependent chromatin remodeling
    • Shen X, Ranallo R, Choi E, Wu C. Involvement of actin-related proteins in ATP-dependent chromatin remodeling. Mol Cell 2003;12:147-55.
    • (2003) Mol Cell , vol.12 , pp. 147-155
    • Shen, X.1    Ranallo, R.2    Choi, E.3    Wu, C.4
  • 28
    • 0030977168 scopus 로고    scopus 로고
    • ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3
    • Horiuchi J, Silverman N, Pina B, Marcus GA, Guarente L. ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3. Mol Cell Biol 1997;17:3220-8.
    • (1997) Mol Cell Biol , vol.17 , pp. 3220-3228
    • Horiuchi, J.1    Silverman, N.2    Pina, B.3    Marcus, G.A.4    Guarente, L.5
  • 29
    • 0035881963 scopus 로고    scopus 로고
    • Transcription of chromosomal rRNA genes by both RNA polymerase I and II in yeast uaf30 mutants lacking the 30 kDa subunit of transcription factor UAF
    • Siddiqi IN, Dodd JA, Vu L, et al. Transcription of chromosomal rRNA genes by both RNA polymerase I and II in yeast uaf30 mutants lacking the 30 kDa subunit of transcription factor UAF. EMBO J 2001;20:4512-21.
    • (2001) EMBO J , vol.20 , pp. 4512-4521
    • Siddiqi, I.N.1    Dodd, J.A.2    Vu, L.3
  • 31
    • 0037423930 scopus 로고    scopus 로고
    • Conserved histone variant H2A Z protects euchromatin from the ectopic spread of silent heterochromatin
    • Meneghini MD, Wu M, Madhani HD. Conserved histone variant H2A Z protects euchromatin from the ectopic spread of silent heterochromatin. Cell 2003;112:725-36.
    • (2003) Cell , vol.112 , pp. 725-736
    • Meneghini, M.D.1    Wu, M.2    Madhani, H.D.3
  • 32
    • 33846818840 scopus 로고    scopus 로고
    • Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56
    • Driscoll R, Hudson A, Jackson SP. Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56. Science 2007;315:649-52.
    • (2007) Science , vol.315 , pp. 649-652
    • Driscoll, R.1    Hudson, A.2    Jackson, S.P.3
  • 33
    • 4344590764 scopus 로고    scopus 로고
    • The J-protein family: Modulating protein assembly, disassembly and translocation
    • Walsh P, Bursac D, Law YC, Cyr D, Lithgow T. The J-protein family: modulating protein assembly, disassembly and translocation. EMBO Rep 2004;5:567-71.
    • (2004) EMBO Rep , vol.5 , pp. 567-571
    • Walsh, P.1    Bursac, D.2    Law, Y.C.3    Cyr, D.4    Lithgow, T.5
  • 34
    • 0035958547 scopus 로고    scopus 로고
    • Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI(+)] prion
    • Osherovich LZ, Weissman JS. Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI(+)] prion. Cell 2001;106:183-94.
    • (2001) Cell , vol.106 , pp. 183-194
    • Osherovich, L.Z.1    Weissman, J.S.2
  • 35
    • 13644261913 scopus 로고    scopus 로고
    • Genome-wide survey of non-essential genes required for slowed DNA synthesis-induced filamentous growth in yeast
    • Kang CM, Jiang YW. Genome-wide survey of non-essential genes required for slowed DNA synthesis-induced filamentous growth in yeast. Yeast 2005;22:79-90.
    • (2005) Yeast , vol.22 , pp. 79-90
    • Kang, C.M.1    Jiang, Y.W.2
  • 36
    • 0028044149 scopus 로고
    • Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches
    • Chi NW, Kolodner RD. Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches. J Biol Chem 1994;269:29984-92.
    • (1994) J Biol Chem , vol.269 , pp. 29984-29992
    • Chi, N.W.1    Kolodner, R.D.2
  • 37
    • 0031921170 scopus 로고    scopus 로고
    • Mitochondrial inheritance is delayed in Saccharomyces cerevisiae cells lacking the serine/threonine phosphatase PTC1
    • Roeder AD, Hermann GJ, Keegan BR, Thatcher SA, Shaw JM. Mitochondrial inheritance is delayed in Saccharomyces cerevisiae cells lacking the serine/threonine phosphatase PTC1. Mol Biol Cell 1998;9:917-30.
    • (1998) Mol Biol Cell , vol.9 , pp. 917-930
    • Roeder, A.D.1    Hermann, G.J.2    Keegan, B.R.3    Thatcher, S.A.4    Shaw, J.M.5
  • 39
    • 0019390734 scopus 로고
    • DNA double-stranded breaks in mammalian cells after exposure to intercalating agents
    • Ross WE, Bradley MO. DNA double-stranded breaks in mammalian cells after exposure to intercalating agents. Biochim Biophys Acta 1981;654:129-34.
    • (1981) Biochim Biophys Acta , vol.654 , pp. 129-134
    • Ross, W.E.1    Bradley, M.O.2
  • 40
    • 0021151237 scopus 로고
    • Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II
    • Tewey KM, Rowe TC, Yang L, Halligan BD, Liu LF. Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II. Science 1984;226:466-8.
    • (1984) Science , vol.226 , pp. 466-468
    • Tewey, K.M.1    Rowe, T.C.2    Yang, L.3    Halligan, B.D.4    Liu, L.F.5
  • 41
    • 33747041690 scopus 로고    scopus 로고
    • Pharmacological induction of Hsp70 protects apoptosis-prone cells from doxorubicin: Comparison with caspase-inhibitor-and cycle-arrest-mediated cytoprotection
    • Demidenko ZN, Vivo C, Halicka HD, et al. Pharmacological induction of Hsp70 protects apoptosis-prone cells from doxorubicin: comparison with caspase-inhibitor-and cycle-arrest-mediated cytoprotection. Cell Death Differ 2006;13:1434-41.
    • (2006) Cell Death Differ , vol.13 , pp. 1434-1441
    • Demidenko, Z.N.1    Vivo, C.2    Halicka, H.D.3
  • 44
    • 3142557997 scopus 로고    scopus 로고
    • Activation of pleiotropic drug resistance by the J-protein and Hsp70-related proteins, Zuo1 and Ssz1
    • Eisenman HC, Craig EA. Activation of pleiotropic drug resistance by the J-protein and Hsp70-related proteins, Zuo1 and Ssz1. Mol Microbiol 2004;53:335-44.
    • (2004) Mol Microbiol , vol.53 , pp. 335-344
    • Eisenman, H.C.1    Craig, E.A.2
  • 45
    • 6344249087 scopus 로고    scopus 로고
    • FKBP12 controls aspartate pathway flux in Saccharomyces cerevisiae to prevent toxic intermediate accumulation
    • Arevalo-Rodriguez M, Pan X, Boeke JD, Heitman J. FKBP12 controls aspartate pathway flux in Saccharomyces cerevisiae to prevent toxic intermediate accumulation. Eukaryot Cell 2004;3:1287-96.
    • (2004) Eukaryot Cell , vol.3 , pp. 1287-1296
    • Arevalo-Rodriguez, M.1    Pan, X.2    Boeke, J.D.3    Heitman, J.4
  • 46
    • 0036667351 scopus 로고    scopus 로고
    • Thresholds of carcinogenicity of flavors
    • Waddell WJ. Thresholds of carcinogenicity of flavors. Toxicol Sci 2002;68:275-9.
    • (2002) Toxicol Sci , vol.68 , pp. 275-279
    • Waddell, W.J.1


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