Direct Comparison of Biologically Optimized Spread-out Bragg Peaks for Protons and Carbon Ions

International Journal of Radiation Oncology Biology Physics

Volumn 70, Issue 1, 2008, Pages 262-266

  Wilkens, Jan J ^a   Oelfke, Uwe ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Carbon ions; Optimization; Protons; Relative biologic effectiveness; Spread out Bragg peak

Indexed keywords

CARBON; DOSIMETRY; OPTIMIZATION; PROTONS; TISSUE;

CARBON IONS; RELATIVE BIOLOGIC EFFECTIVENESS; SPREAD OUT BRAGG PEAK;

RADIOTHERAPY;

CARBON;

ARTICLE; BEAM THERAPY; BIOLOGICAL MODEL; CALCULATION; ION THERAPY; LINEAR ENERGY TRANSFER; PREDICTION; PRIORITY JOURNAL; PROTON RADIATION; RADIATION DOSE; RADIATION DOSE DISTRIBUTION; RADIATION PHYSICS;

CARBON; LINEAR ENERGY TRANSFER; LINEAR MODELS; PROTONS; RELATIVE BIOLOGICAL EFFECTIVENESS;

EID: 37049036347     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2007.08.029     Document Type: Article

References (14)

1. Oelfke U., and Bortfeld T. Optimization of physical dose distributions with hadron beams: Comparing photon IMRT with IMPT. Technol Cancer Res Treat 2 (2003) 401-412
2. Bortfeld T. An analytical approximation of the Bragg curve for therapeutic proton beams. Med Phys 24 (1997) 2024-2033
3. Weber U., and Kraft G. Design and construction of a ripple filter for a smoothed depth dose distribution in conformal particle therapy. Phys Med Biol 44 (1999) 2765-2775
4. Krämer M., Jäkel O., Haberer T., et al. Treatment planning for heavy-ion radiotherapy: Physical beam model and dose optimization. Phys Med Biol 45 (2000) 3299-3317
5. Wilkens J.J., and Oelfke U. Fast multifield optimization of the biological effect in ion therapy. Phys Med Biol 51 (2006) 3127-3140
6. Krämer M., and Scholz M. Treatment planning for heavy-ion radiotherapy: Calculation and optimization of biologically effective dose. Phys Med Biol 45 (2000) 3319-3330
7. Schulz-Ertner D., Nikoghosyan A., Thilmann C., et al. Carbon ion radiotherapy for chordomas and low-grade chondrosarcomas of the skull base. Strahlenther Onkol 9 (2003) 598-605
8. Kanai T., Matsufuji N., Miyamoto T., et al. Examination of GyE system for HIMAC carbon therapy. Int J Radiat Oncol Biol Phys 64 (2006) 650-656
9. Wilkens J.J., and Oelfke U. A phenomenological model for the relative biological effectiveness in therapeutic proton beams. Phys Med Biol 49 (2004) 2811-2825
10. Tilly N., Johansson J., Isacsson U., et al. The influence of RBE variations in a clinical proton treatment plan for a hypopharynx cancer. Phys Med Biol 50 (2005) 2765-2777
11. Krämer M. Treatment-planning for heavy-ion radiotherapy: Biological optimization of multiple beam ports. J Radiat Res 42 (2001) 39-46
12. Karger C.P., Peschke P., Sanchez-Brandelik R., et al. Radiation tolerance of the rat spinal cord after 6 and 18 fractions of photons and carbon ions: Experimental results and clinical implications. Int J Radiat Oncol Biol Phys 66 (2006) 1488-1497
13. Elsässer T., and Scholz M. Cluster effects within the local effect model. Rad Res 167 (2007) 319-329
14. Scholz M. Calculation of tumor control probability for non small-cell lung cancer after carbon ion therapy: An application of the local effect model [Abstract]. Presented at the 46th meeting of the Particle Therapy Co-Operative Group (PTCOG), Zibo, China, May 21-23, 2007.