메뉴 건너뛰기




Volumn 66, Issue 5, 2006, Pages 1488-1497

Radiation tolerance of the rat spinal cord after 6 and 18 fractions of photons and carbon ions: Experimental results and clinical implications

Author keywords

carbon ions; Charged particle radiotherapy; radiation tolerance; rat spinal cord; relative biologic effectiveness

Indexed keywords

DATA REDUCTION; FRACTIONATION; IONS; MATHEMATICAL MODELS; PHOTONS;

EID: 33751182861     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2006.08.045     Document Type: Article
Times cited : (85)

References (50)
  • 1
    • 0347596708 scopus 로고    scopus 로고
    • Radiation tolerance of the rat spinal cord after single and split doses of photons and carbon ions
    • Debus J., Scholz M., Haberer T., et al. Radiation tolerance of the rat spinal cord after single and split doses of photons and carbon ions. Radiat Res 160 (2003) 536-542
    • (2003) Radiat Res , vol.160 , pp. 536-542
    • Debus, J.1    Scholz, M.2    Haberer, T.3
  • 3
    • 0034506342 scopus 로고    scopus 로고
    • Tumortherapy with heavy charged particles
    • Kraft G. Tumortherapy with heavy charged particles. Prog Part Nucl Phys 45 (2000) S473-S544
    • (2000) Prog Part Nucl Phys , vol.45
    • Kraft, G.1
  • 4
    • 0027963257 scopus 로고
    • Experience in charged particle irradiation of tumors of the skull base: 1977-1992
    • Castro J.R., Linstadt D.E., Bahary J.-P., et al. Experience in charged particle irradiation of tumors of the skull base: 1977-1992. Int J Radiat Oncol Biol Phys 29 (1994) 647-655
    • (1994) Int J Radiat Oncol Biol Phys , vol.29 , pp. 647-655
    • Castro, J.R.1    Linstadt, D.E.2    Bahary, J.-P.3
  • 5
    • 0028970260 scopus 로고
    • Results of heavy ion radiotherapy
    • Castro J.R. Results of heavy ion radiotherapy. Radiat Environ Biophys 34 (1995) 45-48
    • (1995) Radiat Environ Biophys , vol.34 , pp. 45-48
    • Castro, J.R.1
  • 6
    • 21444434428 scopus 로고    scopus 로고
    • Status of the clinical work at Hyogo
    • Hishikawa Y., Oda Y., Mayahara H., et al. Status of the clinical work at Hyogo. Radiother Oncol 73 Suppl. 2 (2004) S38-S40
    • (2004) Radiother Oncol , vol.73 , Issue.SUPPL. 2
    • Hishikawa, Y.1    Oda, Y.2    Mayahara, H.3
  • 7
    • 0033011695 scopus 로고    scopus 로고
    • Biophysical characteristics of HIMAC clinical irradiation system for heavy-ion radiation therapy
    • Kanai T., Endo M., Minohara S., et al. Biophysical characteristics of HIMAC clinical irradiation system for heavy-ion radiation therapy. Int J Radiat Oncol Biol Phys 44 (1999) 201-210
    • (1999) Int J Radiat Oncol Biol Phys , vol.44 , pp. 201-210
    • Kanai, T.1    Endo, M.2    Minohara, S.3
  • 8
    • 21444447811 scopus 로고    scopus 로고
    • Overview of clinical experiences on carbon ion radiotherapy at NIRS
    • Tsujii H., Mizoe J.E., Kamada T., et al. Overview of clinical experiences on carbon ion radiotherapy at NIRS. Radiother Oncol 73 Suppl. 2 (2004) S41-S49
    • (2004) Radiother Oncol , vol.73 , Issue.SUPPL. 2
    • Tsujii, H.1    Mizoe, J.E.2    Kamada, T.3
  • 9
    • 0034316964 scopus 로고    scopus 로고
    • Tumortherapy with ion beams
    • Kraft G. Tumortherapy with ion beams. Nucl Instrum Meth A454 (2000) 1-10
    • (2000) Nucl Instrum Meth , vol.A454 , pp. 1-10
    • Kraft, G.1
  • 10
    • 0038300484 scopus 로고    scopus 로고
    • Feasibility and toxicity of combined photon and carbon ion radiotherapy for locally advanced adenoid cystic carcinomas
    • Schulz-Ertner D., Nikoghosyan A., Jäkel O., et al. Feasibility and toxicity of combined photon and carbon ion radiotherapy for locally advanced adenoid cystic carcinomas. Int J Radiat Oncol Biol Phys 56 (2003) 391-398
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 391-398
    • Schulz-Ertner, D.1    Nikoghosyan, A.2    Jäkel, O.3
  • 11
    • 0042825228 scopus 로고    scopus 로고
    • Carbon ion radiotherapy for chordomas and low-grade chondrosarcomas of the skull base: Results in 67 patients
    • Schulz-Ertner D., Nikoghosyan A., Thilmann C., et al. Carbon ion radiotherapy for chordomas and low-grade chondrosarcomas of the skull base: Results in 67 patients. Strahlenther Onkol 179 (2003) 598-605
    • (2003) Strahlenther Onkol , vol.179 , pp. 598-605
    • Schulz-Ertner, D.1    Nikoghosyan, A.2    Thilmann, C.3
  • 12
    • 21444442414 scopus 로고    scopus 로고
    • Carbon ion radiation therapy for chordomas and low grade chondrosarcomas-current status of the clinical trials at GSI
    • Schulz-Ertner D., Nikoghosyan A., Didinger B., et al. Carbon ion radiation therapy for chordomas and low grade chondrosarcomas-current status of the clinical trials at GSI. Radiother Oncol 73 Suppl. 2 (2004) S53-S56
    • (2004) Radiother Oncol , vol.73 , Issue.SUPPL. 2
    • Schulz-Ertner, D.1    Nikoghosyan, A.2    Didinger, B.3
  • 14
    • 22244457629 scopus 로고    scopus 로고
    • Therapy strategies for locally advanced adenoid cystic carcinomas using modern radiation therapy techniques
    • Schulz-Ertner D., Nikoghosyan A., Didinger B., et al. Therapy strategies for locally advanced adenoid cystic carcinomas using modern radiation therapy techniques. Cancer 104 (2005) 338-344
    • (2005) Cancer , vol.104 , pp. 338-344
    • Schulz-Ertner, D.1    Nikoghosyan, A.2    Didinger, B.3
  • 15
    • 21444434583 scopus 로고    scopus 로고
    • The Heidelberg ion therapy center
    • Haberer T., Debus J., Eickhoff H., et al. The Heidelberg ion therapy center. Radiother Oncol 73 Suppl. 2 (2004) 186-190
    • (2004) Radiother Oncol , vol.73 , Issue.SUPPL. 2 , pp. 186-190
    • Haberer, T.1    Debus, J.2    Eickhoff, H.3
  • 16
    • 1842511739 scopus 로고    scopus 로고
    • Die Konzeption der Heidelberger Ionentherapieanlage HICAT
    • Heeg P., Eickhoff H., Haberer T.H., et al. Die Konzeption der Heidelberger Ionentherapieanlage HICAT. Z Med Phys 14 (2004) 17-24
    • (2004) Z Med Phys , vol.14 , pp. 17-24
    • Heeg, P.1    Eickhoff, H.2    Haberer, T.H.3
  • 17
    • 33751161262 scopus 로고    scopus 로고
    • Sisterson J. (Ed), Harvard Cyclotron Laboratory, Harvard University, Boston
    • In: Sisterson J. (Ed). Particles Newsletter 36 (2005), Harvard Cyclotron Laboratory, Harvard University, Boston
    • (2005) Particles Newsletter 36
  • 18
    • 0027609090 scopus 로고
    • Magnetic scanning system for heavy ion therapy
    • Haberer T., Becher W., Schardt D., et al. Magnetic scanning system for heavy ion therapy. Nucl Instrum Meth A330 (1993) 296-305
    • (1993) Nucl Instrum Meth , vol.A330 , pp. 296-305
    • Haberer, T.1    Becher, W.2    Schardt, D.3
  • 19
    • 24944578548 scopus 로고    scopus 로고
    • Results of spot-scanning proton radiation therapy for chordoma and chondrosarcoma of the skull base: The Paul-Scherrer Institut experience
    • Weber D.C., Rutz H.P., Pedroni E.S., et al. Results of spot-scanning proton radiation therapy for chordoma and chondrosarcoma of the skull base: The Paul-Scherrer Institut experience. Int J Radiat Oncol Biol Phys 63 (2005) 401-409
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 401-409
    • Weber, D.C.1    Rutz, H.P.2    Pedroni, E.S.3
  • 20
    • 0344183081 scopus 로고    scopus 로고
    • Initial experience of using an active beam delivery technique at PSI
    • Pedroni E., Böhringer T., Coray A., et al. Initial experience of using an active beam delivery technique at PSI. Strahlenther Onkol 175 Suppl. II (1999) 18-20
    • (1999) Strahlenther Onkol , vol.175 , Issue.SUPPL. II , pp. 18-20
    • Pedroni, E.1    Böhringer, T.2    Coray, A.3
  • 21
    • 0030934588 scopus 로고    scopus 로고
    • Computation of cell survival in heavy ion beams for therapy. The model and its approximation
    • Scholz M., Kellerer A.M., Kraft-Weyrather W., et al. Computation of cell survival in heavy ion beams for therapy. The model and its approximation. Radiat Environ Biophys 36 (1997) 59-66
    • (1997) Radiat Environ Biophys , vol.36 , pp. 59-66
    • Scholz, M.1    Kellerer, A.M.2    Kraft-Weyrather, W.3
  • 22
    • 0028345375 scopus 로고
    • Calculation of heavy ion inactivation probabilities based on track structure, X ray sensitivity and target size
    • Scholz M., and Kraft G. Calculation of heavy ion inactivation probabilities based on track structure, X ray sensitivity and target size. Radiat Prot Dosim 52 (1994) 29-33
    • (1994) Radiat Prot Dosim , vol.52 , pp. 29-33
    • Scholz, M.1    Kraft, G.2
  • 23
    • 0033773556 scopus 로고    scopus 로고
    • Treatment planning for heavy-ion radiotherapy: Physical beam model and dose optimization
    • Krämer M., Jäkel O., Haberer T., et al. Treatment planning for heavy-ion radiotherapy: Physical beam model and dose optimization. Phys Med Biol 45 (2000) 3299-3317
    • (2000) Phys Med Biol , vol.45 , pp. 3299-3317
    • Krämer, M.1    Jäkel, O.2    Haberer, T.3
  • 24
    • 0033747685 scopus 로고    scopus 로고
    • Treatment planning for heavy-ion radiotherapy: Calculation and optimization of biologically effective dose
    • Krämer M., and Scholz M. Treatment planning for heavy-ion radiotherapy: Calculation and optimization of biologically effective dose. Phys Med Biol 45 (2000) 3319-3330
    • (2000) Phys Med Biol , vol.45 , pp. 3319-3330
    • Krämer, M.1    Scholz, M.2
  • 25
    • 0028231628 scopus 로고
    • Radiation response of the rat cervical spinal cord after irradiation at different ages: Tolerance, latency and pathology
    • Ruifrok A.C., Stephens L.C., and van der Kogel A.J. Radiation response of the rat cervical spinal cord after irradiation at different ages: Tolerance, latency and pathology. Int J Radiat Oncol Biol Phys 29 (1994) 73-79
    • (1994) Int J Radiat Oncol Biol Phys , vol.29 , pp. 73-79
    • Ruifrok, A.C.1    Stephens, L.C.2    van der Kogel, A.J.3
  • 26
    • 33751167043 scopus 로고    scopus 로고
    • StatSoft, Inc. (2004). STATISTICA für Windows [Software-System für Datenanalyse] Version 6. www.statsoft.com.
  • 27
    • 45849146096 scopus 로고
    • Brief summary of radiobiological principles in fractionated radiotherapy
    • Fowler J.F. Brief summary of radiobiological principles in fractionated radiotherapy. Sem Radiat Oncol 2 (1992) 16-21
    • (1992) Sem Radiat Oncol , vol.2 , pp. 16-21
    • Fowler, J.F.1
  • 28
    • 0024358259 scopus 로고
    • The linear-quadratic formula and progress in fractionated radiotherapy
    • Fowler J.F. The linear-quadratic formula and progress in fractionated radiotherapy. Br J Radiol 62 (1989) 679-694
    • (1989) Br J Radiol , vol.62 , pp. 679-694
    • Fowler, J.F.1
  • 29
    • 0022506227 scopus 로고
    • Direct analysis of quantal radiation response data
    • Thames H.D., Rozell M.E., Tucker S.L., et al. Direct analysis of quantal radiation response data. Int J Radiat Biol 49 (1986) 999-1009
    • (1986) Int J Radiat Biol , vol.49 , pp. 999-1009
    • Thames, H.D.1    Rozell, M.E.2    Tucker, S.L.3
  • 30
    • 0025051449 scopus 로고
    • Radiation myelopathy in primates treated with conventional fractionation
    • Schultheiss T.E., Stephens L.C., Jiang G.-L., et al. Radiation myelopathy in primates treated with conventional fractionation. Int J Radiat Oncol Biol Phys 19 (1990) 935-940
    • (1990) Int J Radiat Oncol Biol Phys , vol.19 , pp. 935-940
    • Schultheiss, T.E.1    Stephens, L.C.2    Jiang, G.-L.3
  • 31
    • 0026577486 scopus 로고
    • Neutron RBE for primate spinal cord treated with clinical regimes
    • Schultheiss T.E., Stephens L.C., Ang K.K., et al. Neutron RBE for primate spinal cord treated with clinical regimes. Radiat Res 129 (1992) 212-217
    • (1992) Radiat Res , vol.129 , pp. 212-217
    • Schultheiss, T.E.1    Stephens, L.C.2    Ang, K.K.3
  • 33
    • 0023929835 scopus 로고
    • The use of the D versus dD plot to estimate the α/β ratio from iso-effect radiation damage data
    • de Boer R.W. The use of the D versus dD plot to estimate the α/β ratio from iso-effect radiation damage data. Radiother Oncol 11 (1988) 361-367
    • (1988) Radiother Oncol , vol.11 , pp. 361-367
    • de Boer, R.W.1
  • 34
    • 0030707831 scopus 로고    scopus 로고
    • Brainstem tolerance to conformal radiotherapy of skull base tumors
    • Debus J., Hug E.B., Liebsch N.J., et al. Brainstem tolerance to conformal radiotherapy of skull base tumors. Int J Radiat Oncol Biol Phys 39 (1997) 967-975
    • (1997) Int J Radiat Oncol Biol Phys , vol.39 , pp. 967-975
    • Debus, J.1    Hug, E.B.2    Liebsch, N.J.3
  • 35
    • 0026094259 scopus 로고
    • Incidence of radiation myelitis of the cervical spinal cord at doses of 5500 cGy or greater
    • Jeremic B., Djuric L., and Mijatovic L. Incidence of radiation myelitis of the cervical spinal cord at doses of 5500 cGy or greater. Cancer 68 (1991) 2138-2141
    • (1991) Cancer , vol.68 , pp. 2138-2141
    • Jeremic, B.1    Djuric, L.2    Mijatovic, L.3
  • 36
    • 0017115046 scopus 로고
    • The effect of multiple small doses of X rays on skin reactions in the mouse and a basic interpretation
    • Douglas B.G., and Fowler J.F. The effect of multiple small doses of X rays on skin reactions in the mouse and a basic interpretation. Radiat Res 66 (1976) 401-426
    • (1976) Radiat Res , vol.66 , pp. 401-426
    • Douglas, B.G.1    Fowler, J.F.2
  • 37
    • 0021686098 scopus 로고
    • Tests for the fit of the linear-quadratic model to radiation isoeffect data
    • Tucker S.L. Tests for the fit of the linear-quadratic model to radiation isoeffect data. Int J Radiat Oncol Biol Phys 10 (1984) 1933-1939
    • (1984) Int J Radiat Oncol Biol Phys , vol.10 , pp. 1933-1939
    • Tucker, S.L.1
  • 38
    • 0020045558 scopus 로고
    • Response of rat spinal cord to single and fractionated doses of accelerated heavy ions
    • Leith J.T., McDonald M., Powers-Risius P., et al. Response of rat spinal cord to single and fractionated doses of accelerated heavy ions. Radiat Res 89 (1982) 176-193
    • (1982) Radiat Res , vol.89 , pp. 176-193
    • Leith, J.T.1    McDonald, M.2    Powers-Risius, P.3
  • 39
    • 0032700567 scopus 로고    scopus 로고
    • RBE for carbon track-segment irradiation in cell lines of differing repair capacity
    • Weyrather W.K., Ritter S., Scholz M., et al. RBE for carbon track-segment irradiation in cell lines of differing repair capacity. Int J Radiat Biol 75 (1999) 1357-1364
    • (1999) Int J Radiat Biol , vol.75 , pp. 1357-1364
    • Weyrather, W.K.1    Ritter, S.2    Scholz, M.3
  • 40
    • 0031704937 scopus 로고    scopus 로고
    • Histopathological and morphometric study of the late effects of heavy-ion irradiation on the spinal cord of the rat
    • Okada S., Okeda R., Matsushita S., et al. Histopathological and morphometric study of the late effects of heavy-ion irradiation on the spinal cord of the rat. Radiat Res 150 (1998) 304-315
    • (1998) Radiat Res , vol.150 , pp. 304-315
    • Okada, S.1    Okeda, R.2    Matsushita, S.3
  • 41
    • 0036843179 scopus 로고    scopus 로고
    • Dose-response curves for late functional changes in the normal rat brain after single carbon-ion doses evaluated by magnetic resonance imaging: Influence of follow-up time and calculation of relative biological effectiveness
    • Karger C.P., Debus J., Peschke P., et al. Dose-response curves for late functional changes in the normal rat brain after single carbon-ion doses evaluated by magnetic resonance imaging: Influence of follow-up time and calculation of relative biological effectiveness. Radiat Res 158 (2002) 545-555
    • (2002) Radiat Res , vol.158 , pp. 545-555
    • Karger, C.P.1    Debus, J.2    Peschke, P.3
  • 42
    • 0036271378 scopus 로고    scopus 로고
    • Dose response curves and tolerance doses for late functional changes in the normal rat brain after stereotactic radiosurgery evaluated by magnetic resonance imaging: Influence of end points and follow-up time
    • Karger C.P., Münter M.W., Heiland S., et al. Dose response curves and tolerance doses for late functional changes in the normal rat brain after stereotactic radiosurgery evaluated by magnetic resonance imaging: Influence of end points and follow-up time. Radiat Res 157 (2002) 617-625
    • (2002) Radiat Res , vol.157 , pp. 617-625
    • Karger, C.P.1    Münter, M.W.2    Heiland, S.3
  • 43
    • 0029905859 scopus 로고    scopus 로고
    • Long-term follow-up after radical photon irradiation
    • Catton C., O'Sullivan B., Bell R., et al. Long-term follow-up after radical photon irradiation. Radiother Oncol 41 (1996) 67-70
    • (1996) Radiother Oncol , vol.41 , pp. 67-70
    • Catton, C.1    O'Sullivan, B.2    Bell, R.3
  • 44
    • 0027363930 scopus 로고
    • Chordoma: Results of radiation therapy in eighteen patients
    • Romero J., Cardens H., La Torre A., et al. Chordoma: Results of radiation therapy in eighteen patients. Radiother Oncol 29 (1993) 27-32
    • (1993) Radiother Oncol , vol.29 , pp. 27-32
    • Romero, J.1    Cardens, H.2    La Torre, A.3
  • 45
    • 0034212276 scopus 로고    scopus 로고
    • Stereotactic fractionated radiotherapy for cordomas and chondrosarcomas of the skull base
    • Debus J., Schulz-Ertner D., Schad L., et al. Stereotactic fractionated radiotherapy for cordomas and chondrosarcomas of the skull base. Int J Radiat Oncol Biol Phys 47 (2000) 591-596
    • (2000) Int J Radiat Oncol Biol Phys , vol.47 , pp. 591-596
    • Debus, J.1    Schulz-Ertner, D.2    Schad, L.3
  • 46
    • 0032716554 scopus 로고    scopus 로고
    • Proton therapy for tumors of the skull base
    • Munzenrider J.E., and Liebsch N.J. Proton therapy for tumors of the skull base. Strahlenther Onkol 175 Suppl. II (1999) 57-63
    • (1999) Strahlenther Onkol , vol.175 , Issue.SUPPL. II , pp. 57-63
    • Munzenrider, J.E.1    Liebsch, N.J.2
  • 47
    • 0344837766 scopus 로고    scopus 로고
    • Radiation therapy for chordoma and chondrosarcoma of the skull base and the cervical spine
    • Noël G., Habrand J.-L., Jauffret E., et al. Radiation therapy for chordoma and chondrosarcoma of the skull base and the cervical spine. Strahlenther Onkol 179 (2003) 241-248
    • (2003) Strahlenther Onkol , vol.179 , pp. 241-248
    • Noël, G.1    Habrand, J.-L.2    Jauffret, E.3
  • 48
    • 22144463512 scopus 로고    scopus 로고
    • Chordomas of the base of the skull and upper cervical spine. 100 patients irradiated by a 3D conformal technique combining photon and proton beams
    • Noël G., Feuvret L., Dhermain F., et al. Chordomas of the base of the skull and upper cervical spine. 100 patients irradiated by a 3D conformal technique combining photon and proton beams. Cancer Radiother 9 (2005) 161-174
    • (2005) Cancer Radiother , vol.9 , pp. 161-174
    • Noël, G.1    Feuvret, L.2    Dhermain, F.3
  • 49
    • 0032815468 scopus 로고    scopus 로고
    • Proton radiation therapy for chordomas and chondrosarcomas of the skull base
    • Hug E.B., Loredo L.N., Slater J.D., et al. Proton radiation therapy for chordomas and chondrosarcomas of the skull base. J Neurosurg 91 (1999) 432-439
    • (1999) J Neurosurg , vol.91 , pp. 432-439
    • Hug, E.B.1    Loredo, L.N.2    Slater, J.D.3
  • 50
    • 7444229300 scopus 로고    scopus 로고
    • Clinical results of proton beam therapy for skull base chordoma
    • Igaki H., Tokuuye K., Okumura T., et al. Clinical results of proton beam therapy for skull base chordoma. Int J Radiat Oncol Biol Phys 60 (2004) 1120-1126
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , pp. 1120-1126
    • Igaki, H.1    Tokuuye, K.2    Okumura, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.