A study on antimalarial artemisinin derivatives using MEP maps and multivariate QSAR

Journal of Molecular Modeling

Volumn 14, Issue 1, 2008, Pages 39-48

  Cardoso, Fábio José B ^a   de Figueiredo, Antonio Florêncio ^a   da Silva Lobato, Maycon ^a   de Miranda, Ricardo Moraes ^a   de Almeida, Ruth Catarine O ^a   Pinheiro, José Ciríaco ^a  

^a FEDERAL UNIVERSITY OF PARÁ   (Brazil)

Author keywords

Artemisinin derivatives; MEP maps; Molecularel ectrostatic potential; Partialleast squares modeling; Plasmodium falciparum

Indexed keywords

ARTEMISIN DERIVATIVE;

ANTIMALARIAL ACTIVITY; ARTICLE; ATOM; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRIC POTENTIAL; HYDROPHILICITY; MOLECULAR MODEL; MOLECULAR WEIGHT; MOLECULE; NONHUMAN; PARTIAL LEAST SQUARES REGRESSION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; VALIDATION PROCESS;

ANIMALS; ANTIMALARIALS; ARTEMISININS; CLUSTER ANALYSIS; ELECTROSTATICS; LEAST-SQUARES ANALYSIS; MODELS, CHEMICAL; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; PRINCIPAL COMPONENT ANALYSIS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

PLASMODIUM FALCIPARUM;

EID: 37049016663     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-007-0249-9     Document Type: Article

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