Reply to comments on "highly antimalaria-active artemisinin derivatives: Biological activity does not correlate with chemical reactivity"

Angewandte Chemie - International Edition

Volumn 44, Issue 14, 2005, Pages 2064-2065

  Haynes, Richard K ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Alkylation; Antiviral agents; Heme proteins; Iron porphyrinoids

Indexed keywords

CORRELATION METHODS; SUBSTITUTION REACTIONS;

ANTIMALARIAL ACTIVITY; ANTIMALARIAL AGENTS; ARTEMISININ;

DERIVATIVES;

EID: 17044427198     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200462723     Document Type: Review

References (12)

1. a) R. K. Haynes, W. Y. Ho, H.-W. Chan, B. Fugmann, J. Stetter, S. L. Croft, L. Vivas, W. Peters, B. L. Robinson, Angew. Chem. 2004, 116, 1405-1409; Angew. Chem. Int. Ed. 2004, 43, 1381-1385;
2. a) R. K. Haynes, W. Y. Ho, H.-W. Chan, B. Fugmann, J. Stetter, S. L. Croft, L. Vivas, W. Peters, B. L. Robinson, Angew. Chem. 2004, 116, 1405-1409; Angew. Chem. Int. Ed. 2004, 43, 1381-1385;
3. b) See reference [46] cited in our original communication (Ref. [1a]).
4. S. A.-L. Laurent, A. Robert, B. Meunier, Angew. Chem. 2005, 117, 2096-2099; Angew. Chem. Int. Ed. 2005, 44, 2060-2063.
5. S. A.-L. Laurent, A. Robert, B. Meunier, Angew. Chem. 2005, 117, 2096-2099; Angew. Chem. Int. Ed. 2005, 44, 2060-2063.
6. A. Robert, Y. Coppel, B. Meunier, Chem. Commun. 2002, 414-415.
7. G. A. Biagini, P. G. Bray, D. G. Spiller, M. R. H. White, S. A. Ward, J. Biol. Chem. 2003, 278, 27910-27915.
8. J. Gazelles, A. Robert, B. Meunier, J. Org. Chem. 2002, 67, 609-619.
9. P. M. O'Neill, G. H. Posner, J. Med. Chem. 2004, 47, 2945-2964.
10. S. Krishna, S., A.- C. Uhlemann, R. K. Haynes, Drug Resist. Updates 2004, 7, 233-244, and references therein.
11. R. K. Haynes, Curr. Opin. Infect. Dis. 2001, 14, 719-726.
12. U. Eckstein-Ludwig, R. J. Webb, I. D. A. van Goethem, J. M. East, A. G. Lee, M. Kimura, P. M. O'Neill, P. G. Bray, S. A. Ward, S. Krishna, Nature 2003, 424, 957-961.