-
1
-
-
0022343014
-
Molybdenum hydroxylases as drug-metabolizing enzymes
-
Beedham, C. (1985) Molybdenum hydroxylases as drug-metabolizing enzymes. Drug Metab. Rev. 16, 119-156.
-
(1985)
Drug Metab. Rev
, vol.16
, pp. 119-156
-
-
Beedham, C.1
-
2
-
-
0023528062
-
Molybdenum hydroxylases: Biological distribution and substrate-inhibitor specificity
-
Beedham, C. (1987) Molybdenum hydroxylases: Biological distribution and substrate-inhibitor specificity. Prog. Med. Chem. 24, 85-121.
-
(1987)
Prog. Med. Chem
, vol.24
, pp. 85-121
-
-
Beedham, C.1
-
3
-
-
0030772328
-
The role of non-P450 enzymes in drug oxidation
-
Beedham, C. (1997) The role of non-P450 enzymes in drug oxidation. Pharm. World Sci. 19, 255-263.
-
(1997)
Pharm. World Sci
, vol.19
, pp. 255-263
-
-
Beedham, C.1
-
4
-
-
34247367464
-
Molybdenum hydroxylases
-
Gorrod, J. W, Oeschlager, H, and Caldwell, J, eds, pp, Taylor and Francis, London and New York, USA
-
Beedham, C. (1998) Molybdenum hydroxylases; in Metabolism of Xenobiotics, Gorrod, J. W., Oeschlager, H., and Caldwell, J. (eds), pp. 51-58, Taylor and Francis, London and New York, USA.
-
(1998)
Metabolism of Xenobiotics
, pp. 51-58
-
-
Beedham, C.1
-
5
-
-
0038077862
-
Molybdenum hydroxylase
-
Ioannides, C, ed, pp, John Wiley, Chichester, UK
-
Beedham, C. (2002) Molybdenum hydroxylase; in Enzyme Systems that Metabolise Drug and Other Xenobiotics, Ioannides, C. (ed.), pp. 147-187, John Wiley, Chichester, UK.
-
(2002)
Enzyme Systems that Metabolise Drug and Other Xenobiotics
, pp. 147-187
-
-
Beedham, C.1
-
6
-
-
0038722339
-
Ziprasidone metabolism, aldehyde oxidase, and clinical implications
-
Beedham, C., Miceli, J. J. and Obach, S. (2003) Ziprasidone metabolism, aldehyde oxidase, and clinical implications. J. Clin. Psychopharm. 23, 229-232.
-
(2003)
J. Clin. Psychopharm
, vol.23
, pp. 229-232
-
-
Beedham, C.1
Miceli, J.J.2
Obach, S.3
-
7
-
-
0014216473
-
Genetic variations of an oxidase in mammals
-
Glueksohn-Waelsch, S., Greengard, P., Quinn, G. P. and Teicher, L. S. (1967) Genetic variations of an oxidase in mammals. J. Biol. Chem. 242, 1271-1273.
-
(1967)
J. Biol. Chem
, vol.242
, pp. 1271-1273
-
-
Glueksohn-Waelsch, S.1
Greengard, P.2
Quinn, G.P.3
Teicher, L.S.4
-
8
-
-
0033560621
-
Molecular cloning of retinal oxidase/aldehyde oxidase cDNA from rabbit and mouse liver and functional expression of recombinant mouse retinal oxidase cDNA in Escherichia coli
-
Huang, D. Y., Furukawa, A. and Ichikawa, Y. (1999) Molecular cloning of retinal oxidase/aldehyde oxidase cDNA from rabbit and mouse liver and functional expression of recombinant mouse retinal oxidase cDNA in Escherichia coli. Arch Biochem. Biophys. 364, 264-272.
-
(1999)
Arch Biochem. Biophys
, vol.364
, pp. 264-272
-
-
Huang, D.Y.1
Furukawa, A.2
Ichikawa, Y.3
-
9
-
-
24144483424
-
Stereospecific oxidation of (S)-enantiomer of RS-8359, a selective and reversible MAO-A inhibitor, by aldehyde oxidase
-
Itoh, K., Yamamura, M., Muramatsu, S., Hoshino, K., Masubuchi, A., Sasaki, T. and Tanaka, Y. (2005) Stereospecific oxidation of (S)-enantiomer of RS-8359, a selective and reversible MAO-A inhibitor, by aldehyde oxidase. Xenobiotica 35, 561-573.
-
(2005)
Xenobiotica
, vol.35
, pp. 561-573
-
-
Itoh, K.1
Yamamura, M.2
Muramatsu, S.3
Hoshino, K.4
Masubuchi, A.5
Sasaki, T.6
Tanaka, Y.7
-
10
-
-
33646356964
-
Species differences in enantioselective 2-oxidation of RS-8359, a selective and reversible MAO-A inhibitor, and cinchona alkaloids by aldehyde oxidase
-
Itoh, K., Yamamura, M., Takasaki, W., Sasaki, T., Masubuchi, A. and Tanaka, Y. (2006) Species differences in enantioselective 2-oxidation of RS-8359, a selective and reversible MAO-A inhibitor, and cinchona alkaloids by aldehyde oxidase. Biopharm. Drug Dispos. 27, 1133-1139.
-
(2006)
Biopharm. Drug Dispos
, vol.27
, pp. 1133-1139
-
-
Itoh, K.1
Yamamura, M.2
Takasaki, W.3
Sasaki, T.4
Masubuchi, A.5
Tanaka, Y.6
-
11
-
-
34247382521
-
Polymorphism of aldehyde oxidase in Donryu rats
-
Itoh, K., Masubuchi, A., Sasaki, T., Adachi, M., Watanabe, N., Nagata, K., Yamazoe, Y., Hiratsuka, M., Mizugaki, M. and Tanaka, Y. (2007) Polymorphism of aldehyde oxidase in Donryu rats. Drug Metab. Dispos. 35, 734-739.
-
(2007)
Drug Metab. Dispos
, vol.35
, pp. 734-739
-
-
Itoh, K.1
Masubuchi, A.2
Sasaki, T.3
Adachi, M.4
Watanabe, N.5
Nagata, K.6
Yamazoe, Y.7
Hiratsuka, M.8
Mizugaki, M.9
Tanaka, Y.10
-
12
-
-
14844335195
-
A novel selective and reversible MAO-A inhibitor, RS-8359: Its pharmacological properties and metabolism
-
Iwata, N., Tonohiro, T., Kozuka, M., Kumagae, Y., Takasaki, W. and Tanaka, Y. (1996) A novel selective and reversible MAO-A inhibitor, RS-8359: its pharmacological properties and metabolism. Int. Acad. Biomed. Drug Res. 11, 285-286.
-
(1996)
Int. Acad. Biomed. Drug Res
, vol.11
, pp. 285-286
-
-
Iwata, N.1
Tonohiro, T.2
Kozuka, M.3
Kumagae, Y.4
Takasaki, W.5
Tanaka, Y.6
-
13
-
-
0032992164
-
Aldehyde oxidase-catalyzed oxidation of methotrexate in the liver of guinea pig, rabbit and man
-
Jordan, C. G. M., Rashidi, M. R., Laljee, H., Clarke, S. E., Brown, J. E. and Beedham, C. (1999) Aldehyde oxidase-catalyzed oxidation of methotrexate in the liver of guinea pig, rabbit and man. J. Pharm. Pharmacol. 51, 411-418.
-
(1999)
J. Pharm. Pharmacol
, vol.51
, pp. 411-418
-
-
Jordan, C.G.M.1
Rashidi, M.R.2
Laljee, H.3
Clarke, S.E.4
Brown, J.E.5
Beedham, C.6
-
14
-
-
0033378603
-
Variation of hepatic methotrexate 7-hydroxylase activity in animals and humans
-
Kitamura, S., Sugihara, K., Nakatani, K., Ohta, S., O'Hara, T., Nimomiya, S., Green, C. E. and Tyson, C. A. (1999a) Variation of hepatic methotrexate 7-hydroxylase activity in animals and humans. IUBMB Life. 48, 607-611.
-
(1999)
IUBMB Life
, vol.48
, pp. 607-611
-
-
Kitamura, S.1
Sugihara, K.2
Nakatani, K.3
Ohta, S.4
O'Hara, T.5
Nimomiya, S.6
Green, C.E.7
Tyson, C.A.8
-
15
-
-
0033018175
-
Strain differences of the ability to hydroxylate methotrexate in rats
-
Kitamura, S., Nakatani, K., Sugihara, K., and Ohta, S. (1999b) Strain differences of the ability to hydroxylate methotrexate in rats. Com. Biochem. Phys. Part C 122, 331-336.
-
(1999)
Com. Biochem. Phys. Part C
, vol.122
, pp. 331-336
-
-
Kitamura, S.1
Nakatani, K.2
Sugihara, K.3
Ohta, S.4
-
16
-
-
33744979094
-
Drug-metabolizing ability of molybdenum hydroxylases
-
Kitamura, S., Sugihara, K. and Ohta, S. (2006) Drug-metabolizing ability of molybdenum hydroxylases. Drug Metab. Pharmacokinet. 21, 83-98.
-
(2006)
Drug Metab. Pharmacokinet
, vol.21
, pp. 83-98
-
-
Kitamura, S.1
Sugihara, K.2
Ohta, S.3
-
17
-
-
0025978617
-
Deamination of norepinephrine, dopamine, and serotonin by type A monoamine oxidase in discrete regions of the rat brain and inhibition by RS-8359
-
Kumagae, Y., Matsui, Y. and Iwata, N. (1991) Deamination of norepinephrine, dopamine, and serotonin by type A monoamine oxidase in discrete regions of the rat brain and inhibition by RS-8359. Jpn. J. Pharmacol. 55, 121-128.
-
(1991)
Jpn. J. Pharmacol
, vol.55
, pp. 121-128
-
-
Kumagae, Y.1
Matsui, Y.2
Iwata, N.3
-
18
-
-
0027787990
-
Changes in monoamine levels in mouse brain elicited by forced-swimming stress, and the protective effect of a new monoamine oxidase inhibitor, RS-8359
-
Miura, H., Naoi, M., Nakahara, D., Ohta, T. and Nagatsu, T. (1993) Changes in monoamine levels in mouse brain elicited by forced-swimming stress, and the protective effect of a new monoamine oxidase inhibitor, RS-8359. J. Neural Transm. 94, 175-187.
-
(1993)
J. Neural Transm
, vol.94
, pp. 175-187
-
-
Miura, H.1
Naoi, M.2
Nakahara, D.3
Ohta, T.4
Nagatsu, T.5
-
19
-
-
0031464456
-
The effects of RS-8359 on cardiovascular function in healthy subjects and depressed patients
-
Plenker, A., Puchler, K. and Volz, H. P. (1997) The effects of RS-8359 on cardiovascular function in healthy subjects and depressed patients. Int. Clin. Psychopharm. 12, S25-S29.
-
(1997)
Int. Clin. Psychopharm
, vol.12
-
-
Plenker, A.1
Puchler, K.2
Volz, H.P.3
-
20
-
-
0030752510
-
Metabolism and excretion of a new antipsychotic drug, ziprasidone, in humans
-
Prakash, C., Kamel, A., Gummerus, J. and Wilner, K. (1997) Metabolism and excretion of a new antipsychotic drug, ziprasidone, in humans. Drug Metab. Dispos. 25, 863-875.
-
(1997)
Drug Metab. Dispos
, vol.25
, pp. 863-875
-
-
Prakash, C.1
Kamel, A.2
Gummerus, J.3
Wilner, K.4
-
21
-
-
0031437471
-
The comparative effects of single and multiple doses of RS-8359, moclobemide and placebo on psychomotor function in healthy subjects
-
Puchler, K., Schaffler, K. and Plenker, A. (1997) The comparative effects of single and multiple doses of RS-8359, moclobemide and placebo on psychomotor function in healthy subjects. Int. Clin. Psychopharm. 12, 17-23.
-
(1997)
Int. Clin. Psychopharm
, vol.12
, pp. 17-23
-
-
Puchler, K.1
Schaffler, K.2
Plenker, A.3
-
22
-
-
0030840879
-
In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit and rat liver
-
Rashidi, M. R., Smith, J. A., Clarke, S. E. and Beedham, C. (1997) In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit and rat liver. Drug Metab. Dispos. 25, 805-813.
-
(1997)
Drug Metab. Dispos
, vol.25
, pp. 805-813
-
-
Rashidi, M.R.1
Smith, J.A.2
Clarke, S.E.3
Beedham, C.4
-
23
-
-
33746456808
-
Rat strain differences in stereospecific 2-oxidation of RS-8359, a reversible and selective MAO-A inhibitor, by aldehyde oxidase
-
Sasaki, T., Masubuchi, A., Yamamura, M., Watanabe, N., Hiratsuka, M., Mizugaki, M., Itoh, K. and Tanaka, Y. (2006) Rat strain differences in stereospecific 2-oxidation of RS-8359, a reversible and selective MAO-A inhibitor, by aldehyde oxidase. Biopharm. Drug Dispos. 27, 247-255.
-
(2006)
Biopharm. Drug Dispos
, vol.27
, pp. 247-255
-
-
Sasaki, T.1
Masubuchi, A.2
Yamamura, M.3
Watanabe, N.4
Hiratsuka, M.5
Mizugaki, M.6
Itoh, K.7
Tanaka, Y.8
-
24
-
-
0029553627
-
Strain differences of liver aldehyde oxidase in rats
-
Sugihara, K., Kitamura, S. and Tatsumi, K. (1995) Strain differences of liver aldehyde oxidase in rats. Biochem. Mol. Biol. Int. 37, 861-869.
-
(1995)
Biochem. Mol. Biol. Int
, vol.37
, pp. 861-869
-
-
Sugihara, K.1
Kitamura, S.2
Tatsumi, K.3
-
25
-
-
14844300091
-
Stereoselective pharmacokinetics of RS-8359, a selective and reversible MAO-A inhibitor, by species-dependent drug metabolizing enzymes
-
Takasaki, W., Yamamura, M., Nozaki, A., Nitanai, T., Sasahara, K., Itoh, K. and Tanaka, Y. (2005) Stereoselective pharmacokinetics of RS-8359, a selective and reversible MAO-A inhibitor, by species-dependent drug metabolizing enzymes. Chirality 17, 135-141.
-
(2005)
Chirality
, vol.17
, pp. 135-141
-
-
Takasaki, W.1
Yamamura, M.2
Nozaki, A.3
Nitanai, T.4
Sasahara, K.5
Itoh, K.6
Tanaka, Y.7
-
26
-
-
0033525193
-
cDNA cloning, sequencing, and characterization of male and female rat liver aldehyde oxidase (rAOX1)
-
Wright, R. M., Clayton, D. A., Riley, M. G., McManaman, J. L. and Repine, J. E. (1999) cDNA cloning, sequencing, and characterization of male and female rat liver aldehyde oxidase (rAOX1). J. Biol. Chem. 274, 3878-3886.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 3878-3886
-
-
Wright, R.M.1
Clayton, D.A.2
Riley, M.G.3
McManaman, J.L.4
Repine, J.E.5
-
27
-
-
36949002370
-
Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: Role of active site residues in binding and activation of purine substrate
-
Yamaguchi, Y., Matsumura, T., Ichida, K., Okamoto, K. and Nishino, T. (2007) Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: role of active site residues in binding and activation of purine substrate. J. Biochem. 141, 513-524.
-
(2007)
J. Biochem
, vol.141
, pp. 513-524
-
-
Yamaguchi, Y.1
Matsumura, T.2
Ichida, K.3
Okamoto, K.4
Nishino, T.5
-
28
-
-
0024498392
-
Comparative studies of the effects of RS-8359 and safrazine on monoamine oxidase in vitro and in vivo in mouse brain
-
Yokoyama, T., Karube, T. and Iwata, N. (1989) Comparative studies of the effects of RS-8359 and safrazine on monoamine oxidase in vitro and in vivo in mouse brain. J. Pharm. Pharmacol. 41, 32-36.
-
(1989)
J. Pharm. Pharmacol
, vol.41
, pp. 32-36
-
-
Yokoyama, T.1
Karube, T.2
Iwata, N.3
|