Activation of 5-lipoxygenase and NF-κB in the action of acenaphthenequinone by modulation of oxidative stress

Toxicological Sciences

Volumn 101, Issue 1, 2008, Pages 152-158

  Chung, Sang Woon ^a,b   Toriba, Akira ^a   Chung, Hae Young ^b   Yu, Byung Pal ^c   Kameda, Takayuki ^a   Tang, Ning ^a   Kizu, Ryoichi ^d   Hayakawa, Kazuichi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b Pusan National University   (South Korea)

^c Mays Cancer Center at UT Health San Antonio   (United States)

^d DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

Author keywords

5 lipoxygenase; Acenaphthenequinone; Inflammation; NF B; Quinoid PAHs; Reactive species

Indexed keywords

ACETYLCYSTEINE; ARACHIDONATE 5 LIPOXYGENASE; DOCEBENONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUKOTRIENE B4; LIPOXYGENASE INHIBITOR; POLYCYCLIC AROMATIC HYDROCARBON; QUINONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SEMIQUINONE; XANTHINE OXIDASE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; RESPIRATORY BURST;

ACENAPHTHENES; ACETYLCYSTEINE; ANTIOXIDANTS; ARACHIDONATE 15-LIPOXYGENASE; BENZOQUINONES; BIOTRANSFORMATION; BLOTTING, WESTERN; CELL LINE, TUMOR; ENZYME ACTIVATION; GENES, REPORTER; HUMANS; IMMUNOENZYME TECHNIQUES; INDICATORS AND REAGENTS; INFLAMMATION; LEUKOTRIENE B4; LUCIFERASES; NF-KAPPA B; OXIDATIVE STRESS; UP-REGULATION;

EID: 36949012548     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm252     Document Type: Article

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