Comparative study of the prereactive protein kinase A Michaelis complex with Kemptide substrate

Journal of Computer-Aided Molecular Design

Volumn 21, Issue 10-11, 2007, Pages 603-615

  Montenegro, Manuel ^a   Garcia Viloca, Mireia ^a   González Lafont, Àngels ^a   Lluch, José M ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Classical molecular dynamics; Kemptide; Molecular modeling; Protein kinase A; Reaction mechanism; Substrate binding

Indexed keywords

ENZYMES; REACTION KINETICS;

ADENOSINE MONOPHOSPHATE; CLASSICAL MOLECULAR DYNAMICS; COMPARATIVES STUDIES; CYCLIC ADENOSINE; HEPTAPEPTIDES; KEMPTIDE; MICHAELIS COMPLEX; PROTEIN KINASE A; REACTION MECHANISM; SUBSTRATE-BINDING;

MOLECULAR DYNAMICS;

CYCLIC AMP DEPENDENT PROTEIN KINASE; KEMPTIDE;

ARTICLE; COMPARATIVE STUDY; COMPLEX FORMATION; COMPUTER SIMULATION; CONTROLLED STUDY; ENZYME SUBSTRATE; MICHAELIS CONSTANT; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; MOLECULAR MIMICRY; MOLECULAR MODEL; OSCILLATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

EID: 36949003228     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-007-9143-x     Document Type: Article

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