Affinity of dinucleotide cap analogues for human decapping scavenger (hDcpS)

Nucleosides, Nucleotides and Nucleic Acids

Volumn 26, Issue 10-12, 2007, Pages 1349-1352

  Darzynkiewicz, Zbigniew M ^a   Bojarska, Elzbieta ^a   Stepinski, Janusz ^a   Jemielity, Jacek ^a   Jankowska Anyszka, Marzena ^a   Davis, Richard E ^b   Darzynkiewicz, Edward ^a  

^a UNIVERSITY OF WARSAW   (Poland)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

hDcpS; mRNA cap analogues; Scavenger decapping enzymes

Indexed keywords

CAPPED RNA; DINUCLEOTIDE; ENZYME; HUMAN DECAPPING SCAVENGER; HYDROLASE; OLIGORIBONUCLEOTIDE; PURINE; PYRIMIDINE; SCAVENGER; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; EUKARYOTIC CELL; HYDROLYSIS; RNA DEGRADATION;

DINUCLEOSIDE PHOSPHATES; ENDORIBONUCLEASES; HUMANS; HYDROLYSIS; RNA CAP ANALOGS; RNA STABILITY;

EUKARYOTA;

EID: 36949000665     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770701533818     Document Type: Article

References (13)

1. Ross, J. Eukaryotic mRNA degradation. Microbiol Rev. 1995, 59, 423-450.
2. Parker, R.; Song, H. The enzymes and control of eukaryotic mRNA turnover. Struc. Mol. Biol. 2004, 11, 121-127.
3. Van Dijk, E.; Le Hir, H.; Seraphin, B. DcpS can act in the 3′-5′ mRNA decay pathway in addition to the 5′-3′ pathway. Proc. Natl. Acad. Sci. USA 2003, 100, 12081-12086.
4. Liu, H.; Rodgers, N.D.; Jiao, X.; Kiledijan, M. The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases. EMBO J. 2002, 21, 4699-4708.
5. Lima, C.D.; Klein, M.G.; Hendrickson, W.A. Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science 1997, 278, 286-290.
6. Gu, M.; Fabrega, C.; Liu, S.W.; Liu, H.; Kiledjian, M.; Lima, C.D. Insight into the structure mechanism and regulation of scavenger mRNA decapping activity. Mol. Cell 2004, 14, 67-80.
7. 1, P-dinucleoside di-, tri- and tetraphosphate mRNA 5′-cap analogues. Nucleosides Nucleotides 1995, 14, 717-121.
8. 1H NMR and fluorescence studies of new mRNA 5′ cap analogues. Collect. Czech. Chem. Commun. 1996, 61, S197-S202.
9. Jemielity, J.; Fowler, T.; Zuberek, J.; Stepinski, J.; Lewdorowicz, M.; Niedzwiecka, A.; Stolarski, R.; Darzynkiewicz, E.; Rhoads, R.E. Novel 'anti-reverse' cap analogs with superior translational properties. RNA 2003, 9, 1108-1122.
10. Stepinski, J.; Zuberek, J.; Jemielity, J.; Kalek, M.; Stolarski, R.; Darzynkiewicz, E. Novel dinucleoside 5′,5′-triphosphate cap analogues. Synthesis and affinity for murine translation factor eIF4E. Nucleosides, Nucleotides Nucleic Acids 2005, 24, 629-633.
11. Kalek, M.; Jemielity, J.; Darzynkiewicz, Z.M.; Bojarska, E.; Stepinski, J.; Stolarski, R.; Davis, R.E.; Rhoads, R.E.; Darzynkiewicz, E. Enzymatically stable 5′ mRNA cap analogues: Synthesis and binding studies with human decapping enzyme. Bioorg. Med. Chem. 2006, 14, 3223-3230.
12. 3-triphosphate hydrolase. Biochemistry 1996, 35, 11529-11535.
13. Kwasnicka, D.A.; Krakowiak, A.; Thacker, C.; Brenner, C.; Vincent, S.R. Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and hint-related 7meGMP-directed hydrolase, DCS-1. J. Biol. Chem. 2003, 278, 39051-3905.