Antiproliferation of hepatoma cell and progression of cell cycle as affected by isoflavone extracts from soybean cake

International Journal of Molecular Sciences

Volumn 8, Issue 11, 2007, Pages 1095-1110

  Kao, Tsai Hua ^a   Huang, Rwei Fen S ^a   Chen, Bing Huei ^a  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

Cell cycle analysis; Isoflavone extracts; MTT test; Soybean cake

Indexed keywords

ACETYLDAIDZIN; ACETYLGENISTIN; ACETYLGLUCOSIDE; ACETYLGLYCITIN; AGLYCONE; DAIDZEIN; DAIDZIN; GENISTEIN; GENISTIN; GLUCOSIDE; GLYCITEIN; GLYCITIN; ISOFLAVONE; MALONYLDAIDZIN; MALONYLGENISTIN; MALONYLGLUCOSIDE; MALONYLGLYCITIN; PHENOL DERIVATIVE; SAPONIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE; CELL GROWTH; CELL PROLIFERATION; COLUMN CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HEPATOMA CELL; HUMAN; HUMAN CELL; SOYBEAN;

GLYCINE MAX;

EID: 36849083537     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/i8111092     Document Type: Article

References (43)

1. World Cancer Research Fund, American Institute for Cancer Research. Food, nutrition and the prevention of cancer: a global perspective; American Institute for Cancer Research: Washington, 1997.
2. Adlercreutz, H. Phyto-oestrogens and cancer. Lancet Oncol. 2002, 3, 364-372.
3. Block, G.; Patterson, B.; Subar, A. Fruits, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr. Cancer. 1992, 18, 1-29.
4. Messina, M.; Deshcheemaker, K.; Erdman, J.W. The role of soy in preventing and treating chronic disease. Am. J. Clin. Nutr. 1998, 68, 1329-1544.
5. Adlercreutz, H.; Honjo, H.; Higash, A. Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming traditional Japanese diet. Am. J. Clin. Nutr. 1991, 54, 1093-1100.
6. Dixon, R.A.; Ferreira, D. Genistein. Phytochemistry 2002, 60, 205-211.
7. Peterson, G.; Barnes, S. Genistein inhibition of the growth of human breast cancer cells: Independence from estrogen receptors and the multi-drug resistance gene. Biochem. Biophys. Res. Commun. 1991, 179, 661-667.
8. Scholar, E.M.; Toews, M.L. Inhibition of invasion of murine mammary carcinoma cells by the tyrosine kinase inhibitor genistein. Cancer Lett. 1994, 87, 159-162.
9. kip1, and Cdc25C expression. Biochem. Pharmacol. 2001, 61, 979-989.
10. Kumi-Diaka, J. Chemosensitivity of human prostate cancer cells PC3 and LNCaP to genistein isoflavone and β-lapachone. Bio. Cell. 2002, 94, 37-44.
11. Chang, K.L.; Kung, M.L.; Chow, N.H.; Su, S.J. Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulationof p21waf1/cip1 and Weel. Biochem. Pharmacol. 2004, 67, 717-726.
12. Di Virgilio, A.L.; Iwami, K.; Wätjjen, W.; Kahl, R.; Gegen, G.H. Genotoxicity of the isoflavones genistein, daidzein and equol in V79 cells. Toxicol. Lett. 2004, 151, 151-162.
13. Oki, T.; Sowa, Y.; Hirose, T.; Takagaki, N.; Horinaka, M.; Nakanishi, R.; Yasuda, C.; Yoshida, T.; Kanazawa, M.; Satomi, Y.; Nishino, H.; Miki, T.; Sakai, T. Genistein induces Gadd45 gene and G2/M cell cycle arrest in the DU145 human prostate cancer cell line. FEBS Lett. 2004, 577, 55-59.
14. Kao, T.H.; Chen, B.H. Functional components in soybean cake and their effects on antioxidant activity. J. Agric. Food Chem. 2006, 54, 7544-7555.
15. Hewitt, A.L.; Singletary, K.W. Soy extract inhibits mammary adenocarcinoma growth in a syngeneic mouse model. Cancer Lett. 2003, 192, 133-143.
16. Constantinou, A.I.; Mehta, R.G.; Vaughan, A. Inhibition of N-methyl-N-nitrosourea-induced mammary tumors in rats by the soybean isoflavones. Anticancer Res. 1996, 16, 3293-3298.
17. Sakamoto, K. Synergistic effects of thearubigin and genistein on human prostate tumor cell (PC-3) growth via cell cycle arrest. Cancer Lett. 2000, 151, 103-109.
18. Wei, H.; Wei, L.; Frenkel, K.; Bowen, R.; Barnes, S. Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein. Nutr. Cancer 1993, 20, 1-12.
19. Wei, H.; Bower, R.; Zhang, X.; Lebwohl, M. Isoflavone genistein inhibits the initiation and promotion of two-stage skin carcinogenesis in mice. Carcinogenesis 1998, 19, 1509-1514.
20. van Rossen, M.E.; Sluiter, W.; Bonthuis, F.; Jeekel, H.; Marquet, R.L.; van Eijck, C.H. Scavenging of reactive oxygen species leads to diminished peritoneal tumor recurrence. Cancer Res. 2000, 60, 5625-5629.
21. Bostwick, D.G.; Alexander, E.E.; Singh, R.; Shan A.; Qian J.; Santella, R.M.; Oberley, L.W.; Yan, T.; Zhong, W.; Jiang, X.; Oberley, T.D. Antioxidant enzyme expression and reactive oxygen species damage in prostatic intraepithelial neoplasia and cancer. Cancer 2000, 89, 123-134.
22. 2-mediated oxidative stress activates NF-kappaB in lens epithelial cells. Free Radic. Biol. Med. 2001, 31, 651-658.
23. Popiolkiewicz, J.; Polkowski, K.; Skierski, S.; Mazurek, A.P. In vitro toxicity evaluation in the development of new anticancer drugs-genistein glycosides. Cancer Lett. 2005, 229, 67-75.
24. Papazisis, K.T.; Zambouli, D.; Kimoundri, O.T.; Papadakis, E.S.; Vala, V.; Deromichalos, D.; Voyatzi, S.; Markala, D.; Destouni, E.; Boutis, L.; Kortsaris, A.H. Protein tyrosine kinase inhibitor, genistein, enhances apoptosis and cell cycle arrest in K562 cells treated with γ-irradiation. Cancer Lett. 2000, 160, 107-113.
25. CIP1 is dispensable for the G2 arrest caused by genistein in human melanoma cells. Exp. Cell Res. 2000, 258, 101-108.
26. Ying, C.; Hsu, J.T.; Hung, H.C.; Lin, D.H.; Chen, L.F.O.; Wang, L.K. Growth and cell cycle regulation by isoflavones in human breast carcinoma cells. Reprod. Nutr. Dev. 2002, 42, 55-64.
27. waf1/cip1, Bax and Bcl-2. Korea J. Pathol. 2006, 40, 39-347.
28. Katdare, M.; Osborne, M.; Telang, N.T. Soy isoflavone genistein modulates cell cycle progression and induces apoptosis in HER-2/neu oncogene expressing human breast epithelial cells. Int. J. Oncol. 2002, 21, 809-815.
29. Sarkar, F.H.; Li, Y. Mechanisms of cancer chemoprevention by soy isoflavone genistein. Cancer Metastasis Rev. 2002, 21, 265-280.
30. Li, Y.; Bhuiyan, M.; Alhasan, S.; Senderowicz, A.M.; Sarkar, F.H. Induction of apoptosis and inhibition of c-erbB-2 in breast cancer cells by flavopiridol. Clin. Cancer Res. 2000, 6, 223-229.
31. Su, S.J.; Yeh, T.M.; Chuang, W.J.; Ho, C.L.; Chang, K.L.; Cheng, H.L.; Liu, H.S.; Cheng, H.L.; Hsu, P.Y.; Chow, N.H. The novel targets for anti-angiogenesis of genistein on human cancer cells. Biochem. Pharmacol. 2005, 69, 307-318.
32. Conklin, C.M.J.; Bechberger, J.F.; MacFabe, D.; Guthrie, N.; Kurowska, E.M.; Naus, C.C. Genistein and quercetin increase connexin 43 and suppress growth of breast cancer cells. Carcinogenesis 2007, 28, 93-100.
33. Kim, H.Y.; Yu, R.; Kim, J.S.; Kim, Y.K.; Sung, M.K. Antiproliferative crude soy saponin extract modulates the expression of IκBα, protein kinase C, and cyclooxygenase-2 in human colon cancer cells. Cancer Lett. 2004, 210, 1-6.
34. Ellington, A.A.; Berhow, M.; Singletary, K.W. Induction of macroautophagy in human colon cancer cells by soybean B-group triterpenoid saponins. Carcinogenesis 2005, 26, 159-167.
35. Ellington, A.A.; Berhow, M.; Singletary, K.W. Inhibitionof Akt signaling and enhanced ERK1/2 activity are involved in induction of marcoautophagy by triterpenoid B-group soyasaponins in colon cancer cells. Carcinogenesis 2006, 27, 298-306.
36. Dalais, F.S.D.; Meliala, A.; Wattanapenpaiboon, N.; Frydenberg, M.; Siter, D.A.I.S; Thomson, W.K.; Wahlqvist, M.L. Effects of a diet rich in phytoestrogens on prostate-specific antigen and sex hormones in men diagnosed with prostate cancer. Urology. 2004, 64, 510-515.
37. Stephens, F.O. Phytoestrogens and prostate cancer: possible preventive role. Med. J. Aust. 1997, 167, 138-140.
38. Galati, G.; O'Brien, P.J. Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. Free Radic. Biol. Med. 2004, 37, 287-303.
39. McClain R.M.; Wolz, E.; Davidovich, A.; Bausch, J. Genetic toxicity studies with genistein. Food Chem. Toxicol. 2006, 44, 42-55.
40. McClain R.M.; Wolz, E.; Davidovich, A.; Edwards, J.; Bausch, J. Reproductive safety studies with genistein in rats. Food Chem. Toxicol. 2007, 45, 1319-1332.
41. Kao, T.H.; Lu, Y.F.; Chen, B.H. Preparative chromatography of four groups of isoflavones from soybean cake. Eur. Food Res. Technol. 2005, 221, 459-465.
42. Hsieh, H.C.; Kao, T.H.; Chen, B.H. A fast HPLC method for analysis of isoflavones in soybean. J. Liquid Chrom. Rel. Technol. 2004, 27, 315-324.
43. SAS. SAS Procedures and SAS/Graph User's Guide, version 6, Software Release 8.2 (TS2MO) of the SAS System for Microsoft Windows; SAS Institute, Inc.: Cary, NC, 2004.